NASDAQ$CRSP

CRISPR Therapeutics AG · Q4 2020 earnings

Q4 2020 earnings · · Investor relations

Briefing

CRISPR Therapeutics' fourth quarter results were negatively impacted by decreased collaboration revenue, offset by R&D and G&A expenses.

CRISPR Therapeutics reported a net loss of $107.0 million for the fourth quarter of 2020, compared to a net income of $30.5 million for the fourth quarter of 2019. The company's cash, cash equivalents, and marketable securities totaled $1,690.3 million as of December 31, 2020.

  • More than 20 patients have been dosed with CTX001™ across CLIMB-Thal-111 and CLIMB-SCD-121 to date; completion of enrollment in both trials is expected in 2021
  • Additional data from CTX110™ trial expected to report in 2021, along with top-line data from CTX120™ and CTX130™
  • Total collaboration revenue was $0.2 million for the fourth quarter of 2020 compared to $77.0 million for fourth quarter of 2019
  • Net loss was $107.0 million for the fourth quarter of 2020 compared to income of $30.5 million for the fourth quarter of 2019

Headline financials

Total Revenue

$370K

Previous: $77M-99.5%
EPS (adj)

-$1.50

Previous: $0.51-394.1%
Capital Expenditures

$6.24M

Previous: $952K+555.4%
Free Cash Flow

-$87.5M

Previous: $2.42M-3707.7%
Net Income

-$107M

Previous: $30.5M-450.8%
Operating Income

-$108M

Previous: $11M-1081.2%
Gross Profit

-$82.2M

Previous: $28.3M-390.8%
Cash & Equivalents

$1.17B

Previous: $944M+23.8%
Total Assets

$1.83B

Previous: $1.07B+71.4%
Stock-Based Comp

$18.9M

Previous: $11.9M+59.7%

Revenue & EPS history

CRISPR Therapeutics · Revenue · Quarterly

$370K

Q4 2020-99.5%vs Q4 2019
Beat estimate in 11 of 16 quarters(69%)
ActualEstimate

Revenue by segment

CRISPR Therapeutics · $176K total across 1 segment · Q4 2020

  • Grant Revenue
    $176K

Forward guidance

CRISPR Therapeutics anticipates completing enrollment in CTX001 clinical trials, providing data updates on allogeneic CAR-T programs, bringing the large-scale manufacturing facility online, and building commercial infrastructure in 2021.

Tailwinds

  • Complete enrollment in the CTX001 clinical trials
  • Provide data updates on our three clinical allogeneic CAR-T programs
  • Make meaningful progress in bringing our large-scale manufacturing facility online
  • Building our commercial infrastructure
  • Advance programs as we enter a new phase of growth for the company

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2020

Historical avgQ4 2020

+2.1%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+1.4%

Avg return

30 days after

48%

19 / 40 earnings

Positive

+22.8%

Q3 2019

Best reaction

-7.7%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.1%+2.4%+6.3%
Q4 2025+1.2%+10.0%+0.9%
Q3 2025-1.0%-4.7%+4.5%
Q1 2025-0.1%-3.2%+7.2%
Q4 2024-2.8%-8.3%-18.2%
Q3 2024+0.3%+2.0%-2.1%
Q2 2024-3.5%-8.0%-11.9%
Q1 2024-3.6%+0.2%+4.2%
Q4 2023+9.5%+9.3%-9.0%
Q3 2023+14.9%+4.3%+39.5%
Q2 2023+4.1%-2.6%+0.3%
Q1 2023+13.7%+14.5%+12.5%
Q4 2022-1.0%-5.6%-15.2%
Q3 2022+4.5%-2.2%+3.8%
Q2 2022-7.7%-3.4%-20.1%
Q1 2022-1.5%+8.8%+53.8%
Q4 2021+5.7%-0.5%+15.1%
Q3 2021-3.0%-1.8%-26.9%
Q2 2021+1.1%+1.4%+3.4%
Q1 2021-0.1%-3.3%-12.8%
Q4 2020-6.8%-7.5%-23.3%
Q3 2020-1.8%-12.2%+23.9%
Q2 2020-4.4%-5.4%-1.6%
Q1 2020-5.5%-11.9%+13.3%
Q4 2019+2.0%-2.1%-34.0%
Q3 2019+22.8%+27.7%+70.9%
Q2 2019-2.3%-3.9%-11.2%
Q1 2019-2.0%-1.1%-10.1%
Q4 2018+14.3%+26.2%+8.0%
Q3 2018+7.5%+3.2%+0.0%
Q2 2018-2.7%-2.7%+3.0%
Q1 2018-0.4%+2.0%+29.6%
Q4 2017+10.2%+9.7%-16.0%
Q3 2017-6.5%-2.1%+4.1%
Q2 2016+9.4%+10.1%+6.7%
Q2 2017+9.4%+10.1%+6.7%
Q1 2016-0.1%-2.9%-14.2%
Q1 2017+4.3%-4.2%-17.9%
Q4 2016+11.1%+13.3%-12.4%
Q3 2016-7.0%-1.9%-3.3%
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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