NASDAQ$DAWN
Day One Biopharmaceuticals Inc · Q4 2025 earnings
Q4 2025 earnings · · After market close · Investor relations
Briefing
Day One Biopharmaceuticals reported Q4 2025, revenue of $52.8M, net loss of $40M.
For Q4 2025, Day One Biopharmaceuticals reported revenue of $52.8M, a net loss of $40M. Management discusses segment performance, capital allocation, and outlook in the earnings release.
- Revenue $52.8M.
- Net loss $40M.
- Day One Biopharmaceuticals highlights liquidity, operations, and 2026 priorities.
Headline financials
Revenue & EPS history
Day One · Revenue · Quarterly
$52.8M
Forward guidance
The release discusses Day One Biopharmaceuticals's outlook for upcoming periods, including capital allocation, operating priorities, and market risks, without relying solely on numeric EPS bridges.
Tailwinds
- Day One Biopharmaceuticals cites operational execution and demand trends supporting the outlook.
- Balance sheet and liquidity actions aim to fund growth and returns.
Headwinds
- GAAP profitability remained under pressure in Q4 2025.
- Macro, pricing, and input-cost volatility could pressure margins.
- Segment mix and one-time items may affect quarter-to-quarter comparability.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2025
-1.4%
Avg return
Earnings day
-2.1%
Avg return
5 days after
+1.2%
Avg return
30 days after
45%
9 / 20 earnings
Positive
+23.6%
Q2 2022
Best reaction
-16.6%
Q4 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2025 | -9.2% | -13.9% | +78.0% | |
| Q3 2025 | +0.0% | +3.7% | +34.8% | |
| Q2 2025 | -15.4% | -14.2% | +9.7% | |
| Q1 2025 | -9.6% | -5.9% | +2.9% | |
| Q4 2024 | -16.5% | -30.2% | -31.7% | |
| Q3 2024 | +2.6% | +3.2% | -2.9% | |
| Q2 2024 | -6.8% | -9.4% | -11.0% | |
| Q1 2024 | -0.5% | -6.8% | -23.9% | |
| Q4 2023 | +14.5% | +15.0% | +4.0% | |
| Q3 2023 | -3.1% | -11.1% | -3.7% | |
| Q2 2023 | +1.3% | +4.3% | +9.6% | |
| Q1 2023 | +12.7% | +10.3% | +7.3% | |
| Q4 2022 | +5.3% | -4.2% | -32.8% | |
| Q3 2022 | +2.7% | +10.6% | +14.3% | |
| Q2 2022 | +23.6% | +18.9% | +24.4% | |
| Q1 2022 | +8.5% | +21.8% | -6.1% | |
| Q4 2021 | +3.7% | -3.8% | -6.9% | |
| Q3 2021 | -9.2% | -15.7% | -31.7% | |
| Q2 2021 | -16.6% | -7.6% | -5.2% | |
| Q4 2020 | -16.6% | -7.6% | -5.2% | |
| Q1 2021 | — | — | — | |
| Q3 2020 | — | — | — | |
| Q2 2020 | — | — | — | |
| Q1 2020 | — | — | — |
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