NASDAQ$PTGX
Protagonist Therapeutics Inc · Q4 2020 earnings
Q4 2020 earnings · · Investor relations
Briefing
Protagonist Therapeutics reported financial results for the fourth quarter and full year ended December 31, 2020.
Protagonist Therapeutics reported its Q4 and full year 2020 financial results, highlighting a year of growth with a focus on expanding the pipeline and advancing development molecules in multiple clinical programs. Key developments include positive interim data from the Phase 2 trial of rusfertide for polycythemia vera and progress with PN-943 for ulcerative colitis. The company also added new assets to the oral IL-23 receptor antagonist program and anticipates a strong cash position to fund operations through mid-2024.
- Released compelling interim data from Phase 2 trial of rusfertide for polycythemia vera.
- Expect to complete regulatory interactions and finalize registrational clinical development plan for rusfertide in the first half of 2021.
- Expect to announce initial results of the hereditary hemochromatosis proof-of-concept trial in the second half of 2021 and select an additional indication for rusfertide in 2021.
- Continued progress with Phase 2 IDEAL trial of PN-943 in ulcerative colitis, expecting completion in 2022.
Headline financials
Revenue & EPS history
Protagonist · Revenue · Quarterly
$5.65M
Forward guidance
Protagonist Therapeutics anticipates regulatory guidance in the first half of 2021 for the registrational clinical development plan of rusfertide and expects to share findings from the ongoing hereditary hemochromatosis study for rusfertide in the second half of 2021.
Tailwinds
- Anticipate regulatory guidance in the first half of 2021 for rusfertide's clinical development plan.
- Expect to share findings from the hereditary hemochromatosis study for rusfertide in the second half of 2021.
- Strong cash position to fund planned operations through the first half of 2024.
- Focusing capital to continue building value across the portfolio.
- Advancing development molecules in multiple clinical programs and indications.
Headwinds
- Potential delays in clinical trial timelines.
- Uncertainties in regulatory approval processes.
- Risks associated with drug development and commercialization.
- Competition from other companies in the industry.
- Impact of the COVID-19 pandemic on discovery and development efforts.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2020
+3.2%
Avg return
Earnings day
+5.4%
Avg return
5 days after
+8.3%
Avg return
30 days after
51%
20 / 39 earnings
Positive
+75.1%
Q1 2020
Best reaction
-21.2%
Q1 2018
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -0.3% | -0.2% | +3.3% | |
| Q4 2025 | -0.3% | +7.8% | +13.3% | |
| Q3 2025 | -0.2% | +6.4% | +12.4% | |
| Q1 2025 | +2.4% | +3.2% | +22.9% | |
| Q4 2024 | -7.1% | -6.2% | +35.6% | |
| Q3 2024 | -2.9% | -9.3% | -11.6% | |
| Q2 2024 | +0.0% | +8.2% | +17.4% | |
| Q1 2024 | +4.0% | +8.3% | +30.5% | |
| Q4 2023 | +3.0% | +8.9% | -2.0% | |
| Q3 2023 | +10.2% | +9.0% | +22.8% | |
| Q2 2023 | +3.3% | -2.0% | +5.2% | |
| Q1 2023 | +1.5% | +3.3% | +15.3% | |
| Q4 2022 | -8.4% | -9.9% | -25.9% | |
| Q3 2022 | -0.5% | +9.4% | +0.4% | |
| Q2 2022 | +2.2% | -1.6% | -21.1% | |
| Q1 2022 | -0.3% | -10.3% | -6.4% | |
| Q4 2021 | +7.2% | -0.7% | -2.3% | |
| Q3 2021 | +5.0% | +7.4% | +0.1% | |
| Q2 2021 | -2.2% | -0.4% | -0.8% | |
| Q1 2021 | -0.4% | -0.1% | +19.3% | |
| Q4 2020 | +3.5% | +2.8% | -11.4% | |
| Q3 2020 | +14.2% | +6.6% | +11.0% | |
| Q2 2020 | +8.3% | +2.3% | +23.8% | |
| Q1 2020 | +75.1% | +97.4% | +98.0% | |
| Q4 2019 | -4.8% | +5.1% | -7.6% | |
| Q3 2019 | -19.3% | -14.2% | -37.5% | |
| Q2 2019 | +0.8% | -2.9% | +60.6% | |
| Q1 2019 | +20.8% | +16.3% | +31.4% | |
| Q4 2018 | +0.1% | +22.3% | +22.2% | |
| Q3 2018 | +14.1% | +22.3% | -14.6% | |
| Q2 2018 | -1.8% | -6.4% | -18.1% | |
| Q1 2018 | -21.2% | -22.4% | -13.5% | |
| Q4 2017 | -2.0% | +1.4% | -57.5% | |
| Q3 2017 | +8.9% | +16.2% | +25.2% | |
| Q2 2017 | -7.7% | -4.4% | +33.6% | |
| Q1 2017 | +10.5% | +14.3% | +21.1% | |
| Q4 2016 | -0.6% | +0.4% | -16.8% | |
| Q3 2016 | -1.6% | +3.4% | -16.5% | |
| Q2 2016 | +9.4% | +19.1% | +63.8% | |
| Q1 2016 | — | — | — | |
| Q4 2015 | — | — | — | |
| Q3 2015 | — | — | — | |
| Q2 2015 | — | — | — | |
| Q1 2015 | — | — | — |
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