NASDAQ$ANNX

Annexon Inc · Q1 2021 earnings

Q1 2021 earnings · · Investor relations

Briefing

Annexon reported first quarter 2021 financial results and business highlights.

Annexon's cash and cash equivalents and short-term investments were $326.7 million as of March 31, 2021. Research and development expenses were $20.7 million for the quarter ended March 31, 2021. Net loss was $26.0 million for the quarter ended March 31, 2021.

  • Phase 2 trial of ANX005 in Huntington’s Disease (HD) fully enrolled with data anticipated 2H 2021.
  • First-in-Human dose-ranging trial of ANX009 completed with data expected summer 2021.
  • Next generation drug candidates, ANX105 and ANX1502, are on track to submit INDs by end of 2021.
  • Current cash position is sufficient to fund operations through 2023.

Headline financials

EPS (adj)

-$0.68

Previous: -$0.94+27.7%
Net Income

-$26M

Previous: -$12.3M-110.7%
Cash & Equivalents

$207M

No prior period
Total Assets

$333M

No prior period

Revenue & EPS history

Annexon · Revenue · Quarterly

$0

Q3 2025

Forward guidance

Annexon remains on track for another exciting year, and looking ahead, is sharply focused on effectively executing our several clinical programs while advancing multiple next generation drug candidates and driving our beachhead strategy to rapidly expand our platform into mechanistically related indications.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2021

Historical avgQ1 2021

+3.0%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+1.8%

Avg return

30 days after

64%

14 / 22 earnings

Positive

+23.1%

Q1 2022

Best reaction

-8.1%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-6.9%-4.6%-7.4%
Q3 2025-0.7%-9.1%+69.1%
Q1 2025+9.4%+8.8%+37.6%
Q4 2024+3.3%+15.5%-23.4%
Q3 2024-6.6%-16.6%-32.2%
Q2 2024+3.8%+11.3%+12.8%
Q1 2024+1.5%-8.8%+27.2%
Q4 2023+17.6%+8.0%-30.9%
Q3 2023+16.7%+22.4%+23.8%
Q2 2023-1.2%-2.1%-26.6%
Q1 2023+4.2%+3.7%-40.7%
Q4 2022+3.8%-8.0%-15.0%
Q3 2022-0.4%+16.6%+15.8%
Q2 2022+3.1%+17.2%+10.2%
Q1 2022+23.1%+25.0%+51.2%
Q4 2021-5.1%-11.0%-43.8%
Q3 2021+1.3%+0.2%-3.4%
Q2 2021-4.6%-13.7%+11.6%
Q1 2021+1.1%+9.3%+12.6%
Q4 2020-8.1%-17.4%-29.5%
Q3 2020+3.5%+9.1%+13.0%
Q2 2020+6.6%-1.2%+8.9%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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