NASDAQ$DAWN

Day One Biopharmaceuticals Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Announced fourth quarter and full year 2022 financial results and highlighted recent corporate achievements.

Day One Biopharmaceuticals reported its Q4 and full year 2022 financial results, highlighting the first patient dosed in the pivotal Phase 3 FIREFLY-2/LOGGIC trial and positive topline data from the Phase 2 FIREFLY-1 trial.

  • First patient dosed in pivotal Phase 3 FIREFLY-2/LOGGIC trial evaluating tovorafenib (DAY101) as a frontline therapy for patients newly diagnosed with pediatric low-grade glioma (pLGG).
  • Reported topline data in January 2023 from ongoing, pivotal Phase 2 FIREFLY-1 trial demonstrating meaningful responses with tovorafenib (DAY101) in relapsed or progressive pLGG.
  • Additional data from FIREFLY-1 planned for presentation at a medical meeting in second quarter of 2023.
  • New Drug Application (NDA) submission planned for tovorafenib (DAY101) in first half of 2023.

Headline financials

EPS (adj)

-$0.53

Previous: $0.36-247.2%
Free Cash Flow

-$35.3M

Previous: -$13.2M-168.1%
Operating Income

-$42.7M

Previous: -$122M+64.9%
Cash & Equivalents

$342M

Previous: $284M+20.4%
Total Assets

$349M

Previous: $290M+20.4%

Revenue & EPS history

Day One · Revenue · Quarterly

$52.8M

Q4 2025-59.7%vs Q4 2024
Beat estimate in 6 of 6 quarters(100%)
ActualEstimate

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-1.4%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+1.2%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+23.6%

Q2 2022

Best reaction

-16.6%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-9.2%-13.9%+78.0%
Q3 2025+0.0%+3.7%+34.8%
Q2 2025-15.4%-14.2%+9.7%
Q1 2025-9.6%-5.9%+2.9%
Q4 2024-16.5%-30.2%-31.7%
Q3 2024+2.6%+3.2%-2.9%
Q2 2024-6.8%-9.4%-11.0%
Q1 2024-0.5%-6.8%-23.9%
Q4 2023+14.5%+15.0%+4.0%
Q3 2023-3.1%-11.1%-3.7%
Q2 2023+1.3%+4.3%+9.6%
Q1 2023+12.7%+10.3%+7.3%
Q4 2022+5.3%-4.2%-32.8%
Q3 2022+2.7%+10.6%+14.3%
Q2 2022+23.6%+18.9%+24.4%
Q1 2022+8.5%+21.8%-6.1%
Q4 2021+3.7%-3.8%-6.9%
Q3 2021-9.2%-15.7%-31.7%
Q2 2021-16.6%-7.6%-5.2%
Q4 2020-16.6%-7.6%-5.2%
Q1 2021
Q3 2020
Q2 2020
Q1 2020

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