NASDAQ$DAWN

Day One Biopharmaceuticals Inc · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Day One Biopharmaceuticals reported Q1 2025, revenue of $30.8M, net loss of $36M, diluted EPS of $-0.35.

For Q1 2025, Day One Biopharmaceuticals reported revenue of $30.8M, a net loss of $36M, diluted EPS was $-0.35. Management discusses operating trends, capital, and sector risks in the quarterly filing.

  • Q1 2025 revenue $30.8M.
  • Net loss $36M.
  • Diluted EPS $-0.35.

Headline financials

Total Revenue

$30.8M

Previous: $0.00
EPS (adj)

-$0.35

Previous: -$0.72+51.4%
R&D Expenses

$39.6M

Previous: $40.2M-1.5%
SG&A Expenses

$29.3M

Previous: $26.6M+10.4%
Capital Expenditures

-$317K

Previous: $0.00
Net Income

-$36M

Previous: -$62.4M+42.3%
Operating Income

-$41.1M

Previous: -$66.8M+38.5%

Revenue & EPS history

Day One · Revenue · Quarterly

$30.8M

Q1 2025
Beat estimate in 6 of 6 quarters(100%)
ActualEstimate

Forward guidance

Biotech filers emphasize pipeline milestones, regulatory events, and cash runway; GAAP earnings can be dominated by collaboration or one-time items.

Tailwinds

  • Commercial product ramps where approved.
  • Partnership funding and milestone payments.
  • Pipeline catalysts in cardiovascular and rare disease.

Headwinds

  • Trial or regulatory setback risk.
  • R&D spend ahead of revenue for pre-commercial assets.
  • Exclusivity cliffs and reimbursement pressure.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-1.4%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+1.2%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+23.6%

Q2 2022

Best reaction

-16.6%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-9.2%-13.9%+78.0%
Q3 2025+0.0%+3.7%+34.8%
Q2 2025-15.4%-14.2%+9.7%
Q1 2025-9.6%-5.9%+2.9%
Q4 2024-16.5%-30.2%-31.7%
Q3 2024+2.6%+3.2%-2.9%
Q2 2024-6.8%-9.4%-11.0%
Q1 2024-0.5%-6.8%-23.9%
Q4 2023+14.5%+15.0%+4.0%
Q3 2023-3.1%-11.1%-3.7%
Q2 2023+1.3%+4.3%+9.6%
Q1 2023+12.7%+10.3%+7.3%
Q4 2022+5.3%-4.2%-32.8%
Q3 2022+2.7%+10.6%+14.3%
Q2 2022+23.6%+18.9%+24.4%
Q1 2022+8.5%+21.8%-6.1%
Q4 2021+3.7%-3.8%-6.9%
Q3 2021-9.2%-15.7%-31.7%
Q2 2021-16.6%-7.6%-5.2%
Q4 2020-16.6%-7.6%-5.2%
Q1 2021
Q3 2020
Q2 2020
Q1 2020

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