NASDAQ$SAGE

Sage Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close · Investor relations

Briefing

Sage Therapeutics reported Q2 2025 total revenues of $31.7M with a net loss of $49.7M and diluted EPS of $(0.79).

Total revenues were $31.7 million, primarily collaboration revenue related to ZURZUVAE with Biogen. Net loss was $49.7 million, or $0.79 per diluted share, as the company prioritized PPD commercialization and pipeline prioritization after discontinuing ZULRESSO.

  • Q2 total revenues $31.7M.
  • Net loss $49.7M; diluted EPS $(0.79).
  • ZURZUVAE PPD launch with Biogen is strategic focus.
  • R&D spend on SAGE-319 and platform candidates.

Headline financials

Total Revenue

$31.7M

Previous: $8.65M+265.8%
EPS (adj)

-$0.79

Previous: -$1.70+53.5%
Net Income

-$49.7M

Previous: -$103M+51.7%
Operating Income

$54K

Previous: -$111M+100.0%

Revenue & EPS history

Sage · Revenue · Quarterly

$31.7M

Q2 2025+265.8%vs Q2 2024
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Revenue by segment

Sage · $1.64M total across 1 segment · Q4 2021

  • ZULRESSO Net Revenue
    $1.64M

Forward guidance

Healthcare outlook emphasizes reimbursement, pipeline milestones, and path to profitability.

Tailwinds

  • Product launches and partnership economics.
  • Cost discipline and cash runway.

Headwinds

  • Clinical, regulatory, and pricing risk.
  • Operating losses until scale is reached.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports

Historical avg

-2.8%

Avg return

Earnings day

-5.3%

Avg return

5 days after

-6.4%

Avg return

30 days after

43%

19 / 44 earnings

Positive

+12.4%

Q4 2021

Best reaction

-47.6%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025
Q2 2025
Q1 2025-4.1%-5.7%-15.0%
Q4 2024-0.4%-0.8%+7.2%
Q3 2024-24.6%-29.1%-35.2%
Q2 2024-9.6%-17.2%-22.1%
Q1 2024-2.2%-0.6%-19.4%
Q4 2023+10.4%+1.3%-13.2%
Q3 2023-10.2%-17.1%+1.3%
Q2 2023-47.6%-39.7%-42.8%
Q1 2023-2.4%+0.9%+1.9%
Q4 2022+0.9%-5.2%-5.2%
Q3 2022-5.0%+5.0%+16.5%
Q2 2022+4.6%+21.6%+12.8%
Q1 2022+4.9%-12.2%+12.6%
Q4 2021+12.4%+12.3%-1.0%
Q3 2021+11.2%+6.4%-9.7%
Q2 2021-4.0%-5.1%+9.0%
Q1 2021-10.3%
Q4 2020+4.0%
Q3 2020-0.6%
Q2 2020+1.3%
Q1 2020-4.1%
Q4 2019-26.2%
Q3 2019-0.2%
Q2 2019+7.4%
Q1 2019+0.3%
Q4 2018-8.2%
Q3 2018+3.0%
Q2 2018-0.7%
Q1 2018+1.2%
Q4 2017+0.2%
Q3 2017+11.7%
Q2 2017+7.7%
Q1 2017-2.7%
Q4 2016+0.6%
Q3 2016+0.5%
Q2 2016-13.3%
Q1 2016-3.8%
Q4 2015-4.8%
Q3 2015-4.6%
Q2 2015-6.5%
Q1 2015+2.0%
Q4 2014+2.1%
Q3 2014-5.2%
Q2 2014-7.8%
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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