NASDAQ$NBIX

Neurocrine Biosciences Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Neurocrine Biosciences reported financial results for Q3 2021, highlighted by INGREZZA's net product sales of $287 million and record total prescriptions.

Neurocrine Biosciences announced positive financial results for the third quarter of 2021, with INGREZZA's continued growth driving revenue. The company is expanding its commercial footprint and investing in its R&D pipeline, with several clinical data read-outs expected over the next two years.

  • Third quarter net product sales for INGREZZA were $287 million.
  • Record total prescriptions were achieved during the third quarter 2021, reflecting higher customer demand.
  • New prescriptions increased throughout the third quarter, reaching their highest levels since March 2020.
  • The company is expanding its commercial organization in 2022 to better meet the needs of healthcare professionals.

Headline financials

Total Revenue

$296M

Previous: $259M+14.5%
EPS (adj)

$0.64

Previous: $0.97-34.0%
GAAP R&D Expense

$92.7M

Previous: $69.1M+34.2%
GAAP SG&A Expense

$155M

Previous: $113M+37.4%
Capital Expenditures

-$14.5M

Previous: -$6.4M-126.6%
Free Cash Flow

$8M

Previous: -$64M+112.5%
Net Income

$22.5M

Previous: -$57.6M+139.1%
Operating Income

$44.5M

Previous: -$44.3M+200.5%
Gross Profit

$292M

Previous: $256M+14.1%
Cash & Equivalents

$311M

Previous: $425M-26.9%
Total Assets

$2.02B

Previous: $1.5B+34.3%
Stock-Based Comp

$37.1M

Previous: $26.7M+39.0%

Revenue & EPS history

Neurocrine Biosciences · Revenue · Quarterly

$296M

Q3 2021+14.5%vs Q3 2020
Beat estimate in 8 of 16 quarters(50%)
ActualEstimate

Revenue by segment

Neurocrine Biosciences · $294M total across 2 segments · Q3 2021

  • INGREZZA Net Product Sales
    $287M+13.0%
  • CRENESSITY Net Product Sales
    $7.2M

Forward guidance

Neurocrine Biosciences provides full-year 2021 expense guidance, with combined GAAP R&D and SG&A expenses expected to be between $895 million and $915 million, and combined Non-GAAP R&D and SG&A expenses expected to be between $760 million and $780 million.

Tailwinds

  • Registrational top-line data for Valbenazine in Chorea in Huntington Disease expected in December.
  • Mitsubishi Tanabe Pharma Corporation submitted Marketing Authorization with Ministry of Health and Welfare in Japan for Tardive Dyskinesia.
  • Initiating Registrational Study in Q4 for Dyskinesia Due to Cerebral Palsy.
  • Initiating Registrational Study in November for Adjunctive Treatment in Schizophrenia.
  • Enrolling Registrational Study for Crinecerfont in Congenital Adrenal Hyperplasia (Adult).

Headwinds

  • Risks associated with the commercialization of INGREZZA and ONGENTYS.
  • The impact of the evolving COVID-19 pandemic on our business and the business operations of our customers.
  • Risks and uncertainties associated with the scale and duration of the COVID-19 pandemic and resulting global, national, and local economic and financial disruptions.
  • Risk and uncertainties related to any COVID-19 quarantine, social distancing and other requirements put in place by governments, customers, or clinical trial sites, including the impact of such requirements on the ability of patients to have in-person visits with their health care provider.
  • Risks related to the development of our product candidates.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

-0.3%

Avg return

Earnings day

+1.1%

Avg return

5 days after

+1.6%

Avg return

30 days after

45%

29 / 65 earnings

Positive

+17.2%

Q3 2017

Best reaction

-18.5%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.8%+11.5%+21.3%
Q4 2025-10.4%-7.0%-5.6%
Q3 2025-6.3%-3.7%+3.2%
Q1 2025+8.3%+5.4%+13.5%
Q4 2024-18.5%-22.1%-24.9%
Q3 2024+3.5%+3.7%+9.1%
Q2 2024+8.2%+2.9%-10.2%
Q1 2024+1.7%+3.0%-1.5%
Q4 2023-6.0%-8.8%-2.6%
Q3 2023+4.1%+5.0%+8.8%
Q2 2023+2.2%-0.3%+6.9%
Q1 2023-7.4%-5.4%-10.8%
Q4 2022-5.6%-6.2%-11.1%
Q3 2022+6.0%+5.8%+9.7%
Q2 2022+10.6%+14.5%+9.5%
Q1 2022-3.9%-14.6%+7.7%
Q4 2021+8.7%+7.9%+12.2%
Q3 2021-9.3%-11.6%-23.4%
Q2 2021-2.8%-6.6%+0.4%
Q1 2021-2.3%-0.3%+3.2%
Q4 2020+3.1%+2.6%-17.3%
Q3 2020-9.1%-4.5%-4.5%
Q2 2020-0.2%-4.4%-3.7%
Q1 2020+7.0%+11.6%+13.8%
Q4 2019+2.0%+3.5%-5.4%
Q3 2019-1.2%+6.9%+14.4%
Q2 2019+9.7%+7.5%+11.3%
Q1 2019-6.7%+2.0%+1.4%
Q4 2018-4.6%-4.6%-12.9%
Q3 2018-8.0%-9.0%-25.5%
Q2 2018+14.7%+17.2%+23.3%
Q1 2018+3.3%+1.5%+17.1%
Q4 2017+3.9%+3.7%+11.6%
Q3 2017+17.2%+20.0%+18.5%
Q2 2017+10.2%+10.5%+17.4%
Q1 2017+3.4%+3.8%-15.3%
Q4 2016+0.7%+4.5%+7.2%
Q3 2016-10.0%-1.1%-3.1%
Q2 2016-0.7%-3.6%-2.0%
Q1 2016-0.1%
Q4 2015+6.9%
Q3 2015-4.5%
Q2 2015-3.7%
Q1 2015-4.4%
Q4 2014+5.7%
Q3 2014-4.9%
Q2 2014-2.3%
Q1 2014-3.5%
Q4 2013+1.3%
Q3 2013-6.3%
Q2 2013+0.5%
Q1 2013+2.3%
Q4 2012+6.5%
Q3 2012-1.7%
Q2 2012-9.6%
Q1 2011-3.2%
Q1 2012-3.2%
Q4 2011-8.0%
Q4 2009-8.0%
Q3 2010+13.7%
Q3 2011+13.7%
Q4 2010-6.5%
Q2 2010-6.5%
Q2 2011-6.5%
Q1 2010-1.5%

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