NASDAQ$SAGE

Sage Therapeutics Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Sage Therapeutics reported financial results for the third quarter of 2021 and highlighted pipeline and business progress.

Sage Therapeutics reported a net revenue of $1.4 million from sales of ZULRESSO in Q3 2021, compared to $1.6 million in the same period of 2020. The company's cash, cash equivalents, and marketable securities totaled $1.8 billion as of September 30, 2021. They are advancing their portfolio of clinical programs, notably zuranolone for MDD and PPD, and planning to file an NDA for zuranolone in the second half of 2022.

  • Sage and Biogen plan to submit an NDA to the FDA for zuranolone in the second half of 2022 for MDD, with an additional filing for PPD anticipated in the first half of 2023.
  • The primary endpoint for the CORAL Study (HAMD-17 change from baseline) will be measured at Day 3.
  • Sage plans to initiate an open-label study designed to demonstrate the safe-use administration of ZULRESSO in a patient’s home in the treatment of PPD.
  • Sage and Biogen advanced plans to initiate a Phase 2 dose-ranging study for SAGE-324 in ET in late 2021.

Headline financials

Total Revenue

$1.44M

Previous: $1.64M-12.1%
EPS (adj)

-$2.21

Previous: -$2.03-8.9%
Net Income

-$130M

Previous: -$106M-23.1%
Operating Income

-$131M

Previous: -$107M-22.2%
Gross Profit

$1.31M

Previous: $1.49M-12.1%
Cash & Equivalents

$1.8B

Previous: $671M+168.3%
Total Assets

$1.93B

Previous: $739M+160.9%
Stock-Based Comp

$34.3M

Previous: $20.1M+70.8%

Revenue & EPS history

Sage · Revenue · Quarterly

$1.44M

Q3 2021-12.1%vs Q3 2020
Beat estimate in 3 of 15 quarters(20%)
ActualEstimate

Revenue by segment

Sage · $1.64M total across 1 segment · Q4 2021

  • ZULRESSO Net Revenue
    $1.64M

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

-2.8%

Avg return

Earnings day

-5.3%

Avg return

5 days after

-6.4%

Avg return

30 days after

43%

19 / 44 earnings

Positive

+12.4%

Q4 2021

Best reaction

-47.6%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025
Q2 2025
Q1 2025-4.1%-5.7%-15.0%
Q4 2024-0.4%-0.8%+7.2%
Q3 2024-24.6%-29.1%-35.2%
Q2 2024-9.6%-17.2%-22.1%
Q1 2024-2.2%-0.6%-19.4%
Q4 2023+10.4%+1.3%-13.2%
Q3 2023-10.2%-17.1%+1.3%
Q2 2023-47.6%-39.7%-42.8%
Q1 2023-2.4%+0.9%+1.9%
Q4 2022+0.9%-5.2%-5.2%
Q3 2022-5.0%+5.0%+16.5%
Q2 2022+4.6%+21.6%+12.8%
Q1 2022+4.9%-12.2%+12.6%
Q4 2021+12.4%+12.3%-1.0%
Q3 2021+11.2%+6.4%-9.7%
Q2 2021-4.0%-5.1%+9.0%
Q1 2021-10.3%
Q4 2020+4.0%
Q3 2020-0.6%
Q2 2020+1.3%
Q1 2020-4.1%
Q4 2019-26.2%
Q3 2019-0.2%
Q2 2019+7.4%
Q1 2019+0.3%
Q4 2018-8.2%
Q3 2018+3.0%
Q2 2018-0.7%
Q1 2018+1.2%
Q4 2017+0.2%
Q3 2017+11.7%
Q2 2017+7.7%
Q1 2017-2.7%
Q4 2016+0.6%
Q3 2016+0.5%
Q2 2016-13.3%
Q1 2016-3.8%
Q4 2015-4.8%
Q3 2015-4.6%
Q2 2015-6.5%
Q1 2015+2.0%
Q4 2014+2.1%
Q3 2014-5.2%
Q2 2014-7.8%
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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