NASDAQ$TARS

Tarsus Pharmaceuticals Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Tarsus reported FY2025 XDEMVY net product sales of $451.4M, up more than 150% year over year.

Tarsus reported full-year 2025 XDEMVY net product sales of $451.4M, up more than 150% YoY, with peak sales potential guided above $2B. The company advanced Phase 2 trials for TP-04 in ocular rosacea and plans a Lyme disease prevention study for TP-05. Commercial momentum for XDEMVY remains the primary revenue driver.

  • FY2025 XDEMVY sales $451.4M (+150%+ YoY).
  • Peak sales potential guided above $2B.
  • Phase 2 TP-04 ocular rosacea trial initiated.
  • TP-05 Lyme prevention Phase 2 planned.

Headline financials

Total Revenue

$451M

Previous: $66.4M+579.7%
EPS (adj)

-$0.20

Previous: -$0.60+66.7%
Net Income

-$8.37M

Previous: -$23.1M+63.8%
Operating Income

-$7.98M

Previous: -$24.4M+67.3%
Gross Profit

$141M

Previous: $61.5M+128.9%

Revenue & EPS history

Tarsus · Revenue · Quarterly

$451M

Q4 2025+579.7%vs Q4 2024
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Forward guidance

Commercial focus on XDEMVY growth and lifecycle extensions via TP-04 and TP-05 programs.

Tailwinds

  • Rapid XDEMVY uptake supports blockbuster trajectory.
  • Pipeline expansion into adjacent eye-care indications.
  • Strong specialist community adoption.

Headwinds

  • Single-product concentration on XDEMVY.
  • Competitive demodex and eye-care therapies emerging.
  • Clinical trial risks for pipeline assets.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+3.2%

Avg return

Earnings day

+4.2%

Avg return

5 days after

+17.8%

Avg return

30 days after

63%

15 / 24 earnings

Positive

+18.3%

Q2 2024

Best reaction

-10.5%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.4%-8.4%-9.0%
Q4 2025+9.6%+8.5%-3.4%
Q3 2025-4.7%+1.8%+14.4%
Q1 2025-6.1%-5.9%-14.6%
Q4 2024-9.3%-2.3%+11.2%
Q3 2024-1.9%-6.2%+10.4%
Q2 2024+18.3%+16.5%+34.8%
Q1 2024-10.5%+0.9%-15.3%
Q4 2023+14.2%+11.4%+9.6%
Q3 2023+5.6%+8.3%+4.5%
Q2 2023-2.5%-1.5%-7.0%
Q1 2023+7.1%+5.8%+25.9%
Q4 2022+0.4%-10.6%-15.8%
Q3 2022-0.1%-0.5%-14.2%
Q2 2022+5.4%+0.6%-8.3%
Q1 2022+7.2%+16.8%+25.4%
Q4 2021-4.9%-4.7%-1.1%
Q3 2021+0.4%-2.9%-13.8%
Q2 2021+6.2%+3.7%+13.3%
Q1 2021+2.9%+5.6%+38.3%
Q4 2020+16.4%+15.8%+8.6%
Q1 2020+7.5%+16.1%+111.4%
Q3 2020+7.5%+16.1%+111.4%
Q2 2020+7.5%+16.1%+111.4%
Q4 2019
Q3 2019
Q2 2018
Q1 2018

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