NASDAQ$GERN
Geron Corp · Q4 2024 earnings
Q4 2024 earnings · · Before market open · Investor relations
Briefing
Reported financial results for the fourth quarter and full year 2024 and recent business highlights.
Geron Corporation reported Q4 2024 financial results, achieving $47.5 million in RYTELO net product revenue and ending the year with a strong cash position. The company expects to reach profitability without additional financing if current sales and operating expense expectations are met. Continued progress in development efforts for relapsed/refractory myelofibrosis could potentially double commercial opportunity.
- Achieved $47.5 million in RYTELO net product revenue in Q4 2024.
- Received positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommending approval of RYTELO.
- Achieved approximately 80% enrollment in the Phase 3 IMpactMF trial.
- Presented new data at the 66th American Society for Hematology (ASH) Annual Meeting.
Headline financials
Revenue & EPS history
Geron · Revenue · Quarterly
$47.5M
Revenue by segment
Geron · $164K total across 1 segment · Q3 2023
- Royalties$164K—100.0%
Forward guidance
For fiscal year 2025, Geron expects total operating expenses to be in the range of approximately $270 million to $285 million and expects to reach profitability without additional financing if current internal sales and operating expense expectations are met.
Tailwinds
- Expects to reach profitability without additional financing if current internal sales and operating expense expectations are met.
- Existing cash, cash equivalents, and marketable securities, together with anticipated net revenues from U.S. sales of RYTELO, will be sufficient to fund projected operating requirements for the foreseeable future.
- Continued execution on U.S. commercial launch of RYTELO.
- Received positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommending approval of RYTELO.
- Phase 3 IMpactMF trial evaluating imetelstat in patients with relapsed/refractory myelofibrosis (R/R MF) is ongoing.
Headwinds
- Total operating expenses for fiscal year 2025 are expected to be in the range of approximately $270 million to $285 million.
- The interim analysis for overall survival in the Phase 3 IMpactMF trial may occur in the second half of 2026.
- The final analysis for overall survival in the Phase 3 IMpactMF trial may occur in the second half of 2028.
- Potential delays and other adverse impacts caused by enrollment, clinical, safety, efficacy, technical, scientific, intellectual property, manufacturing and regulatory challenges.
- Risks related to commercializing RYTELO (imetelstat) for the treatment of certain patients with lower-risk MDS with transfusion dependent anemia.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2024
+0.6%
Avg return
Earnings day
-1.3%
Avg return
5 days after
+4.2%
Avg return
30 days after
42%
27 / 64 earnings
Positive
+35.3%
Q4 2013
Best reaction
-32.1%
Q4 2024
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -4.2% | -15.8% | -29.1% | |
| Q4 2025 | -11.3% | -20.5% | -28.2% | |
| Q3 2025 | -4.5% | +0.9% | +13.9% | |
| Q1 2025 | -0.8% | -3.0% | +21.2% | |
| Q4 2024 | -32.1% | -27.8% | -30.4% | |
| Q3 2024 | -0.5% | -7.0% | -8.0% | |
| Q2 2024 | +3.1% | +0.2% | -6.8% | |
| Q1 2024 | -3.7% | -5.1% | -13.0% | |
| Q4 2023 | -3.4% | +0.5% | +59.4% | |
| Q3 2023 | +2.6% | -1.0% | +3.1% | |
| Q2 2023 | -7.5% | -7.5% | -22.5% | |
| Q1 2023 | +9.9% | +6.0% | +27.7% | |
| Q4 2022 | -3.4% | -10.7% | -24.8% | |
| Q3 2022 | -2.3% | +0.9% | +7.0% | |
| Q2 2022 | +8.3% | +2.3% | +22.1% | |
| Q1 2022 | +13.8% | +11.5% | +8.5% | |
| Q4 2021 | +0.9% | -3.7% | +46.3% | |
| Q3 2021 | -9.3% | -8.7% | -21.5% | |
| Q2 2021 | +4.9% | +4.1% | +11.5% | |
| Q1 2021 | +4.5% | +7.5% | +12.8% | |
| Q4 2020 | -6.0% | -3.3% | -19.1% | |
| Q3 2020 | -4.8% | -0.5% | -2.7% | |
| Q2 2020 | -2.3% | -7.0% | +6.4% | |
| Q1 2020 | -1.8% | +0.0% | +17.7% | |
| Q4 2019 | -6.8% | -7.8% | +7.8% | |
| Q3 2019 | +0.7% | +0.0% | +2.0% | |
| Q2 2019 | -3.3% | -0.8% | +16.7% | |
| Q1 2019 | -0.6% | -3.3% | -19.9% | |
| Q4 2018 | +0.7% | +7.7% | +27.3% | |
| Q3 2018 | +9.2% | +7.8% | +5.2% | |
| Q2 2018 | +4.5% | +4.8% | +63.6% | |
| Q1 2018 | -9.9% | -10.9% | -2.1% | |
| Q4 2017 | +24.7% | +43.4% | +10.6% | |
| Q3 2017 | -8.9% | -8.4% | -14.2% | |
| Q2 2017 | -7.1% | -8.4% | -5.8% | |
| Q1 2017 | +0.8% | +11.7% | +4.7% | |
| Q4 2016 | +2.3% | -0.9% | +5.6% | |
| Q3 2016 | +2.7% | +2.2% | +8.6% | |
| Q2 2016 | -0.4% | +0.0% | +1.1% | |
| Q1 2016 | -2.2% | — | — | |
| Q4 2015 | -4.2% | — | — | |
| Q3 2015 | +3.4% | — | — | |
| Q2 2015 | -7.8% | — | — | |
| Q1 2015 | +3.1% | — | — | |
| Q4 2014 | -7.0% | — | — | |
| Q3 2014 | +20.2% | — | — | |
| Q2 2014 | -5.3% | — | — | |
| Q1 2014 | -6.4% | — | — | |
| Q4 2013 | +35.3% | — | — | |
| Q3 2013 | +28.2% | — | — | |
| Q2 2013 | +14.6% | — | — | |
| Q1 2013 | -1.8% | — | — | |
| Q4 2012 | -5.1% | — | — | |
| Q3 2012 | -1.5% | — | — | |
| Q2 2012 | +3.8% | — | — | |
| Q1 2012 | -0.7% | — | — | |
| Q4 2011 | -0.6% | — | — | |
| Q3 2011 | +4.2% | — | — | |
| Q2 2011 | -15.6% | — | — | |
| Q1 2011 | +0.0% | — | — | |
| Q4 2010 | +1.7% | — | — | |
| Q3 2010 | -4.5% | — | — | |
| Q2 2010 | +26.4% | — | — | |
| Q1 2010 | +3.2% | — | — |
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