NASDAQ$CRSP
CRISPR Therapeutics AG · Q2 2023 earnings
Q2 2023 earnings · · Investor relations
Briefing
CRISPR Therapeutics reported financial results and business updates for Q2 2023.
CRISPR Therapeutics reported a net loss of $77.7 million for the second quarter of 2023, with total collaboration revenue of $70.0 million. The FDA accepted BLAs for exa-cel for severe SCD and TDT, marking significant progress towards delivering innovative gene-edited therapies.
- FDA accepted Biologics License Applications (BLAs) for exagamglogene autotemcel (exa-cel) for severe Sickle Cell Disease (SCD) and Transfusion-Dependent Beta Thalassemia (TDT).
- Enrollment and dosing are ongoing for CTX110 targeting CD19+ B-cell malignancies and CTX130 targeting CD70 for the treatment of T cell lymphomas.
- Enrollment is ongoing and dosing initiated for next-generation CAR T candidates, CTX112 targeting CD19+ B-cell malignancies and CTX131 targeting CD70+ solid tumors.
- A Phase 1/2 clinical trial of VCTX211 for the treatment of Type 1 Diabetes (T1D) continues with enrollment and dosing ongoing.
Headline financials
Revenue & EPS history
CRISPR Therapeutics · Revenue · Quarterly
$70M
Revenue by segment
CRISPR Therapeutics · $762K total across 1 segment · Q1 2022
- Grant Revenue$762K+126.1%100.0%
Forward guidance
CRISPR Therapeutics is advancing multiple clinical programs and expects to initiate a clinical trial for CTX310 this year, with plans to enter the clinic with an investigational program targeting lipoprotein (a) (Lp(a)) in the first half of 2024.
Tailwinds
- Advancing lead in vivo program, CTX310, targeting ANGPTL3, into the clinic this year.
- Progressing an investigational program targeting lipoprotein (a) (Lp(a)) and expects to enter the clinic in the first half of 2024.
- Continuing enrollment and dosing in a Phase 2 single-arm potentially registrational clinical trial of CTX110.
- Continuing enrollment and dosing in the Phase 1 COBALT-LYM trial evaluating the safety and efficacy of CTX130.
- Continuing to enroll and has initiated dosing in a Phase 1 clinical trial of CTX112.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q2 2023
+2.1%
Avg return
Earnings day
+1.3%
Avg return
5 days after
+1.4%
Avg return
30 days after
48%
19 / 40 earnings
Positive
+22.8%
Q3 2019
Best reaction
-7.7%
Q2 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +2.1% | +2.4% | +6.3% | |
| Q4 2025 | +1.2% | +10.0% | +0.9% | |
| Q3 2025 | -1.0% | -4.7% | +4.5% | |
| Q1 2025 | -0.1% | -3.2% | +7.2% | |
| Q4 2024 | -2.8% | -8.3% | -18.2% | |
| Q3 2024 | +0.3% | +2.0% | -2.1% | |
| Q2 2024 | -3.5% | -8.0% | -11.9% | |
| Q1 2024 | -3.6% | +0.2% | +4.2% | |
| Q4 2023 | +9.5% | +9.3% | -9.0% | |
| Q3 2023 | +14.9% | +4.3% | +39.5% | |
| Q2 2023 | +4.1% | -2.6% | +0.3% | |
| Q1 2023 | +13.7% | +14.5% | +12.5% | |
| Q4 2022 | -1.0% | -5.6% | -15.2% | |
| Q3 2022 | +4.5% | -2.2% | +3.8% | |
| Q2 2022 | -7.7% | -3.4% | -20.1% | |
| Q1 2022 | -1.5% | +8.8% | +53.8% | |
| Q4 2021 | +5.7% | -0.5% | +15.1% | |
| Q3 2021 | -3.0% | -1.8% | -26.9% | |
| Q2 2021 | +1.1% | +1.4% | +3.4% | |
| Q1 2021 | -0.1% | -3.3% | -12.8% | |
| Q4 2020 | -6.8% | -7.5% | -23.3% | |
| Q3 2020 | -1.8% | -12.2% | +23.9% | |
| Q2 2020 | -4.4% | -5.4% | -1.6% | |
| Q1 2020 | -5.5% | -11.9% | +13.3% | |
| Q4 2019 | +2.0% | -2.1% | -34.0% | |
| Q3 2019 | +22.8% | +27.7% | +70.9% | |
| Q2 2019 | -2.3% | -3.9% | -11.2% | |
| Q1 2019 | -2.0% | -1.1% | -10.1% | |
| Q4 2018 | +14.3% | +26.2% | +8.0% | |
| Q3 2018 | +7.5% | +3.2% | +0.0% | |
| Q2 2018 | -2.7% | -2.7% | +3.0% | |
| Q1 2018 | -0.4% | +2.0% | +29.6% | |
| Q4 2017 | +10.2% | +9.7% | -16.0% | |
| Q3 2017 | -6.5% | -2.1% | +4.1% | |
| Q2 2016 | +9.4% | +10.1% | +6.7% | |
| Q2 2017 | +9.4% | +10.1% | +6.7% | |
| Q1 2016 | -0.1% | -2.9% | -14.2% | |
| Q1 2017 | +4.3% | -4.2% | -17.9% | |
| Q4 2016 | +11.1% | +13.3% | -12.4% | |
| Q3 2016 | -7.0% | -1.9% | -3.3% | |
| Q4 2015 | — | — | — | |
| Q3 2015 | — | — | — | |
| Q2 2015 | — | — | — | |
| Q1 2015 | — | — | — |
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