NASDAQ$CRSP

CRISPR Therapeutics AG · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Reported financial results for the first quarter ended March 31, 2024, and provided a business update.

CRISPR Therapeutics reported its Q1 2024 financial results, highlighted by a strong cash position of approximately $2.1 billion. The company is advancing its portfolio of clinical trials and nominated additional in vivo programs.

  • More than 25 authorized treatment centers (ATCs) activated globally for CASGEVY™.
  • Clinical trials ongoing for next generation CAR T product candidates, CTX112™ and CTX131™.
  • Clinical trials ongoing for in vivo gene editing product candidates, CTX310™ and CTX320™.
  • Expanded pipeline with new pre-clinical programs utilizing lipid nanoparticle (LNP) mediated delivery to the liver for refractory hypertension and acute hepatic porphyria.

Headline financials

Total Revenue

$504K

Previous: $100M-99.5%
EPS

-$1.43

Previous: -$0.67-113.4%
R&D Expenses

$76.2M

No prior period
G&A Expenses

$18M

No prior period
Collaboration Expense

$47M

No prior period
Marketable Securities

$1.61B

No prior period
Working Capital

$1.85B

No prior period
Total Shareholders' Equity

$1.93B

No prior period
Capital Expenditures

-$721K

Previous: -$3.06M+76.4%
Free Cash Flow

-$117M

Previous: -$56.1M-109.0%
Net Income

-$117M

Previous: -$53.1M-119.7%
Operating Income

-$141M

Previous: -$64.5M-118.0%
R&D Expense

$76.2M

No prior period
Stock-Based Comp

$19.4M

Previous: $20.9M-7.0%

Revenue & EPS history

CRISPR Therapeutics · Revenue · Quarterly

$504K

Q1 2024-99.5%vs Q1 2023
Beat estimate in 5 of 15 quarters(33%)
ActualEstimate

Revenue by segment

CRISPR Therapeutics · $762K total across 1 segment · Q1 2022

  • Grant Revenue
    $762K+126.1%

Forward guidance

CRISPR Therapeutics expects to broaden the number of patients that could potentially benefit from transformative gene-editing based therapies with multiple data read-outs in the next 12-18 months and to initiate clinical trials for CTX340 and CTX450 in the second half of 2025.

Tailwinds

  • Advancing portfolio of clinical trials across oncology, autoimmune, diabetes and cardiovascular indications.
  • Nominating additional in vivo programs targeting both rare and common diseases to portfolio based on promising pre-clinical data.
  • Initiating a clinical trial for CTX112 in systemic lupus erythematosus (SLE) in the first half of this year.
  • Initiating a clinical trial for CTX131 in hematologic malignancies in the first half of this year.
  • Expanding the liver-targeted in vivo pipeline.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+2.1%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+1.4%

Avg return

30 days after

48%

19 / 40 earnings

Positive

+22.8%

Q3 2019

Best reaction

-7.7%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.1%+2.4%+6.3%
Q4 2025+1.2%+10.0%+0.9%
Q3 2025-1.0%-4.7%+4.5%
Q1 2025-0.1%-3.2%+7.2%
Q4 2024-2.8%-8.3%-18.2%
Q3 2024+0.3%+2.0%-2.1%
Q2 2024-3.5%-8.0%-11.9%
Q1 2024-3.6%+0.2%+4.2%
Q4 2023+9.5%+9.3%-9.0%
Q3 2023+14.9%+4.3%+39.5%
Q2 2023+4.1%-2.6%+0.3%
Q1 2023+13.7%+14.5%+12.5%
Q4 2022-1.0%-5.6%-15.2%
Q3 2022+4.5%-2.2%+3.8%
Q2 2022-7.7%-3.4%-20.1%
Q1 2022-1.5%+8.8%+53.8%
Q4 2021+5.7%-0.5%+15.1%
Q3 2021-3.0%-1.8%-26.9%
Q2 2021+1.1%+1.4%+3.4%
Q1 2021-0.1%-3.3%-12.8%
Q4 2020-6.8%-7.5%-23.3%
Q3 2020-1.8%-12.2%+23.9%
Q2 2020-4.4%-5.4%-1.6%
Q1 2020-5.5%-11.9%+13.3%
Q4 2019+2.0%-2.1%-34.0%
Q3 2019+22.8%+27.7%+70.9%
Q2 2019-2.3%-3.9%-11.2%
Q1 2019-2.0%-1.1%-10.1%
Q4 2018+14.3%+26.2%+8.0%
Q3 2018+7.5%+3.2%+0.0%
Q2 2018-2.7%-2.7%+3.0%
Q1 2018-0.4%+2.0%+29.6%
Q4 2017+10.2%+9.7%-16.0%
Q3 2017-6.5%-2.1%+4.1%
Q2 2016+9.4%+10.1%+6.7%
Q2 2017+9.4%+10.1%+6.7%
Q1 2016-0.1%-2.9%-14.2%
Q1 2017+4.3%-4.2%-17.9%
Q4 2016+11.1%+13.3%-12.4%
Q3 2016-7.0%-1.9%-3.3%
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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