NASDAQ$DAWN

Day One Biopharmaceuticals Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Announced first quarter 2022 financial results and provided a business update.

Day One Biopharmaceuticals reported first quarter 2022 financial results. The company's cash and cash equivalents totaled $262.7 million. Net loss totaled $27.7 million for the quarter.

  • Initial data from pivotal FIREFLY-1 study with tovorafenib (DAY101) in relapsed pediatric low-grade glioma (pLGG) expected in June 2022
  • Company plans to initiate pivotal Phase 3 FIREFLY-2 clinical trial evaluating tovorafenib as a first-line therapy in pLGG in the second quarter of 2022
  • Initiated Phase 1b/2 combination study with tovorafenib and pimasertib in RAF-altered solid tumors
  • Day One anticipates releasing topline results from the fully-enrolled pivotal study in the first quarter of 2023.

Headline financials

EPS (adj)

-$0.48

Previous: -$0.25-90.8%
Capital Expenditures

$15K

No prior period
Free Cash Flow

-$21.6M

No prior period
Net Income

-$27.7M

Previous: -$15.2M-82.8%
Operating Income

-$27.7M

Previous: -$16.1M-72.5%
Cash & Equivalents

$263M

No prior period
Total Assets

$268M

No prior period

Revenue & EPS history

Day One · Revenue · Quarterly

$52.8M

Q4 2025-59.7%vs Q4 2024
Beat estimate in 6 of 6 quarters(100%)
ActualEstimate

Forward guidance

Management believes it has sufficient capital resources to fund anticipated operations into 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-1.4%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+1.2%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+23.6%

Q2 2022

Best reaction

-16.6%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-9.2%-13.9%+78.0%
Q3 2025+0.0%+3.7%+34.8%
Q2 2025-15.4%-14.2%+9.7%
Q1 2025-9.6%-5.9%+2.9%
Q4 2024-16.5%-30.2%-31.7%
Q3 2024+2.6%+3.2%-2.9%
Q2 2024-6.8%-9.4%-11.0%
Q1 2024-0.5%-6.8%-23.9%
Q4 2023+14.5%+15.0%+4.0%
Q3 2023-3.1%-11.1%-3.7%
Q2 2023+1.3%+4.3%+9.6%
Q1 2023+12.7%+10.3%+7.3%
Q4 2022+5.3%-4.2%-32.8%
Q3 2022+2.7%+10.6%+14.3%
Q2 2022+23.6%+18.9%+24.4%
Q1 2022+8.5%+21.8%-6.1%
Q4 2021+3.7%-3.8%-6.9%
Q3 2021-9.2%-15.7%-31.7%
Q2 2021-16.6%-7.6%-5.2%
Q4 2020-16.6%-7.6%-5.2%
Q1 2021
Q3 2020
Q2 2020
Q1 2020

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