NASDAQ$TARS

Tarsus Pharmaceuticals Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Tarsus Pharmaceuticals reported full-year 2021 financial results and business achievements.

Tarsus Pharmaceuticals reported a full-year net loss of $13.8 million, with research and development expenses at $41.7 million and general and administrative expenses at $25.4 million. The company's cash, cash equivalents, and marketable securities totaled $171.8 million as of December 31, 2021. They anticipate topline data for the Saturn-2 Phase 3 trial in April 2022 and an NDA submission this year for TP-03.

  • Completed enrollment in the Saturn-2 Phase 3 trial for TP-03, with topline data expected in April 2022.
  • Reported positive pivotal Saturn-1 trial results, highlighting TP-03's potential as a standard of care for Demodex blepharitis patients.
  • Advanced TP-05 into the Callisto Phase 1b trial for Lyme disease prevention, with data expected in the second half of 2022.
  • Secured a $175 million non-dilutive credit facility and anticipate receiving $30 million in milestones in 2022 from the TP-03 out-license in Greater China.

Headline financials

Total Revenue

$338K

No prior period
EPS (adj)

-$0.72

Previous: -$1.85+61.1%
Capital Expenditures

$274K

Previous: -$50K+648.0%
Free Cash Flow

-$12.4M

Previous: -$9.96M-24.4%
Net Income

-$13.8M

Previous: -$26.8M+48.4%
Operating Income

-$14.4M

Previous: -$11.5M-25.9%
Gross Profit

-$7.68M

No prior period
Cash & Equivalents

$171M

Previous: $168M+1.9%
Total Assets

$179M

Previous: $172M+4.0%
Stock-Based Comp

$2.18M

Previous: $438K+397.5%

Revenue & EPS history

Tarsus · Revenue · Quarterly

$338K

Q4 2021
Beat estimate in 4 of 12 quarters(33%)
ActualEstimate

Forward guidance

Tarsus Pharmaceuticals anticipates several milestones in 2022, including topline data from the Saturn-2 trial and an NDA submission for TP-03. They also plan to initiate Phase 2 trials for TP-03 and TP-04, and expect Phase 1b data for TP-05.

Tailwinds

  • TP-03 Topline Pivotal Data (Saturn-2) for Demodex blepharitis anticipated in H1 2022
  • TP-03 Initiate Phase 2 (Ersa) for Meibomian Gland Disease anticipated in H1 2022
  • TP-03 NDA Submission for Demodex blepharitis anticipated in H2 2022
  • TP-04 Initiate Phase 2 (Galatea) for Rosacea anticipated in H2 2022
  • TP-05 Phase 1b Data (Callisto) for Lyme disease prevention anticipated in H2 2022

Headwinds

  • Tarsus has incurred significant losses and negative cash flows from operations since inception and anticipates that it will continue to incur significant expenses and losses for the foreseeable future
  • Tarsus may need to obtain additional funding to complete the development and any commercialization of its product candidates, if approved
  • Tarsus is heavily dependent on the success of its lead product candidate, TP-03 for the treatment of Demodex blepharitis
  • The COVID-19 pandemic may affect Tarsus’ ability to initiate and complete preclinical studies and clinical trials, disrupt regulatory activities, disrupt manufacturing and supply chain or have other adverse effects on Tarsus’ business and operations
  • Even if TP-03, TP-05, or any other product candidate that Tarsus develops receives marketing approval, Tarsus may not be successful in educating healthcare professionals and the market about the need for treatments specifically for Demodex blepharitis, Lyme disease, and/or other diseases or conditions targeted by Tarsus’ products

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+3.2%

Avg return

Earnings day

+4.2%

Avg return

5 days after

+17.8%

Avg return

30 days after

63%

15 / 24 earnings

Positive

+18.3%

Q2 2024

Best reaction

-10.5%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.4%-8.4%-9.0%
Q4 2025+9.6%+8.5%-3.4%
Q3 2025-4.7%+1.8%+14.4%
Q1 2025-6.1%-5.9%-14.6%
Q4 2024-9.3%-2.3%+11.2%
Q3 2024-1.9%-6.2%+10.4%
Q2 2024+18.3%+16.5%+34.8%
Q1 2024-10.5%+0.9%-15.3%
Q4 2023+14.2%+11.4%+9.6%
Q3 2023+5.6%+8.3%+4.5%
Q2 2023-2.5%-1.5%-7.0%
Q1 2023+7.1%+5.8%+25.9%
Q4 2022+0.4%-10.6%-15.8%
Q3 2022-0.1%-0.5%-14.2%
Q2 2022+5.4%+0.6%-8.3%
Q1 2022+7.2%+16.8%+25.4%
Q4 2021-4.9%-4.7%-1.1%
Q3 2021+0.4%-2.9%-13.8%
Q2 2021+6.2%+3.7%+13.3%
Q1 2021+2.9%+5.6%+38.3%
Q4 2020+16.4%+15.8%+8.6%
Q1 2020+7.5%+16.1%+111.4%
Q3 2020+7.5%+16.1%+111.4%
Q2 2020+7.5%+16.1%+111.4%
Q4 2019
Q3 2019
Q2 2018
Q1 2018

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