NASDAQ$DAWN

Day One Biopharmaceuticals Inc · Q3 2021 earnings

Q3 2021 earnings · · Investor relations

Briefing

Announced third quarter 2021 financial results and corporate progress.

Day One Biopharmaceuticals reported a net loss of $19.2 million for the third quarter of 2021. The company's cash and cash equivalents totaled $297.2 million as of September 30, 2021, which is expected to fund operations into the second half of 2023.

  • FIREFLY-1, a pivotal Phase 2 clinical trial of DAY101 in pediatric low-grade glioma (pLGG), continues active enrollment; initial data are expected in the first half of 2022.
  • Day One will present a poster at the 2021 Connective Tissue Oncology Society (CTOS) Virtual Annual Meeting on November 12, 2021, highlighting single agent activity of DAY101 in Spindle Cell Carcinoma.
  • Day One is also conducting a Phase 2 monotherapy trial of DAY101 in adult patients with recurrent, progressive, or refractory solid tumors harboring MAPK pathway aberrations.
  • Day One strengthened its leadership team with appointment of Jaa Roberson as chief people officer and expanded its board of directors with the appointment of Scott Garland.

Headline financials

EPS (adj)

-$0.33

Previous: -$0.07-391.1%
R&D Expenses

$9.85M

Previous: $2.54M+288.2%
Free Cash Flow

-$12.2M

No prior period
Net Income

-$19.2M

Previous: -$2.82M-581.3%
Operating Income

-$19.2M

Previous: -$3.56M-440.3%
Cash & Equivalents

$297M

No prior period
Total Assets

$304M

No prior period

Revenue & EPS history

Day One · Revenue · Quarterly

$52.8M

Q4 2025-59.7%vs Q4 2024
Beat estimate in 3 of 3 quarters(100%)
ActualEstimate

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2021

Historical avgQ3 2021

-1.4%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+1.2%

Avg return

30 days after

45%

9 / 20 earnings

Positive

+23.6%

Q2 2022

Best reaction

-16.6%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-9.2%-13.9%+78.0%
Q3 2025+0.0%+3.7%+34.8%
Q2 2025-15.4%-14.2%+9.7%
Q1 2025-9.6%-5.9%+2.9%
Q4 2024-16.5%-30.2%-31.7%
Q3 2024+2.6%+3.2%-2.9%
Q2 2024-6.8%-9.4%-11.0%
Q1 2024-0.5%-6.8%-23.9%
Q4 2023+14.5%+15.0%+4.0%
Q3 2023-3.1%-11.1%-3.7%
Q2 2023+1.3%+4.3%+9.6%
Q1 2023+12.7%+10.3%+7.3%
Q4 2022+5.3%-4.2%-32.8%
Q3 2022+2.7%+10.6%+14.3%
Q2 2022+23.6%+18.9%+24.4%
Q1 2022+8.5%+21.8%-6.1%
Q4 2021+3.7%-3.8%-6.9%
Q3 2021-9.2%-15.7%-31.7%
Q2 2021-16.6%-7.6%-5.2%
Q4 2020-16.6%-7.6%-5.2%
Q1 2021
Q3 2020
Q2 2020
Q1 2020

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