NASDAQ$ETNB

89Bio Inc · Q2 2021 earnings

Q2 2021 earnings · · Investor relations

Briefing

89bio reported financial results for the second quarter of 2021 and provided a corporate update.

89bio reported a net loss of $20.7 million for the quarter ended June 30, 2021. The company had cash, cash equivalents, and short-term investments of $171.0 million as of June 30, 2021. The company initiated Phase 2b ENLIVEN trial in NASH patients and completed enrollment in NASH histology cohort.

  • Initiated Phase 2b ENLIVEN trial in NASH patients.
  • Completed target enrollment of 20 patients in open-label histology cohort in biopsy-confirmed fibrosis stage F2 – F3 NASH patients.
  • Planning to initiate a pharmacokinetic study in NASH patients with compensated cirrhosis in 3Q21.
  • Topline data from the Phase 2 ENTRIGUE trial in severe hypertriglyceridemia patients expected in the first half of 2022.

Headline financials

EPS (adj)

-$1.03

Previous: -$0.85-21.2%
Research and Development Expenses

$15.6M

No prior period
General and Administrative Expenses

$4.92M

No prior period
Capital Expenditures

$16K

No prior period
Free Cash Flow

-$20.1M

No prior period
Net Income

-$20.7M

No prior period
Operating Income

-$20.6M

No prior period
Cash & Equivalents

$171M

No prior period
Total Assets

$182M

No prior period
Stock-Based Comp

$2.42M

No prior period

Revenue & EPS history

89Bio · Revenue · Quarterly

$0

Q1 2025
Beat estimate in 0 of 2 quarters(0%)
ActualEstimate

Forward guidance

89bio is focused on advancing BIO89-100 for NASH and severe hypertriglyceridemia, with multiple clinical trials underway and data readouts expected in the near future.

Tailwinds

  • Initiated ENLIVEN Phase 2b trial of BIO89-100 for the treatment of NASH.
  • Completed target enrollment in open-label histology cohort in biopsy-confirmed NASH patients.
  • Initiate Pharmacokinetic (PK) study in NASH patients with compensated cirrhosis (fibrosis stage F4) in 3Q21.
  • Report topline data from the Phase 2 ENTRIGUE trial of BIO89-100 in severe hypertriglyceridemia patients in the first half of 2022.
  • Strengthened leadership team with key hires across different functions.

Headwinds

  • Expectations regarding the timing and outcome of 89bio’s initiation of the Phase 2b ENLIVEN trial in NASH and Phase 2 ENTRIGUE trial in SHTG.
  • Expectations regarding the timing of topline data.
  • 89bio’s ability to execute on its strategy.
  • Positive results from a clinical study may not necessarily be predictive of the results of future or ongoing clinical studies.
  • The effect of the COVID-19 pandemic on 89bio’s clinical trials and business operations, and the impact of general economic, health, industrial or political conditions in the United States or internationally.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 7 quarterly earnings reports

Historical avg

-0.1%

Avg return

Earnings day

-4.6%

Avg return

5 days after

-2.8%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+14.8%

Q4 2019

Best reaction

-19.4%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025
Q2 2025+1.7%+1.3%-1.7%
Q1 2025-3.7%-4.1%+18.6%
Q4 2024-1.0%-7.1%-3.7%
Q3 2024+2.8%-10.9%-20.6%
Q2 2024-10.9%-11.8%-0.9%
Q1 2024-3.5%+0.8%-10.2%
Q4 2023+7.3%-0.2%-1.3%
Q3 2023-11.8%
Q2 2023+5.3%
Q1 2023+1.3%
Q4 2022-1.1%
Q3 2022+14.2%
Q2 2022+3.6%
Q1 2022+14.6%
Q4 2021+5.1%
Q3 2021+1.4%
Q2 2021+1.1%
Q1 2021-19.4%
Q4 2020-4.7%
Q3 2020-0.8%
Q2 2020+1.6%
Q1 2020-6.2%
Q4 2019+14.8%
Q3 2019-13.5%
Q2 2019
Q1 2019
Q4 2018
Q3 2018

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