NASDAQ$EXAS

Exact Sciences Corp · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Exact Sciences reported strong revenue growth but faced significant impairment charges leading to a large net loss.

Exact Sciences achieved 10% YoY revenue growth in Q4 2024, reaching $713.42M. Screening revenue grew by 14%, while Precision Oncology revenue remained flat. However, an $838M impairment charge led to a substantial net loss of $864.59M, significantly higher than the prior year's loss of $49.77M. Adjusted EBITDA improved to $75.38M with an 11% margin.

  • Total revenue grew 10% YoY to $713.42M.
  • Screening revenue increased by 14%, driven by Cologuard.
  • Net loss widened to $864.59M due to an $838M impairment charge.
  • Adjusted EBITDA rose to $75.38M with an 11% margin.

Headline financials

Total Revenue

$713M

Previous: $647M+10.3%
EPS (adj)

-$0.06

Previous: -$0.27+77.8%
Adjusted EBITDA

$75.4M

Previous: $49.7M+51.7%
Adjusted EBITDA Margin

12.0%

No prior period
Net Income

-$865M

Previous: -$49.8M-1637.3%
Operating Income

-$876M

Previous: -$67.8M-1191.8%
Gross Profit

$429M

Previous: $454M-5.4%

Revenue & EPS history

Exact Sciences · Revenue · Quarterly

$713M

Q4 2024+10.3%vs Q4 2023
Beat estimate in 15 of 16 quarters(94%)
ActualEstimate

Revenue by segment

Exact Sciences · $628M total across 2 segments · Q3 2023

  • Screening
    $472M+30.8%
  • Precision Oncology
    $156M+3.2%

Forward guidance

Exact Sciences expects revenue growth between 9%-12% in 2025, driven by new product launches and expanded screening adoption. Adjusted EBITDA is projected to improve, indicating better profitability.

Tailwinds

  • Full-year 2025 revenue guidance of $3.03B - $3.09B (+9% - 12% YoY).
  • Screening revenue expected to grow to $2.35B - $2.39B.
  • Precision Oncology revenue forecasted at $675M - $695M.
  • Adjusted EBITDA projected to rise to $410M - $440M.
  • Launch of Cologuard Plus, Oncodetect, and Cancerguard expected in 2025.

Headwinds

  • Large impairment charges could impact profitability in the near term.
  • Precision Oncology revenue showed minimal growth in Q4 2024.
  • Continued net losses despite revenue growth.
  • High operating expenses, including R&D and marketing investments.
  • Potential reimbursement and regulatory challenges for new test launches.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.8%

Avg return

Earnings day

+2.3%

Avg return

5 days after

+3.4%

Avg return

30 days after

55%

35 / 64 earnings

Positive

+35.0%

Q2 2016

Best reaction

-27.1%

Q3 2010

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026
Q4 2025+0.0%+0.0%+0.7%
Q3 2025+3.8%-1.2%+51.0%
Q2 2025-8.2%-11.0%+14.7%
Q1 2025+9.1%+13.0%+19.3%
Q4 2024-1.9%-0.6%-9.6%
Q3 2024-23.1%-27.6%-12.0%
Q2 2024+24.3%+19.7%+32.4%
Q1 2024-11.8%-9.5%-30.1%
Q4 2023-5.2%-8.3%-1.0%
Q3 2023+1.4%+5.9%+8.8%
Q2 2023-12.7%-12.6%-14.2%
Q1 2023+14.9%+15.5%+32.2%
Q4 2022+1.9%-5.4%+3.0%
Q3 2022+13.8%+23.9%+40.4%
Q2 2022+0.8%-0.3%-23.2%
Q1 2022-0.2%-12.1%-20.4%
Q4 2021-6.9%+5.7%-9.5%
Q3 2021-3.2%+3.3%-17.3%
Q2 2021-0.0%-3.2%-7.2%
Q1 2021-11.9%-16.8%-14.0%
Q4 2020-9.0%-4.6%-17.4%
Q3 2020+19.7%+16.2%+8.7%
Q2 2020+0.1%-1.8%-22.7%
Q1 2020+6.3%+7.7%+11.3%
Q4 2019-1.1%+1.4%-46.8%
Q3 2019-9.5%-3.1%-12.2%
Q2 2019-0.0%-2.4%+1.9%
Q1 2019-0.9%+6.7%+3.5%
Q4 2018+10.1%+10.7%+6.4%
Q3 2018+15.5%+20.7%+23.3%
Q2 2018-11.7%-12.9%+28.1%
Q1 2018+14.9%+10.5%+14.5%
Q4 2017-9.2%-4.9%-5.4%
Q3 2017+7.5%+10.8%+13.0%
Q2 2017+0.5%+0.1%+4.2%
Q1 2017+26.1%+30.1%+40.0%
Q4 2016+14.0%+7.6%+2.9%
Q3 2016-22.1%-20.5%-19.3%
Q2 2016+35.0%+39.5%+52.9%
Q1 2016-16.9%
Q4 2015-9.5%
Q3 2015+1.0%
Q2 2015-8.9%
Q1 2015+6.2%
Q4 2014-0.8%
Q3 2014+6.1%
Q2 2014+1.1%
Q1 2014+0.7%
Q4 2013+10.5%
Q3 2013-1.0%
Q2 2013-8.0%
Q1 2013+2.4%
Q4 2012+2.7%
Q3 2012+5.4%
Q2 2012+5.4%
Q1 2012+1.4%
Q4 2011+4.6%
Q3 2011-4.1%
Q2 2011-6.7%
Q1 2011+1.6%
Q4 2010+2.8%
Q3 2010-27.1%
Q2 2010+3.3%
Q1 2010+6.0%

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