NASDAQ$PTGX

Protagonist Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results for the first quarter of 2022 and provided a corporate update.

Protagonist Therapeutics reaffirmed rusfertide as the primary focus, presented topline results from the Phase 2 IDEAL study of PN-943 in ulcerative colitis, and received a $25 million milestone payment from Janssen.

  • Initiated Phase 3 VERIFY study of rusfertide in polycythemia vera.
  • Presented topline results from the Phase 2 IDEAL study of PN-943 in ulcerative colitis with consistent treatment effects at the lower 150 mg BID dose across key endpoints.
  • Engaged PJT Partners to lead external partnering efforts for PN-943.
  • Received a milestone payment of $25 million from Janssen upon dosing of the third patient in the Phase 2B FRONTIER-1 study of PN-235 in psoriasis.

Headline financials

Total Revenue

$25.7M

Previous: $6.19M+315.6%
EPS (adj)

-$0.43

Previous: -$0.54+20.4%
Capital Expenditures

-$273K

Previous: $140K-295.0%
Free Cash Flow

-$21.2M

Previous: -$28.9M+26.6%
Net Income

-$20.9M

Previous: -$24M+12.8%
Operating Income

-$21.1M

Previous: -$24M+12.1%
Gross Profit

$24.9M

Previous: $6.19M+302.1%
Cash & Equivalents

$98.5M

Previous: $83M+18.6%
Total Assets

$348M

Previous: $298M+16.8%
Stock-Based Comp

$5.94M

Previous: $2.66M+123.1%

Revenue & EPS history

Protagonist · Revenue · Quarterly

$25.7M

Q1 2022+315.6%vs Q1 2021
Beat estimate in 9 of 14 quarters(64%)
ActualEstimate

Forward guidance

Protagonist expects activities related to PN-943 to have a minimal impact on cash resources and retains cash runway guidance through the end of 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+3.2%

Avg return

Earnings day

+5.4%

Avg return

5 days after

+8.3%

Avg return

30 days after

51%

20 / 39 earnings

Positive

+75.1%

Q1 2020

Best reaction

-21.2%

Q1 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.2%+3.3%
Q4 2025-0.3%+7.8%+13.3%
Q3 2025-0.2%+6.4%+12.4%
Q1 2025+2.4%+3.2%+22.9%
Q4 2024-7.1%-6.2%+35.6%
Q3 2024-2.9%-9.3%-11.6%
Q2 2024+0.0%+8.2%+17.4%
Q1 2024+4.0%+8.3%+30.5%
Q4 2023+3.0%+8.9%-2.0%
Q3 2023+10.2%+9.0%+22.8%
Q2 2023+3.3%-2.0%+5.2%
Q1 2023+1.5%+3.3%+15.3%
Q4 2022-8.4%-9.9%-25.9%
Q3 2022-0.5%+9.4%+0.4%
Q2 2022+2.2%-1.6%-21.1%
Q1 2022-0.3%-10.3%-6.4%
Q4 2021+7.2%-0.7%-2.3%
Q3 2021+5.0%+7.4%+0.1%
Q2 2021-2.2%-0.4%-0.8%
Q1 2021-0.4%-0.1%+19.3%
Q4 2020+3.5%+2.8%-11.4%
Q3 2020+14.2%+6.6%+11.0%
Q2 2020+8.3%+2.3%+23.8%
Q1 2020+75.1%+97.4%+98.0%
Q4 2019-4.8%+5.1%-7.6%
Q3 2019-19.3%-14.2%-37.5%
Q2 2019+0.8%-2.9%+60.6%
Q1 2019+20.8%+16.3%+31.4%
Q4 2018+0.1%+22.3%+22.2%
Q3 2018+14.1%+22.3%-14.6%
Q2 2018-1.8%-6.4%-18.1%
Q1 2018-21.2%-22.4%-13.5%
Q4 2017-2.0%+1.4%-57.5%
Q3 2017+8.9%+16.2%+25.2%
Q2 2017-7.7%-4.4%+33.6%
Q1 2017+10.5%+14.3%+21.1%
Q4 2016-0.6%+0.4%-16.8%
Q3 2016-1.6%+3.4%-16.5%
Q2 2016+9.4%+19.1%+63.8%
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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