NASDAQ$ANNX

Annexon Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Annexon reported Q1 2025 a net loss of $54.4M, diluted EPS of $-0.37.

For Q1 2025, Annexon reported net loss was $54.4M, diluted EPS was $-0.37. Management discusses segment trends, liquidity, and outlook in the quarterly filing.

  • Net loss $54.4M.
  • Diluted EPS $-0.37.
  • MD&A highlights operating priorities, liquidity, and sector risks.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$0.37

Previous: -$0.21-76.2%
R&D expenses

$48.2M

Previous: $21M+129.8%
G&A expenses

$9.23M

Previous: $7.61M+21.3%
Total operating expenses

$57.4M

Previous: $28.6M+100.9%
Interest and other income

$3.05M

Previous: $3.4M-10.2%
Wtd. avg. shares (basic & diluted)

148.1M

Previous: 122.7M+20.7%
Cash, cash equivalents & short-term investments

$264M

No prior period
Net Income

-$54.4M

Previous: -$25.2M-115.9%
Operating Income

-$57.4M

Previous: -$28.6M-100.9%

Revenue & EPS history

Annexon · Revenue · Quarterly

$0

Q1 2025

Forward guidance

Outlook emphasizes clinical milestones, liquidity runway, and cost discipline.

Tailwinds

  • Pipeline readouts and partnership economics.
  • Cash balance supports near-term development plans.

Headwinds

  • Operating losses and trial risk until commercialization.
  • Financing markets and competition affect funding costs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+3.0%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+1.8%

Avg return

30 days after

64%

14 / 22 earnings

Positive

+23.1%

Q1 2022

Best reaction

-8.1%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-6.9%-4.6%-7.4%
Q3 2025-0.7%-9.1%+69.1%
Q1 2025+9.4%+8.8%+37.6%
Q4 2024+3.3%+15.5%-23.4%
Q3 2024-6.6%-16.6%-32.2%
Q2 2024+3.8%+11.3%+12.8%
Q1 2024+1.5%-8.8%+27.2%
Q4 2023+17.6%+8.0%-30.9%
Q3 2023+16.7%+22.4%+23.8%
Q2 2023-1.2%-2.1%-26.6%
Q1 2023+4.2%+3.7%-40.7%
Q4 2022+3.8%-8.0%-15.0%
Q3 2022-0.4%+16.6%+15.8%
Q2 2022+3.1%+17.2%+10.2%
Q1 2022+23.1%+25.0%+51.2%
Q4 2021-5.1%-11.0%-43.8%
Q3 2021+1.3%+0.2%-3.4%
Q2 2021-4.6%-13.7%+11.6%
Q1 2021+1.1%+9.3%+12.6%
Q4 2020-8.1%-17.4%-29.5%
Q3 2020+3.5%+9.1%+13.0%
Q2 2020+6.6%-1.2%+8.9%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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