NASDAQ$ETNB

89Bio Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

89Bio reported financial results for Q3 2022 and provided a corporate update.

89bio reported a net loss of $26.8 million for the third quarter ended September 30, 2022. The company's cash, cash equivalents, and short-term investments totaled $193.3 million as of September 30, 2022. Enrollment was completed in the ENLIVEN Phase 2b NASH trial, with topline data expected in Q1 2023.

  • Completed enrollment in ENLIVEN Phase 2b NASH trial with topline data expected in the first quarter of 2023.
  • Presented additional post-hoc exploratory analyses from the Phase 1b/2a NASH study of pegozafermin at AASLD The Liver Meeting® 2022.
  • Reported additional positive data from ENTRIGUE Phase 2 trial of pegozafermin in severe hypertriglyceridemia patients at European Society of Cardiology Congress 2022.
  • Initiation of Phase 3 trial of pegozafermin in SHTG patients expected in the first half of 2023.

Headline financials

EPS (adj)

-$0.57

Previous: -$1.41+59.6%
Free Cash Flow

-$14.8M

Previous: -$13.5M-10.0%
Net Income

-$26.8M

Previous: -$28.3M+5.4%
Operating Income

-$27M

Previous: -$28.2M+4.2%
Cash & Equivalents

$193M

Previous: $157M+22.8%
Total Assets

$201M

Previous: $168M+19.4%
Stock-Based Comp

$2.5M

Previous: $2.31M+8.0%

Revenue & EPS history

89Bio · Revenue · Quarterly

$0

Q1 2025
Beat estimate in 0 of 2 quarters(0%)
ActualEstimate

Forward guidance

89bio anticipates several milestones, including topline data from the ENLIVEN Phase 2b trial in Q1 2023 and initiation of a Phase 3 trial in SHTG in the first half of 2023.

Tailwinds

  • Pegozafermin has therapeutic potential and clinical benefits.
  • Pegozafermin has a positive clinical benefit, safety and tolerability profile.
  • Phase 2b ENLIVEN trial is underway.
  • Topline data for the ENLIVEN trial is expected.
  • Phase 3 trial in SHTG is expected to be initiated.

Headwinds

  • The timing and outcome of the Phase 2b ENLIVEN trial in NASH are uncertain.
  • The timing of topline data is uncertain.
  • The initiation of the Phase 3 trial in SHTG is uncertain.
  • 89bio's ability to execute on its strategy is not guaranteed.
  • Positive results from a clinical study may not be predictive of future results.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 7 quarterly earnings reports

Historical avg

-0.1%

Avg return

Earnings day

-4.6%

Avg return

5 days after

-2.8%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+14.8%

Q4 2019

Best reaction

-19.4%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025
Q2 2025+1.7%+1.3%-1.7%
Q1 2025-3.7%-4.1%+18.6%
Q4 2024-1.0%-7.1%-3.7%
Q3 2024+2.8%-10.9%-20.6%
Q2 2024-10.9%-11.8%-0.9%
Q1 2024-3.5%+0.8%-10.2%
Q4 2023+7.3%-0.2%-1.3%
Q3 2023-11.8%
Q2 2023+5.3%
Q1 2023+1.3%
Q4 2022-1.1%
Q3 2022+14.2%
Q2 2022+3.6%
Q1 2022+14.6%
Q4 2021+5.1%
Q3 2021+1.4%
Q2 2021+1.1%
Q1 2021-19.4%
Q4 2020-4.7%
Q3 2020-0.8%
Q2 2020+1.6%
Q1 2020-6.2%
Q4 2019+14.8%
Q3 2019-13.5%
Q2 2019
Q1 2019
Q4 2018
Q3 2018

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