NASDAQ$CRSP
CRISPR Therapeutics AG · Q1 2022 earnings
Q1 2022 earnings · · Investor relations
Briefing
Reported financial results for the first quarter ended March 31, 2022.
CRISPR Therapeutics reported its Q1 2022 financial results, with a cash position of $2,221.3 million. The company's total collaboration revenue was $0.2 million. R&D expenses increased to $118.2 million, and G&A expenses were $28.0 million. The net loss for the quarter was $179.2 million.
- More than 75 patients dosed with CTX001 across CLIMB-Thal-111 and CLIMB-SCD-121 to date; planned global regulatory submissions on track for late 2022.
- Initiated two new CTX001 Phase 3 clinical trials in pediatric patients with TDT and SCD.
- Enrollment and dosing ongoing for CTX110, targeting CD19+ B-cell malignancies; additional data expected to report in 2022.
- Updates from ongoing CTX120 and CTX130 clinical trials anticipated in 1H2022.
Headline financials
Revenue & EPS history
CRISPR Therapeutics · Revenue · Quarterly
$940K
Revenue by segment
CRISPR Therapeutics · $762K total across 1 segment · Q1 2022
- Grant Revenue$762K+126.1%100.0%
Forward guidance
CRISPR Therapeutics anticipates important company milestones in 2022. Alongside partner Vertex, they remain on track to submit global regulatory filings for CTX001 in late 2022. They are also advancing wholly-owned immuno-oncology pipeline, with new updates expected this year.
Tailwinds
- Global regulatory filings for CTX001 in late 2022 are on track.
- Advancing wholly-owned immuno-oncology pipeline.
- New updates expected this year.
- Enrollment and dosing continues in the Phase 1 clinical trial of VCTX210 for T1D with partner, ViaCyte.
- Well positioned and well capitalized to advance pipeline and platform to develop transformative medicines for patients suffering from serious diseases.
Headwinds
- Potential for initial and preliminary data from any clinical trial and initial data from a limited number of patients not to be indicative of final trial results.
- Potential that clinical trial results may not be favorable.
- Future competitive or other market factors may adversely affect the commercial potential for CRISPR Therapeutics’ product candidates.
- Uncertainties about regulatory approvals to conduct trials or to market products.
- Potential impacts due to the coronavirus pandemic such as (x) delays in regulatory review, manufacturing and supply chain interruptions, adverse effects on healthcare systems and disruption of the global economy; (y) the timing and progress of clinical trials, preclinical studies and other research and development activities; and (z) the overall impact of the coronavirus pandemic on its business, financial condition and results of operations.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2022
+2.1%
Avg return
Earnings day
+1.3%
Avg return
5 days after
+1.4%
Avg return
30 days after
48%
19 / 40 earnings
Positive
+22.8%
Q3 2019
Best reaction
-7.7%
Q2 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +2.1% | +2.4% | +6.3% | |
| Q4 2025 | +1.2% | +10.0% | +0.9% | |
| Q3 2025 | -1.0% | -4.7% | +4.5% | |
| Q1 2025 | -0.1% | -3.2% | +7.2% | |
| Q4 2024 | -2.8% | -8.3% | -18.2% | |
| Q3 2024 | +0.3% | +2.0% | -2.1% | |
| Q2 2024 | -3.5% | -8.0% | -11.9% | |
| Q1 2024 | -3.6% | +0.2% | +4.2% | |
| Q4 2023 | +9.5% | +9.3% | -9.0% | |
| Q3 2023 | +14.9% | +4.3% | +39.5% | |
| Q2 2023 | +4.1% | -2.6% | +0.3% | |
| Q1 2023 | +13.7% | +14.5% | +12.5% | |
| Q4 2022 | -1.0% | -5.6% | -15.2% | |
| Q3 2022 | +4.5% | -2.2% | +3.8% | |
| Q2 2022 | -7.7% | -3.4% | -20.1% | |
| Q1 2022 | -1.5% | +8.8% | +53.8% | |
| Q4 2021 | +5.7% | -0.5% | +15.1% | |
| Q3 2021 | -3.0% | -1.8% | -26.9% | |
| Q2 2021 | +1.1% | +1.4% | +3.4% | |
| Q1 2021 | -0.1% | -3.3% | -12.8% | |
| Q4 2020 | -6.8% | -7.5% | -23.3% | |
| Q3 2020 | -1.8% | -12.2% | +23.9% | |
| Q2 2020 | -4.4% | -5.4% | -1.6% | |
| Q1 2020 | -5.5% | -11.9% | +13.3% | |
| Q4 2019 | +2.0% | -2.1% | -34.0% | |
| Q3 2019 | +22.8% | +27.7% | +70.9% | |
| Q2 2019 | -2.3% | -3.9% | -11.2% | |
| Q1 2019 | -2.0% | -1.1% | -10.1% | |
| Q4 2018 | +14.3% | +26.2% | +8.0% | |
| Q3 2018 | +7.5% | +3.2% | +0.0% | |
| Q2 2018 | -2.7% | -2.7% | +3.0% | |
| Q1 2018 | -0.4% | +2.0% | +29.6% | |
| Q4 2017 | +10.2% | +9.7% | -16.0% | |
| Q3 2017 | -6.5% | -2.1% | +4.1% | |
| Q2 2016 | +9.4% | +10.1% | +6.7% | |
| Q2 2017 | +9.4% | +10.1% | +6.7% | |
| Q1 2016 | -0.1% | -2.9% | -14.2% | |
| Q1 2017 | +4.3% | -4.2% | -17.9% | |
| Q4 2016 | +11.1% | +13.3% | -12.4% | |
| Q3 2016 | -7.0% | -1.9% | -3.3% | |
| Q4 2015 | — | — | — | |
| Q3 2015 | — | — | — | |
| Q2 2015 | — | — | — | |
| Q1 2015 | — | — | — |
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