NASDAQ$GERN
Geron Corp · Q4 2021 earnings
Q4 2021 earnings · · Investor relations
Briefing
Geron reported fourth quarter and full year 2021 financial results, highlighting progress in imetelstat development and upcoming milestones.
Geron Corporation reported a net loss of $32.0 million for the fourth quarter of 2021, compared to a net loss of $23.8 million for the same period in 2020. The company ended the year with $212.7 million in cash and marketable securities, expected to fund operations through Q1 2023. Key milestones include anticipated top-line results from the IMerge Phase 3 trial in early January 2023 and a planned interim analysis from the IMpactMF trial in 2024.
- Net loss for Q4 2021 was $32.0 million, or $0.10 per share, compared to $23.8 million, or $0.07 per share, for Q4 2020.
- Revenues for Q4 2021 were $1.0 million compared to $50,000 for the same period in 2020.
- The company ended 2021 with $212.7 million in cash and marketable securities.
- Top-line results from IMerge Phase 3 trial in lower risk MDS are expected in early January 2023.
Headline financials
Revenue & EPS history
Geron · Revenue · Quarterly
$1.04M
Revenue by segment
Geron · $164K total across 1 segment · Q3 2023
- Royalties$164K—100.0%
Forward guidance
Geron expects total operating expenses for fiscal year 2022 to be in the range of $155 million to $165 million (GAAP) and $140 million to $150 million (non-GAAP).
Tailwinds
- Preparatory activities for top-line results in lower risk MDS.
- NDA and commercial readiness activities.
- Two ongoing Phase 3 clinical trials and new clinical studies expanding the pipeline.
- Finalizing validation batches of imetelstat at contract manufacturers.
- Projected increases in headcount.
Headwinds
- Potential delays and adverse impacts caused by the COVID-19 pandemic and/or the Russia/Ukraine conflict.
- Enrollment, clinical, safety, efficacy, technical, scientific, intellectual property, manufacturing and regulatory challenges.
- Whether regulatory authorities permit the further development of imetelstat on a timely basis, or at all, without any clinical holds.
- Whether imetelstat is demonstrated to be safe and efficacious in IMerge Phase 3 and IMpactMF to enable regulatory approval.
- Whether any future efficacy or safety results may cause the benefit-risk profile of imetelstat to become unacceptable.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2021
+0.6%
Avg return
Earnings day
-1.3%
Avg return
5 days after
+4.2%
Avg return
30 days after
42%
27 / 64 earnings
Positive
+35.3%
Q4 2013
Best reaction
-32.1%
Q4 2024
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -4.2% | -15.8% | -29.1% | |
| Q4 2025 | -11.3% | -20.5% | -28.2% | |
| Q3 2025 | -4.5% | +0.9% | +13.9% | |
| Q1 2025 | -0.8% | -3.0% | +21.2% | |
| Q4 2024 | -32.1% | -27.8% | -30.4% | |
| Q3 2024 | -0.5% | -7.0% | -8.0% | |
| Q2 2024 | +3.1% | +0.2% | -6.8% | |
| Q1 2024 | -3.7% | -5.1% | -13.0% | |
| Q4 2023 | -3.4% | +0.5% | +59.4% | |
| Q3 2023 | +2.6% | -1.0% | +3.1% | |
| Q2 2023 | -7.5% | -7.5% | -22.5% | |
| Q1 2023 | +9.9% | +6.0% | +27.7% | |
| Q4 2022 | -3.4% | -10.7% | -24.8% | |
| Q3 2022 | -2.3% | +0.9% | +7.0% | |
| Q2 2022 | +8.3% | +2.3% | +22.1% | |
| Q1 2022 | +13.8% | +11.5% | +8.5% | |
| Q4 2021 | +0.9% | -3.7% | +46.3% | |
| Q3 2021 | -9.3% | -8.7% | -21.5% | |
| Q2 2021 | +4.9% | +4.1% | +11.5% | |
| Q1 2021 | +4.5% | +7.5% | +12.8% | |
| Q4 2020 | -6.0% | -3.3% | -19.1% | |
| Q3 2020 | -4.8% | -0.5% | -2.7% | |
| Q2 2020 | -2.3% | -7.0% | +6.4% | |
| Q1 2020 | -1.8% | +0.0% | +17.7% | |
| Q4 2019 | -6.8% | -7.8% | +7.8% | |
| Q3 2019 | +0.7% | +0.0% | +2.0% | |
| Q2 2019 | -3.3% | -0.8% | +16.7% | |
| Q1 2019 | -0.6% | -3.3% | -19.9% | |
| Q4 2018 | +0.7% | +7.7% | +27.3% | |
| Q3 2018 | +9.2% | +7.8% | +5.2% | |
| Q2 2018 | +4.5% | +4.8% | +63.6% | |
| Q1 2018 | -9.9% | -10.9% | -2.1% | |
| Q4 2017 | +24.7% | +43.4% | +10.6% | |
| Q3 2017 | -8.9% | -8.4% | -14.2% | |
| Q2 2017 | -7.1% | -8.4% | -5.8% | |
| Q1 2017 | +0.8% | +11.7% | +4.7% | |
| Q4 2016 | +2.3% | -0.9% | +5.6% | |
| Q3 2016 | +2.7% | +2.2% | +8.6% | |
| Q2 2016 | -0.4% | +0.0% | +1.1% | |
| Q1 2016 | -2.2% | — | — | |
| Q4 2015 | -4.2% | — | — | |
| Q3 2015 | +3.4% | — | — | |
| Q2 2015 | -7.8% | — | — | |
| Q1 2015 | +3.1% | — | — | |
| Q4 2014 | -7.0% | — | — | |
| Q3 2014 | +20.2% | — | — | |
| Q2 2014 | -5.3% | — | — | |
| Q1 2014 | -6.4% | — | — | |
| Q4 2013 | +35.3% | — | — | |
| Q3 2013 | +28.2% | — | — | |
| Q2 2013 | +14.6% | — | — | |
| Q1 2013 | -1.8% | — | — | |
| Q4 2012 | -5.1% | — | — | |
| Q3 2012 | -1.5% | — | — | |
| Q2 2012 | +3.8% | — | — | |
| Q1 2012 | -0.7% | — | — | |
| Q4 2011 | -0.6% | — | — | |
| Q3 2011 | +4.2% | — | — | |
| Q2 2011 | -15.6% | — | — | |
| Q1 2011 | +0.0% | — | — | |
| Q4 2010 | +1.7% | — | — | |
| Q3 2010 | -4.5% | — | — | |
| Q2 2010 | +26.4% | — | — | |
| Q1 2010 | +3.2% | — | — |
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