NASDAQ$CRSP

CRISPR Therapeutics AG · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

CRISPR Therapeutics reported financial results for the third quarter ended September 30, 2021.

CRISPR Therapeutics reported a net loss of $127.2 million for the third quarter of 2021, compared to a net loss of $92.4 million for the third quarter of 2020. Total collaboration revenue was $0.3 million for the third quarter of 2021, compared to $0.1 million for the third quarter of 2020. Cash, cash equivalents and marketable securities were $2,477.4 million as of September 30, 2021, compared to $2,589.4 million as of June 30, 2021.

  • Target enrollment achieved in CTX001 clinical trials for beta thalassemia (TDT) and sickle cell disease (SCD); regulatory submissions planned for late 2022.
  • Positive results reported from the Phase 1 CARBON clinical trial evaluating CTX110™ for CD19+ B-cell malignancies; enrollment continues, with a potential registrational trial expected to start in Q1 2022.
  • Consolidation dosing protocols are being implemented for CTX120™ and CTX130™ clinical trials; enrollment continues, with top-line data expected in 1H 2022.
  • Regenerative medicine and in vivo programs continue to progress as planned.

Headline financials

Total Revenue

$824K

Previous: $148K+456.8%
EPS (adj)

-$1.67

Previous: -$1.32-26.5%
Capital Expenditures

-$72.5M

Previous: -$12.1M-498.4%
Free Cash Flow

-$200M

Previous: -$105M-91.0%
Net Income

-$127M

Previous: -$92.4M-37.6%
Operating Income

-$129M

Previous: -$92.4M-39.4%
Gross Profit

-$22.1M

Previous: -$70.9M+68.8%
Cash & Equivalents

$1.01B

Previous: $1.04B-2.9%
Total Assets

$2.82B

Previous: $1.49B+90.0%
Stock-Based Comp

$26.2M

Previous: $17.2M+52.0%

Revenue & EPS history

CRISPR Therapeutics · Revenue · Quarterly

$824K

Q3 2021+456.8%vs Q3 2020
Beat estimate in 10 of 16 quarters(63%)
ActualEstimate

Revenue by segment

CRISPR Therapeutics · $762K total across 1 segment · Q1 2022

  • Grant Revenue
    $762K+126.1%

Forward guidance

CRISPR Therapeutics continues to advance its pipeline and expects to move multiple programs utilizing in vivo approaches into the clinic in the next 18 to 24 months.

Tailwinds

  • Planned regulatory submissions for CTX001 in late 2022.
  • Potential registrational trial for CTX110 incorporating consolidation dosing expected to initiate in Q1 2022.
  • Top-line data expected to report in 1H 2022 for CTX120™ and CTX130™ clinical trials.
  • Phase 1/2 trial of allogeneic stem cell-derived therapy for Type 1 diabetes initiation remains on track for 2021.
  • Multiple programs utilizing in vivo approaches expected to move into the clinic in the next 18 to 24 months.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

+2.1%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+1.4%

Avg return

30 days after

48%

19 / 40 earnings

Positive

+22.8%

Q3 2019

Best reaction

-7.7%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.1%+2.4%+6.3%
Q4 2025+1.2%+10.0%+0.9%
Q3 2025-1.0%-4.7%+4.5%
Q1 2025-0.1%-3.2%+7.2%
Q4 2024-2.8%-8.3%-18.2%
Q3 2024+0.3%+2.0%-2.1%
Q2 2024-3.5%-8.0%-11.9%
Q1 2024-3.6%+0.2%+4.2%
Q4 2023+9.5%+9.3%-9.0%
Q3 2023+14.9%+4.3%+39.5%
Q2 2023+4.1%-2.6%+0.3%
Q1 2023+13.7%+14.5%+12.5%
Q4 2022-1.0%-5.6%-15.2%
Q3 2022+4.5%-2.2%+3.8%
Q2 2022-7.7%-3.4%-20.1%
Q1 2022-1.5%+8.8%+53.8%
Q4 2021+5.7%-0.5%+15.1%
Q3 2021-3.0%-1.8%-26.9%
Q2 2021+1.1%+1.4%+3.4%
Q1 2021-0.1%-3.3%-12.8%
Q4 2020-6.8%-7.5%-23.3%
Q3 2020-1.8%-12.2%+23.9%
Q2 2020-4.4%-5.4%-1.6%
Q1 2020-5.5%-11.9%+13.3%
Q4 2019+2.0%-2.1%-34.0%
Q3 2019+22.8%+27.7%+70.9%
Q2 2019-2.3%-3.9%-11.2%
Q1 2019-2.0%-1.1%-10.1%
Q4 2018+14.3%+26.2%+8.0%
Q3 2018+7.5%+3.2%+0.0%
Q2 2018-2.7%-2.7%+3.0%
Q1 2018-0.4%+2.0%+29.6%
Q4 2017+10.2%+9.7%-16.0%
Q3 2017-6.5%-2.1%+4.1%
Q2 2016+9.4%+10.1%+6.7%
Q2 2017+9.4%+10.1%+6.7%
Q1 2016-0.1%-2.9%-14.2%
Q1 2017+4.3%-4.2%-17.9%
Q4 2016+11.1%+13.3%-12.4%
Q3 2016-7.0%-1.9%-3.3%
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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