NASDAQ$PTGX

Protagonist Therapeutics Inc · Q3 2024 earnings

Q3 2024 earnings · · Investor relations

Briefing

Protagonist reported financial results for the third quarter ended September 30, 2024.

Protagonist Therapeutics reported its third quarter 2024 financial results, highlighting upcoming milestones for its drug candidates and a strong cash position to support development programs.

  • Top line results are expected in Q4 2024 for JNJ-2113 Phase 3 ICONIC-LEAD and Phase 3 ICONIC-TOTAL clinical trials in patients with moderate to severe psoriasis.
  • Top line results are expected in Q1 2025 for JNJ-2113 Phase 2b ANTHEM clinical trial in moderate to severe ulcerative colitis.
  • Top line results are expected in Q1 2025 for rusfertide Phase 3 VERIFY clinical trial in polycythemia vera.
  • The company anticipates cash runway through end of 2027, with cash, cash equivalents, and marketable securities of $583.3 million as of September 30, 2024.

Headline financials

Total Revenue

$4.68M

Previous: $0.00
EPS

-$0.54

Previous: -$0.58+6.9%
Capital Expenditures

-$1.05M

Previous: -$590K-77.1%
Free Cash Flow

-$34.3M

Previous: -$34.7M+1.3%
Net Income

-$33.2M

Previous: -$34.1M+2.6%
Operating Income

-$41.5M

Previous: -$38.3M-8.2%
Gross Profit

$34K

Previous: $0.00
R&D Expense

$36M

Previous: $30.7M+17.3%
Stock-Based Comp

$10.2M

Previous: $6.77M+50.3%

Revenue & EPS history

Protagonist · Revenue · Quarterly

$4.68M

Q3 2024
Beat estimate in 6 of 13 quarters(46%)
ActualEstimate

Forward guidance

Protagonist is focused on advancing its clinical trials and expects multiple data readouts in the near term, while also progressing its discovery programs.

Tailwinds

  • Top line results for JNJ-2113 Phase 3 trials in psoriasis expected in Q4 2024.
  • Top line results for JNJ-2113 Phase 2b trial in ulcerative colitis expected in Q1 2025.
  • Top line results for rusfertide Phase 3 trial in polycythemia vera expected in Q1 2025.
  • Development candidate nomination for oral IL-17 peptide antagonist expected in Q4 2024.
  • Strong cash position provides runway through end of 2027.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2024

Historical avgQ3 2024

+3.2%

Avg return

Earnings day

+5.4%

Avg return

5 days after

+8.3%

Avg return

30 days after

51%

20 / 39 earnings

Positive

+75.1%

Q1 2020

Best reaction

-21.2%

Q1 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.2%+3.3%
Q4 2025-0.3%+7.8%+13.3%
Q3 2025-0.2%+6.4%+12.4%
Q1 2025+2.4%+3.2%+22.9%
Q4 2024-7.1%-6.2%+35.6%
Q3 2024-2.9%-9.3%-11.6%
Q2 2024+0.0%+8.2%+17.4%
Q1 2024+4.0%+8.3%+30.5%
Q4 2023+3.0%+8.9%-2.0%
Q3 2023+10.2%+9.0%+22.8%
Q2 2023+3.3%-2.0%+5.2%
Q1 2023+1.5%+3.3%+15.3%
Q4 2022-8.4%-9.9%-25.9%
Q3 2022-0.5%+9.4%+0.4%
Q2 2022+2.2%-1.6%-21.1%
Q1 2022-0.3%-10.3%-6.4%
Q4 2021+7.2%-0.7%-2.3%
Q3 2021+5.0%+7.4%+0.1%
Q2 2021-2.2%-0.4%-0.8%
Q1 2021-0.4%-0.1%+19.3%
Q4 2020+3.5%+2.8%-11.4%
Q3 2020+14.2%+6.6%+11.0%
Q2 2020+8.3%+2.3%+23.8%
Q1 2020+75.1%+97.4%+98.0%
Q4 2019-4.8%+5.1%-7.6%
Q3 2019-19.3%-14.2%-37.5%
Q2 2019+0.8%-2.9%+60.6%
Q1 2019+20.8%+16.3%+31.4%
Q4 2018+0.1%+22.3%+22.2%
Q3 2018+14.1%+22.3%-14.6%
Q2 2018-1.8%-6.4%-18.1%
Q1 2018-21.2%-22.4%-13.5%
Q4 2017-2.0%+1.4%-57.5%
Q3 2017+8.9%+16.2%+25.2%
Q2 2017-7.7%-4.4%+33.6%
Q1 2017+10.5%+14.3%+21.1%
Q4 2016-0.6%+0.4%-16.8%
Q3 2016-1.6%+3.4%-16.5%
Q2 2016+9.4%+19.1%+63.8%
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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