NASDAQ$CRSP

CRISPR Therapeutics AG · Q3 2020 earnings

Q3 2020 earnings · · Investor relations

Briefing

Reported a net loss due to increased operating expenses and decreased collaboration revenue.

CRISPR Therapeutics reported positive top-line results from its Phase 1 CARBON trial of CTX110, received FDA designations for CTX001 and CTX120, and began treating patients in CTX130 trials. The company's cash position increased due to a public offering, but collaboration revenue decreased significantly, leading to a net loss for the quarter.

  • Reported positive top-line results from the Phase 1 CARBON trial of CTX110 for B-cell malignancies.
  • Received Rare Pediatric Disease designation from the FDA for CTX001 for sickle cell disease and transfusion-dependent beta thalassemia.
  • Received Orphan Drug Designation (ODD) for CTX120 for relapsed or refractory multiple myeloma.
  • Began treating patients in Phase 1 clinical trials of CTX130 for solid tumors and hematologic malignancies.

Headline financials

Total Revenue

$148K

Previous: $212M-99.9%
EPS (adj)

-$1.32

Previous: $2.40-155.0%
Capital Expenditures

-$12.1M

Previous: -$5.73M-111.4%
Free Cash Flow

-$105M

Previous: $133M-178.8%
Net Income

-$92.4M

Previous: $138M-166.8%
Operating Income

-$92.4M

Previous: $139M-166.4%
Gross Profit

-$70.9M

Previous: $212M-133.4%
Cash & Equivalents

$1.04B

Previous: $630M+65.4%
Total Assets

$1.49B

Previous: $721M+106.1%
Stock-Based Comp

$17.2M

Previous: $11.3M+52.0%

Revenue & EPS history

CRISPR Therapeutics · Revenue · Quarterly

$148K

Q3 2020-99.9%vs Q3 2019
Beat estimate in 12 of 16 quarters(75%)
ActualEstimate

Revenue by segment

CRISPR Therapeutics · $762K total across 1 segment · Q1 2022

  • Grant Revenue
    $762K+126.1%

Forward guidance

CRISPR Therapeutics expects to report additional data from the CTX001 program later this year and initial data for the CTX120 and CTX130 programs next year. They also plan to initiate a Phase 1/2 trial of their allogeneic stem cell-derived therapy for Type 1 diabetes in 2021.

Tailwinds

  • Reporting additional data from CTX001 program later this year.
  • Reporting initial data for CTX120 and CTX130 programs next year.
  • Initiating Phase 1/2 trial of allogeneic stem cell-derived therapy for Type 1 diabetes in 2021.
  • Advancing clinical trials in hemoglobinopathies rapidly.
  • Continuing enrollment in CTX120 and CTX130 trials.

Headwinds

  • Potential delays in regulatory review due to the coronavirus pandemic.
  • Manufacturing and supply chain interruptions.
  • Adverse effects on healthcare systems.
  • Disruption of the global economy.
  • Uncertainties regarding intellectual property protection.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2020

Historical avgQ3 2020

+2.1%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+1.4%

Avg return

30 days after

48%

19 / 40 earnings

Positive

+22.8%

Q3 2019

Best reaction

-7.7%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.1%+2.4%+6.3%
Q4 2025+1.2%+10.0%+0.9%
Q3 2025-1.0%-4.7%+4.5%
Q1 2025-0.1%-3.2%+7.2%
Q4 2024-2.8%-8.3%-18.2%
Q3 2024+0.3%+2.0%-2.1%
Q2 2024-3.5%-8.0%-11.9%
Q1 2024-3.6%+0.2%+4.2%
Q4 2023+9.5%+9.3%-9.0%
Q3 2023+14.9%+4.3%+39.5%
Q2 2023+4.1%-2.6%+0.3%
Q1 2023+13.7%+14.5%+12.5%
Q4 2022-1.0%-5.6%-15.2%
Q3 2022+4.5%-2.2%+3.8%
Q2 2022-7.7%-3.4%-20.1%
Q1 2022-1.5%+8.8%+53.8%
Q4 2021+5.7%-0.5%+15.1%
Q3 2021-3.0%-1.8%-26.9%
Q2 2021+1.1%+1.4%+3.4%
Q1 2021-0.1%-3.3%-12.8%
Q4 2020-6.8%-7.5%-23.3%
Q3 2020-1.8%-12.2%+23.9%
Q2 2020-4.4%-5.4%-1.6%
Q1 2020-5.5%-11.9%+13.3%
Q4 2019+2.0%-2.1%-34.0%
Q3 2019+22.8%+27.7%+70.9%
Q2 2019-2.3%-3.9%-11.2%
Q1 2019-2.0%-1.1%-10.1%
Q4 2018+14.3%+26.2%+8.0%
Q3 2018+7.5%+3.2%+0.0%
Q2 2018-2.7%-2.7%+3.0%
Q1 2018-0.4%+2.0%+29.6%
Q4 2017+10.2%+9.7%-16.0%
Q3 2017-6.5%-2.1%+4.1%
Q2 2016+9.4%+10.1%+6.7%
Q2 2017+9.4%+10.1%+6.7%
Q1 2016-0.1%-2.9%-14.2%
Q1 2017+4.3%-4.2%-17.9%
Q4 2016+11.1%+13.3%-12.4%
Q3 2016-7.0%-1.9%-3.3%
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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