NASDAQ$ETNB

89Bio Inc · Q1 2021 earnings

Q1 2021 earnings · · Investor relations

Briefing

Reported financial results for the first quarter of 2021 and provided a corporate update.

89bio reported its Q1 2021 financial results, highlighting the FDA's written guidance on the Phase 2b ENLIVEN trial design for NASH and a cash position of $189.6 million as of March 31, 2021.

  • Received FDA guidance on Phase 2b ENLIVEN trial design for NASH, planned to initiate in Q2 2021.
  • Topline data from the paired-biopsy, open-label histology cohort in NASH patients expected by year-end 2021.
  • Topline data from the Phase 2 ENTRIGUE trial in severe hypertriglyceridemia patients expected in 2H21.
  • Cash, cash equivalents, and short-term investments totaled $189.6 million as of March 31, 2021.

Headline financials

EPS (adj)

-$0.74

Previous: -$0.76+2.6%
Net Loss Per Share, Basic and Diluted

$0.74

No prior period
Net Income

-$14.8M

Previous: -$10.5M-40.2%
Operating Income

-$14.7M

No prior period
Cash & Equivalents

$190M

Previous: $85.5M+121.7%
Total Assets

$199M

Previous: $87.7M+126.5%

Revenue & EPS history

89Bio · Revenue · Quarterly

$0

Q1 2025
Beat estimate in 0 of 2 quarters(0%)
ActualEstimate

Forward guidance

89bio anticipates several milestones, including initiating the ENLIVEN Phase 2b trial in NASH, reporting topline data from the paired-biopsy cohort in NASH patients, and reporting topline data from the ENTRIGUE Phase 2 trial in severe hypertriglyceridemia patients.

Tailwinds

  • Initiate Phase 2b ENLIVEN trial in NASH in Q2 2021.
  • Report topline data from paired-biopsy, open-label histology cohort in NASH patients by year-end 2021.
  • Report topline data from Phase 2 ENTRIGUE trial in severe hypertriglyceridemia patients in 2H21.
  • BIO89-100 has potential in both NASH and severe hypertriglyceridemia (SHTG).
  • Well-funded to reach multiple clinical and regulatory milestones.

Headwinds

  • COVID-19 surge in Europe has resulted in enrollment challenges in certain geographies for the ENTRIGUE trial.
  • The timing and outcome of 89bio’s initiation of the Phase 2b ENLIVEN trial in NASH and Phase 2 ENTRIGUE trial in SHTG are uncertain.
  • Expectations regarding the timing of topline data are uncertain.
  • Positive results from a clinical study may not necessarily be predictive of the results of future or ongoing clinical studies.
  • The effect of the COVID-19 pandemic on 89bio’s clinical trials and business operations is uncertain.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 7 quarterly earnings reports

Historical avg

-0.1%

Avg return

Earnings day

-4.6%

Avg return

5 days after

-2.8%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+14.8%

Q4 2019

Best reaction

-19.4%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025
Q2 2025+1.7%+1.3%-1.7%
Q1 2025-3.7%-4.1%+18.6%
Q4 2024-1.0%-7.1%-3.7%
Q3 2024+2.8%-10.9%-20.6%
Q2 2024-10.9%-11.8%-0.9%
Q1 2024-3.5%+0.8%-10.2%
Q4 2023+7.3%-0.2%-1.3%
Q3 2023-11.8%
Q2 2023+5.3%
Q1 2023+1.3%
Q4 2022-1.1%
Q3 2022+14.2%
Q2 2022+3.6%
Q1 2022+14.6%
Q4 2021+5.1%
Q3 2021+1.4%
Q2 2021+1.1%
Q1 2021-19.4%
Q4 2020-4.7%
Q3 2020-0.8%
Q2 2020+1.6%
Q1 2020-6.2%
Q4 2019+14.8%
Q3 2019-13.5%
Q2 2019
Q1 2019
Q4 2018
Q3 2018

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