NASDAQ$PTGX

Protagonist Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter and full year ended December 31, 2021 and provided a corporate update.

Protagonist Therapeutics reported its fourth quarter financial results and provided a corporate update, highlighting the advancement of rusfertide into a Phase 3 registrational study, completion of enrollment for PN-943 Phase 2 study, and progression of PN-235 into a Phase 2b study by Janssen.

  • Rusfertide is moving into a Phase 3 registrational study for polycythemia vera.
  • Enrollment is complete for PN-943 Phase 2 proof-of-concept study in ulcerative colitis.
  • Janssen is progressing PN-235 into a Phase 2b study in plaque psoriasis.
  • The company anticipates topline data readout from the Phase 2 IDEAL study of PN-943 in ulcerative colitis in the second quarter of this year.

Headline financials

Total Revenue

$8.62M

Previous: $5.65M+52.5%
EPS (adj)

-$0.77

Previous: -$0.48-60.4%
Capital Expenditures

$196K

Previous: $125K+56.8%
Free Cash Flow

-$27.1M

Previous: -$19M-42.9%
Net Income

-$36.9M

Previous: -$18.9M-95.4%
Operating Income

-$37M

Previous: -$18.8M-96.6%
Gross Profit

$7.8M

Previous: $5.65M+38.0%
Cash & Equivalents

$124M

Previous: $117M+5.4%
Total Assets

$348M

Previous: $324M+7.2%
Stock-Based Comp

$5.02M

Previous: $1.97M+155.4%

Revenue & EPS history

Protagonist · Revenue · Quarterly

$8.62M

Q4 2021+52.5%vs Q4 2020
Beat estimate in 10 of 15 quarters(67%)
ActualEstimate

Forward guidance

Protagonist Therapeutics plans to continue to demonstrate strength of execution across all current and emerging assets in its pipeline, thereby maximizing the opportunities ahead for substantial value creation this year.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+3.2%

Avg return

Earnings day

+5.4%

Avg return

5 days after

+8.3%

Avg return

30 days after

51%

20 / 39 earnings

Positive

+75.1%

Q1 2020

Best reaction

-21.2%

Q1 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.2%+3.3%
Q4 2025-0.3%+7.8%+13.3%
Q3 2025-0.2%+6.4%+12.4%
Q1 2025+2.4%+3.2%+22.9%
Q4 2024-7.1%-6.2%+35.6%
Q3 2024-2.9%-9.3%-11.6%
Q2 2024+0.0%+8.2%+17.4%
Q1 2024+4.0%+8.3%+30.5%
Q4 2023+3.0%+8.9%-2.0%
Q3 2023+10.2%+9.0%+22.8%
Q2 2023+3.3%-2.0%+5.2%
Q1 2023+1.5%+3.3%+15.3%
Q4 2022-8.4%-9.9%-25.9%
Q3 2022-0.5%+9.4%+0.4%
Q2 2022+2.2%-1.6%-21.1%
Q1 2022-0.3%-10.3%-6.4%
Q4 2021+7.2%-0.7%-2.3%
Q3 2021+5.0%+7.4%+0.1%
Q2 2021-2.2%-0.4%-0.8%
Q1 2021-0.4%-0.1%+19.3%
Q4 2020+3.5%+2.8%-11.4%
Q3 2020+14.2%+6.6%+11.0%
Q2 2020+8.3%+2.3%+23.8%
Q1 2020+75.1%+97.4%+98.0%
Q4 2019-4.8%+5.1%-7.6%
Q3 2019-19.3%-14.2%-37.5%
Q2 2019+0.8%-2.9%+60.6%
Q1 2019+20.8%+16.3%+31.4%
Q4 2018+0.1%+22.3%+22.2%
Q3 2018+14.1%+22.3%-14.6%
Q2 2018-1.8%-6.4%-18.1%
Q1 2018-21.2%-22.4%-13.5%
Q4 2017-2.0%+1.4%-57.5%
Q3 2017+8.9%+16.2%+25.2%
Q2 2017-7.7%-4.4%+33.6%
Q1 2017+10.5%+14.3%+21.1%
Q4 2016-0.6%+0.4%-16.8%
Q3 2016-1.6%+3.4%-16.5%
Q2 2016+9.4%+19.1%+63.8%
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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