NASDAQ$ETNB

89Bio Inc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

89bio's financial results for Q1 2024 were reported, along with a corporate update.

89bio reported a net loss of $51.7 million for the first quarter of 2024. The company initiated the Phase 3 ENLIGHTEN-Fibrosis trial and expects to initiate the ENLIGHTEN-Cirrhosis trial this quarter. They also received PRIME status from the EMA for pegozafermin in MASH treatment.

  • Initiated Phase 3 ENLIGHTEN-Fibrosis trial in non-cirrhotic MASH patients.
  • Expect to initiate ENLIGHTEN-Cirrhosis trial this quarter in MASH patients with compensated cirrhosis.
  • Granted PRIME status from EMA for pegozafermin in treating MASH with fibrosis and compensated cirrhosis.
  • Data from the 48-Week Extension Phase of the ENLIVEN Phase 2b Trial to be presented at EASL.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.54

Previous: -$0.54+0.0%
Net Income

-$51.7M

Previous: -$28.8M-79.2%
Operating Income

-$57.3M

Previous: -$28.5M-100.8%
Gross Profit

$0.00

No prior period
R&D Expense

$47.4M

No prior period
Stock-Based Comp

$5M

Previous: $3.55M+40.7%

Revenue & EPS history

89Bio · Revenue · Quarterly

$0

Q1 2024
Beat estimate in 0 of 2 quarters(0%)
ActualEstimate

Forward guidance

89bio anticipates topline data from the ENTRUST Phase 3 trial in SHTG in 2025 and is focused on executing Phase 3 trials for MASH.

Tailwinds

  • On track to begin the ENLIGHTEN-Cirrhosis trial for compensated cirrhotic MASH patients in the second quarter.
  • Pegozafermin has the potential to be the leading therapy in treating advanced MASH patients with fibrosis.
  • Focused on the execution of Phase 3 trials for MASH and the synergistic Phase 3 trial in severe hypertriglyceridemia (SHTG).
  • Agreement for commercial supply is designed to strategically enhance readiness for potential commercialization.
  • Enrollment continues to progress well in ENTRUST, the Phase 3 trial evaluating the efficacy, safety, and tolerability of pegozafermin in patients with SHTG.

Headwinds

  • Trial outcomes are subject to various risks and uncertainties.
  • Positive results from a clinical study may not necessarily be predictive of the results of future or ongoing clinical studies.
  • Substantial dependence on the success of lead product candidate.
  • Competition from competing products.
  • Impact of general economic, health, industrial or political conditions.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 7 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

-0.1%

Avg return

Earnings day

-4.6%

Avg return

5 days after

-2.8%

Avg return

30 days after

54%

13 / 24 earnings

Positive

+14.8%

Q4 2019

Best reaction

-19.4%

Q1 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025
Q2 2025+1.7%+1.3%-1.7%
Q1 2025-3.7%-4.1%+18.6%
Q4 2024-1.0%-7.1%-3.7%
Q3 2024+2.8%-10.9%-20.6%
Q2 2024-10.9%-11.8%-0.9%
Q1 2024-3.5%+0.8%-10.2%
Q4 2023+7.3%-0.2%-1.3%
Q3 2023-11.8%
Q2 2023+5.3%
Q1 2023+1.3%
Q4 2022-1.1%
Q3 2022+14.2%
Q2 2022+3.6%
Q1 2022+14.6%
Q4 2021+5.1%
Q3 2021+1.4%
Q2 2021+1.1%
Q1 2021-19.4%
Q4 2020-4.7%
Q3 2020-0.8%
Q2 2020+1.6%
Q1 2020-6.2%
Q4 2019+14.8%
Q3 2019-13.5%
Q2 2019
Q1 2019
Q4 2018
Q3 2018

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