NASDAQ$ETNB

89Bio Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

89Bio reported Q4 2021 financial results and provided a corporate update.

89Bio reported positive topline data from its Phase 1b/2a NASH trial and closed enrollment in the Phase 2 ENTRIGUE trial in SHTG. The company's cash, cash equivalents, and short-term investments totaled $150.7 million as of December 31, 2021.

  • Reported positive topline results from cohort 7 in the Phase 1b/2a trial demonstrating the therapeutic utility of pegozafermin for NASH treatment.
  • ENLIVEN Phase 2b NASH trial is on track for topline data in the first half of 2023.
  • Closed enrollment in the Phase 2 ENTRIGUE trial of pegozafermin in SHTG patients, with topline data expected in the second quarter of 2022.
  • Pegozafermin significantly increased adiponectin (+87%) at week 20 compared to baseline.

Headline financials

EPS (adj)

-$1.30

Previous: -$0.63-106.3%
Research and Development Expenses

$21M

No prior period
General and Administrative Expenses

$5.3M

No prior period
Capital Expenditures

$27K

No prior period
Free Cash Flow

-$28.3M

No prior period
Net Income

-$26.3M

Previous: -$12.6M-109.0%
Operating Income

-$26.2M

Previous: -$12.5M-109.1%
Cash & Equivalents

$151M

Previous: $205M-26.4%
Total Assets

$162M

Previous: $211M-23.0%
Stock-Based Comp

$2.15M

No prior period

Revenue & EPS history

89Bio · Revenue · Quarterly

$0

Q1 2025
Beat estimate in 0 of 2 quarters(0%)
ActualEstimate

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 7 quarterly earnings reports

Historical avg

-0.1%

Avg return

Earnings day

-4.6%

Avg return

5 days after

-2.8%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+14.8%

Q4 2019

Best reaction

-19.4%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025
Q2 2025+1.7%+1.3%-1.7%
Q1 2025-3.7%-4.1%+18.6%
Q4 2024-1.0%-7.1%-3.7%
Q3 2024+2.8%-10.9%-20.6%
Q2 2024-10.9%-11.8%-0.9%
Q1 2024-3.5%+0.8%-10.2%
Q4 2023+7.3%-0.2%-1.3%
Q3 2023-11.8%
Q2 2023+5.3%
Q1 2023+1.3%
Q4 2022-1.1%
Q3 2022+14.2%
Q2 2022+3.6%
Q1 2022+14.6%
Q4 2021+5.1%
Q3 2021+1.4%
Q2 2021+1.1%
Q1 2021-19.4%
Q4 2020-4.7%
Q3 2020-0.8%
Q2 2020+1.6%
Q1 2020-6.2%
Q4 2019+14.8%
Q3 2019-13.5%
Q2 2019
Q1 2019
Q4 2018
Q3 2018

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