NASDAQ$NBIX

Neurocrine Biosciences Inc · Q2 2021 earnings

Q2 2021 earnings · · Investor relations

Briefing

Reported sustained growth for INGREZZA and advancements in the R&D pipeline.

Neurocrine Biosciences reported second quarter 2021 financial results, highlighting sustained growth for INGREZZA with net product sales of $265 million and approximately 48,900 total prescriptions. The company is also advancing its R&D pipeline with 9 mid-to-late-stage clinical trials planned for this year.

  • INGREZZA net product sales reached $265 million in Q2 2021 with approximately 48,900 total prescriptions.
  • Record total prescriptions were achieved during the second quarter 2021, reflecting increased commercial activities.
  • New prescriptions increased throughout the second quarter, reaching their highest levels since March 2020 despite continued significant use of telemedicine within psychiatry.
  • Second quarter refill rates per patient returned to historical normal range versus seasonally low first quarter levels.

Headline financials

Total Revenue

$289M

Previous: $302M-4.5%
EPS (adj)

$0.63

Previous: $1.42-55.6%
GAAP R&D Expense

$74.8M

No prior period
GAAP SG&A Expense

$143M

No prior period
Capital Expenditures

-$8.8M

Previous: -$6M-46.7%
Free Cash Flow

$33.5M

Previous: $73.6M-54.5%
Net Income

$42.3M

Previous: $79.6M-46.9%
Operating Income

$62.8M

Previous: $76.6M-18.0%
Gross Profit

$286M

Previous: $300M-4.7%
Cash & Equivalents

$368M

Previous: $415M-11.3%
Total Assets

$1.96B

Previous: $1.52B+29.1%
Stock-Based Comp

$28.6M

Previous: $29.5M-3.1%

Revenue & EPS history

Neurocrine Biosciences · Revenue · Quarterly

$289M

Q2 2021-4.5%vs Q2 2020
Beat estimate in 7 of 16 quarters(44%)
ActualEstimate

Revenue by segment

Neurocrine Biosciences · $265M total across 1 segment · Q2 2021

  • INGREZZA Net Product Sales
    $265M-1.0%

Forward guidance

Neurocrine Biosciences reaffirms its full-year 2021 expense guidance, with combined GAAP R&D and SG&A expenses expected to be in the range of $855 million to $905 million, and combined Non-GAAP R&D and SG&A expenses expected to be in the range of $720 million to $770 million.

Tailwinds

  • Continued success of INGREZZA
  • Advancement of clinical programs
  • Potential benefits from collaborative partnerships
  • Ability to adapt business to the evolving COVID-19 pandemic
  • Mitigation of COVID-19 impact on the business

Headwinds

  • Future financial and operating performance
  • Risks associated with commercialization of INGREZZA and ONGENTYS
  • Impact of the evolving COVID-19 pandemic
  • Dependence on third parties for development and manufacturing activities
  • Potential adverse decisions by the FDA or other regulatory authorities

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2021

Historical avgQ2 2021

-0.3%

Avg return

Earnings day

+1.1%

Avg return

5 days after

+1.6%

Avg return

30 days after

45%

29 / 65 earnings

Positive

+17.2%

Q3 2017

Best reaction

-18.5%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.8%+11.5%+21.3%
Q4 2025-10.4%-7.0%-5.6%
Q3 2025-6.3%-3.7%+3.2%
Q1 2025+8.3%+5.4%+13.5%
Q4 2024-18.5%-22.1%-24.9%
Q3 2024+3.5%+3.7%+9.1%
Q2 2024+8.2%+2.9%-10.2%
Q1 2024+1.7%+3.0%-1.5%
Q4 2023-6.0%-8.8%-2.6%
Q3 2023+4.1%+5.0%+8.8%
Q2 2023+2.2%-0.3%+6.9%
Q1 2023-7.4%-5.4%-10.8%
Q4 2022-5.6%-6.2%-11.1%
Q3 2022+6.0%+5.8%+9.7%
Q2 2022+10.6%+14.5%+9.5%
Q1 2022-3.9%-14.6%+7.7%
Q4 2021+8.7%+7.9%+12.2%
Q3 2021-9.3%-11.6%-23.4%
Q2 2021-2.8%-6.6%+0.4%
Q1 2021-2.3%-0.3%+3.2%
Q4 2020+3.1%+2.6%-17.3%
Q3 2020-9.1%-4.5%-4.5%
Q2 2020-0.2%-4.4%-3.7%
Q1 2020+7.0%+11.6%+13.8%
Q4 2019+2.0%+3.5%-5.4%
Q3 2019-1.2%+6.9%+14.4%
Q2 2019+9.7%+7.5%+11.3%
Q1 2019-6.7%+2.0%+1.4%
Q4 2018-4.6%-4.6%-12.9%
Q3 2018-8.0%-9.0%-25.5%
Q2 2018+14.7%+17.2%+23.3%
Q1 2018+3.3%+1.5%+17.1%
Q4 2017+3.9%+3.7%+11.6%
Q3 2017+17.2%+20.0%+18.5%
Q2 2017+10.2%+10.5%+17.4%
Q1 2017+3.4%+3.8%-15.3%
Q4 2016+0.7%+4.5%+7.2%
Q3 2016-10.0%-1.1%-3.1%
Q2 2016-0.7%-3.6%-2.0%
Q1 2016-0.1%
Q4 2015+6.9%
Q3 2015-4.5%
Q2 2015-3.7%
Q1 2015-4.4%
Q4 2014+5.7%
Q3 2014-4.9%
Q2 2014-2.3%
Q1 2014-3.5%
Q4 2013+1.3%
Q3 2013-6.3%
Q2 2013+0.5%
Q1 2013+2.3%
Q4 2012+6.5%
Q3 2012-1.7%
Q2 2012-9.6%
Q1 2011-3.2%
Q1 2012-3.2%
Q4 2011-8.0%
Q4 2009-8.0%
Q3 2010+13.7%
Q3 2011+13.7%
Q4 2010-6.5%
Q2 2010-6.5%
Q2 2011-6.5%
Q1 2010-1.5%

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