NASDAQ$PTGX

Protagonist Therapeutics Inc · Q2 2023 earnings

Q2 2023 earnings · · Investor relations

Briefing

Protagonist reported positive topline results from the Phase 2b FRONTIER 1 study of JNJ-2113 and made strides in the clinical development of rusfertide in polycythemia vera.

Protagonist Therapeutics reported positive data from the FRONTIER 1 and REVIVE studies, with JNJ-2113 advancing to Phase 3 and rusfertide's Phase 3 VERIFY study continuing. The company's cash position is strong, with runway through the end of 2025.

  • Positive topline results from the Phase 2b FRONTIER 1 study of JNJ-2113 were presented at the World Congress of Dermatology.
  • JNJ-2113 is advancing toward a Phase 3 study in psoriasis and a Phase 2b study in ulcerative colitis.
  • Positive data from the Phase 2 REVIVE study of rusfertide in polycythemia vera were presented at the European Hematology Association (EHA2023).
  • The global Phase 3 VERIFY study of rusfertide is ongoing, with enrollment completion projected by the end of the first quarter of 2024.

Headline financials

Total Revenue

$0.00

Previous: $859K-100.0%
EPS (adj)

-$0.68

Previous: -$0.84+19.0%
Capital Expenditures

-$186K

Previous: -$563K+67.0%
Free Cash Flow

-$38.6M

Previous: -$41.6M+7.1%
Net Income

-$38.5M

Previous: -$41M+6.3%
Operating Income

-$42.4M

Previous: -$41.4M-2.2%
Cash & Equivalents

$0.00

Previous: $120M-100.0%
Total Assets

$320M

Previous: $311M+3.2%
Stock-Based Comp

$8.34M

Previous: $6.81M+22.6%

Revenue & EPS history

Protagonist · Revenue · Quarterly

$0

Q2 2023-100%vs Q2 2022
Beat estimate in 6 of 13 quarters(46%)
ActualEstimate

Forward guidance

Protagonist anticipates continued progress in the clinical development of JNJ-2113 and rusfertide, with potential milestone payments and a strong cash runway.

Tailwinds

  • Potential benefits of JNJ-2113
  • Expectations regarding the clinical development of JNJ-2113
  • Potential receipt of milestone and royalty payments under collaboration agreement with Janssen Biotech, Inc.
  • Forecasted cash runway
  • Expectations regarding enrollment in the REVIVE Phase 3 trial

Headwinds

  • Ability to develop and commercialize product candidates
  • Ability to earn milestone payments under collaboration agreement with Janssen Biotech, Inc.
  • Ability to use and expand programs to build a pipeline of product candidates
  • Ability to obtain and maintain regulatory approval of product candidates
  • Ability to operate in a competitive industry and compete successfully against competitors that have greater resources

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2023

Historical avgQ2 2023

+3.2%

Avg return

Earnings day

+5.4%

Avg return

5 days after

+8.3%

Avg return

30 days after

51%

20 / 39 earnings

Positive

+75.1%

Q1 2020

Best reaction

-21.2%

Q1 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.2%+3.3%
Q4 2025-0.3%+7.8%+13.3%
Q3 2025-0.2%+6.4%+12.4%
Q1 2025+2.4%+3.2%+22.9%
Q4 2024-7.1%-6.2%+35.6%
Q3 2024-2.9%-9.3%-11.6%
Q2 2024+0.0%+8.2%+17.4%
Q1 2024+4.0%+8.3%+30.5%
Q4 2023+3.0%+8.9%-2.0%
Q3 2023+10.2%+9.0%+22.8%
Q2 2023+3.3%-2.0%+5.2%
Q1 2023+1.5%+3.3%+15.3%
Q4 2022-8.4%-9.9%-25.9%
Q3 2022-0.5%+9.4%+0.4%
Q2 2022+2.2%-1.6%-21.1%
Q1 2022-0.3%-10.3%-6.4%
Q4 2021+7.2%-0.7%-2.3%
Q3 2021+5.0%+7.4%+0.1%
Q2 2021-2.2%-0.4%-0.8%
Q1 2021-0.4%-0.1%+19.3%
Q4 2020+3.5%+2.8%-11.4%
Q3 2020+14.2%+6.6%+11.0%
Q2 2020+8.3%+2.3%+23.8%
Q1 2020+75.1%+97.4%+98.0%
Q4 2019-4.8%+5.1%-7.6%
Q3 2019-19.3%-14.2%-37.5%
Q2 2019+0.8%-2.9%+60.6%
Q1 2019+20.8%+16.3%+31.4%
Q4 2018+0.1%+22.3%+22.2%
Q3 2018+14.1%+22.3%-14.6%
Q2 2018-1.8%-6.4%-18.1%
Q1 2018-21.2%-22.4%-13.5%
Q4 2017-2.0%+1.4%-57.5%
Q3 2017+8.9%+16.2%+25.2%
Q2 2017-7.7%-4.4%+33.6%
Q1 2017+10.5%+14.3%+21.1%
Q4 2016-0.6%+0.4%-16.8%
Q3 2016-1.6%+3.4%-16.5%
Q2 2016+9.4%+19.1%+63.8%
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015

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