NASDAQ$NBIX

Neurocrine Biosciences Inc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Neurocrine Biosciences reported second quarter 2022 financial results and raised 2022 INGREZZA sales guidance.

Neurocrine Biosciences announced its financial results for the second quarter ended June 30, 2022, and raised net sales guidance for INGREZZA in 2022. INGREZZA's strong performance in the first half of the year drove the increased full-year net sales guidance.

  • Net product sales were $350 million with total prescriptions (TRx) of approximately 64,200.
  • Net product sales and TRx grew 32% and 31%, respectively, vs. second quarter of 2021.
  • Second quarter 2022 GAAP net loss and loss per share of $17 million and $0.18, respectively, compared with second quarter 2021 GAAP net income and diluted earnings per share of $42 million and $0.43, respectively.
  • Second quarter 2022 non-GAAP net income and diluted earnings per share of $82 million and $0.84, respectively, compared with $70 million and $0.72, respectively, for second quarter 2021.

Headline financials

Total Revenue

$378M

Previous: $289M+30.9%
EPS (adj)

$0.84

Previous: $0.63+33.3%
GAAP R&D Expense

$136M

Previous: $74.8M+81.7%
GAAP SG&A Expense

$183M

Previous: $143M+27.7%
Capital Expenditures

-$16.4M

Previous: -$8.8M-86.4%
Free Cash Flow

-$33.3M

Previous: $33.5M-199.4%
Net Income

-$16.9M

Previous: $42.3M-140.0%
Operating Income

$54.7M

Previous: $62.8M-12.9%
Gross Profit

$373M

Previous: $286M+30.7%
Cash & Equivalents

$163M

Previous: $368M-55.6%
Total Assets

$2.01B

Previous: $1.96B+2.5%
Stock-Based Comp

$49.5M

Previous: $28.6M+73.1%

Revenue & EPS history

Neurocrine Biosciences · Revenue · Quarterly

$378M

Q2 2022+30.9%vs Q2 2021
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Neurocrine Biosciences · $350M total across 1 segment · Q2 2022

  • INGREZZA Net Product Sales
    $350M+32.1%

Forward guidance

Neurocrine Biosciences updated 2022 INGREZZA sales and operating expense guidance.

Tailwinds

  • INGREZZA Net Product Sales: $1,350 - $1,400 million
  • GAAP R&D expense: $415 - $450 million
  • Non-GAAP R&D expense: $360 - $395 million
  • GAAP SG&A expense: $720 - $735 million
  • Non-GAAP SG&A expense: $605 - $620 million

Headwinds

  • If new COVID-19 related disruptions emerge, the Company’s ability to meet these expectations could be negatively impacted.
  • GAAP R&D guidance includes (i) amounts for milestones that are probable of achievement or have been achieved and (ii) amounts for in-process research and development once significant collaboration and licensing arrangements have been completed.
  • GAAP R&D guidance includes approximately $40 million of milestone expenses in connection with collaborations.
  • Non-GAAP guidance adjusted to exclude estimated non-cash stock-based compensation expense of $60 million in R&D and $110 million in SG&A.
  • Based upon available Federal net operating losses and tax credits, the Company expects to begin making cash payments for Federal income tax beginning in the fourth quarter of 2022.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

-0.3%

Avg return

Earnings day

+1.1%

Avg return

5 days after

+1.6%

Avg return

30 days after

45%

29 / 65 earnings

Positive

+17.2%

Q3 2017

Best reaction

-18.5%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.8%+11.5%+21.3%
Q4 2025-10.4%-7.0%-5.6%
Q3 2025-6.3%-3.7%+3.2%
Q1 2025+8.3%+5.4%+13.5%
Q4 2024-18.5%-22.1%-24.9%
Q3 2024+3.5%+3.7%+9.1%
Q2 2024+8.2%+2.9%-10.2%
Q1 2024+1.7%+3.0%-1.5%
Q4 2023-6.0%-8.8%-2.6%
Q3 2023+4.1%+5.0%+8.8%
Q2 2023+2.2%-0.3%+6.9%
Q1 2023-7.4%-5.4%-10.8%
Q4 2022-5.6%-6.2%-11.1%
Q3 2022+6.0%+5.8%+9.7%
Q2 2022+10.6%+14.5%+9.5%
Q1 2022-3.9%-14.6%+7.7%
Q4 2021+8.7%+7.9%+12.2%
Q3 2021-9.3%-11.6%-23.4%
Q2 2021-2.8%-6.6%+0.4%
Q1 2021-2.3%-0.3%+3.2%
Q4 2020+3.1%+2.6%-17.3%
Q3 2020-9.1%-4.5%-4.5%
Q2 2020-0.2%-4.4%-3.7%
Q1 2020+7.0%+11.6%+13.8%
Q4 2019+2.0%+3.5%-5.4%
Q3 2019-1.2%+6.9%+14.4%
Q2 2019+9.7%+7.5%+11.3%
Q1 2019-6.7%+2.0%+1.4%
Q4 2018-4.6%-4.6%-12.9%
Q3 2018-8.0%-9.0%-25.5%
Q2 2018+14.7%+17.2%+23.3%
Q1 2018+3.3%+1.5%+17.1%
Q4 2017+3.9%+3.7%+11.6%
Q3 2017+17.2%+20.0%+18.5%
Q2 2017+10.2%+10.5%+17.4%
Q1 2017+3.4%+3.8%-15.3%
Q4 2016+0.7%+4.5%+7.2%
Q3 2016-10.0%-1.1%-3.1%
Q2 2016-0.7%-3.6%-2.0%
Q1 2016-0.1%
Q4 2015+6.9%
Q3 2015-4.5%
Q2 2015-3.7%
Q1 2015-4.4%
Q4 2014+5.7%
Q3 2014-4.9%
Q2 2014-2.3%
Q1 2014-3.5%
Q4 2013+1.3%
Q3 2013-6.3%
Q2 2013+0.5%
Q1 2013+2.3%
Q4 2012+6.5%
Q3 2012-1.7%
Q2 2012-9.6%
Q1 2011-3.2%
Q1 2012-3.2%
Q4 2011-8.0%
Q4 2009-8.0%
Q3 2010+13.7%
Q3 2011+13.7%
Q4 2010-6.5%
Q2 2010-6.5%
Q2 2011-6.5%
Q1 2010-1.5%

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