NASDAQ$PTGX

Protagonist Therapeutics Inc · Q2 2024 earnings

Q2 2024 earnings · · Investor relations

Briefing

Reported financial results for the second quarter ended June 30, 2024, and provided a corporate update.

Protagonist Therapeutics reported second quarter 2024 financial results, highlighting advancements in rusfertide and JNJ-2113 clinical development, and the expansion of their discovery platform for oral peptides-based programs. The company also noted its addition to the S&P SmallCap 600® index.

  • Rusfertide's Phase 2 REVIVE trial data reaffirmed durable positive response in polycythemia vera.
  • Phase 3 VERIFY 32-week primary endpoint readout for rusfertide is expected in Q1 2025.
  • Rapid enrollment is ongoing in five Phase 3 trials of JNJ-2113 in psoriasis and a Phase 2b study in ulcerative colitis.
  • Primary endpoint portion of ICONIC-LEAD, ICONIC-TOTAL, and ANTHEM studies are expected to be completed this year.

Headline financials

Total Revenue

$4.17M

Previous: $0.00
EPS

-$0.50

Previous: -$0.68+26.5%
Capital Expenditures

-$270K

Previous: -$186K-45.2%
Free Cash Flow

-$30.9M

Previous: -$38.6M+20.1%
Net Income

-$30.6M

Previous: -$38.5M+20.4%
Operating Income

-$38.8M

Previous: -$42.4M+8.4%
Gross Profit

$34K

No prior period
R&D Expense

$33.5M

No prior period
Stock-Based Comp

$8.94M

Previous: $8.34M+7.2%

Revenue & EPS history

Protagonist · Revenue · Quarterly

$4.17M

Q2 2024
Beat estimate in 6 of 13 quarters(46%)
ActualEstimate

Forward guidance

Protagonist anticipates multiple new development candidates in various indications over the next 12 months and expects completion of primary endpoint portions for several Phase 3 trials of JNJ-2113 and the Phase 2b study in ulcerative colitis this year.

Tailwinds

  • Potential for multiple new development candidates in various indications.
  • Strong differentiation offered by oral peptides versus existing options.
  • Rapid pace of enrollment in ongoing Phase 3 trials of JNJ-2113.
  • Expected completion of primary endpoint portions for ICONIC-LEAD, ICONIC-TOTAL, and ANTHEM studies this year.
  • Potential and differentiation of JNJ-2113 as the first and only targeted oral IL-23 receptor antagonist.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2024

Historical avgQ2 2024

+3.2%

Avg return

Earnings day

+5.4%

Avg return

5 days after

+8.3%

Avg return

30 days after

51%

20 / 39 earnings

Positive

+75.1%

Q1 2020

Best reaction

-21.2%

Q1 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.2%+3.3%
Q4 2025-0.3%+7.8%+13.3%
Q3 2025-0.2%+6.4%+12.4%
Q1 2025+2.4%+3.2%+22.9%
Q4 2024-7.1%-6.2%+35.6%
Q3 2024-2.9%-9.3%-11.6%
Q2 2024+0.0%+8.2%+17.4%
Q1 2024+4.0%+8.3%+30.5%
Q4 2023+3.0%+8.9%-2.0%
Q3 2023+10.2%+9.0%+22.8%
Q2 2023+3.3%-2.0%+5.2%
Q1 2023+1.5%+3.3%+15.3%
Q4 2022-8.4%-9.9%-25.9%
Q3 2022-0.5%+9.4%+0.4%
Q2 2022+2.2%-1.6%-21.1%
Q1 2022-0.3%-10.3%-6.4%
Q4 2021+7.2%-0.7%-2.3%
Q3 2021+5.0%+7.4%+0.1%
Q2 2021-2.2%-0.4%-0.8%
Q1 2021-0.4%-0.1%+19.3%
Q4 2020+3.5%+2.8%-11.4%
Q3 2020+14.2%+6.6%+11.0%
Q2 2020+8.3%+2.3%+23.8%
Q1 2020+75.1%+97.4%+98.0%
Q4 2019-4.8%+5.1%-7.6%
Q3 2019-19.3%-14.2%-37.5%
Q2 2019+0.8%-2.9%+60.6%
Q1 2019+20.8%+16.3%+31.4%
Q4 2018+0.1%+22.3%+22.2%
Q3 2018+14.1%+22.3%-14.6%
Q2 2018-1.8%-6.4%-18.1%
Q1 2018-21.2%-22.4%-13.5%
Q4 2017-2.0%+1.4%-57.5%
Q3 2017+8.9%+16.2%+25.2%
Q2 2017-7.7%-4.4%+33.6%
Q1 2017+10.5%+14.3%+21.1%
Q4 2016-0.6%+0.4%-16.8%
Q3 2016-1.6%+3.4%-16.5%
Q2 2016+9.4%+19.1%+63.8%
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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