NASDAQ$ANNX
Annexon Inc · Q1 2022 earnings
Q1 2022 earnings · · Investor relations
Briefing
Annexon reported first quarter 2022 financial results and highlighted portfolio progress.
Annexon reported a net loss of $35.4 million for the quarter ended March 31, 2022. The company's cash and cash equivalents were $206.7 million as of March 31, 2022, which is expected to fund operating plans into 2024. The company anticipates eight clinical catalysts across its pipeline throughout 2022 and 2023.
- Advanced five drug candidates with distinct routes of administration and dosing schedules.
- Phase 2 trial in Huntington's disease has completed the six-month treatment period and three-month follow-up period, with data anticipated in the second quarter of 2022.
- Phase 2 ARCHER trial for ANX007 fully enrolled with initial data anticipated in the first half of 2023.
- Initiated first-in-human trial of ANX105 in the second quarter of 2022, with data expected in 2023.
Headline financials
Revenue & EPS history
Annexon · Revenue · Quarterly
$400K
Forward guidance
Annexon expects its current cash position to fund its operating plans into 2024 and anticipates multiple clinical data readouts throughout 2022 and 2023.
Tailwinds
- Phase 2 trial in patients with HD has completed the six-month treatment period and three-month follow-up period, with data anticipated in the second quarter of 2022
- Phase 2 trial in patients with wAIHA was initiated, with initial data anticipated in the second half of 2022
- Phase 2/3 trial in patients with GBS is underway, with data anticipated in 2023
- Phase 2 trial in patients with ALS is underway, with data anticipated in 2023
- Initial data from Phase 1b trial in patients with LN is anticipated in the second half of 2022
Headwinds
- The company has a history of net operating losses
- The company's product candidates are in early stages of clinical development
- The company relies on third-party suppliers and manufacturers
- The company needs to obtain necessary capital to fund its clinical programs
- The company's ability to obtain regulatory approval of and successfully commercialize its product candidates
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2022
+3.0%
Avg return
Earnings day
+2.5%
Avg return
5 days after
+1.8%
Avg return
30 days after
64%
14 / 22 earnings
Positive
+23.1%
Q1 2022
Best reaction
-8.1%
Q4 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | -6.9% | -4.6% | -7.4% | |
| Q3 2025 | -0.7% | -9.1% | +69.1% | |
| Q1 2025 | +9.4% | +8.8% | +37.6% | |
| Q4 2024 | +3.3% | +15.5% | -23.4% | |
| Q3 2024 | -6.6% | -16.6% | -32.2% | |
| Q2 2024 | +3.8% | +11.3% | +12.8% | |
| Q1 2024 | +1.5% | -8.8% | +27.2% | |
| Q4 2023 | +17.6% | +8.0% | -30.9% | |
| Q3 2023 | +16.7% | +22.4% | +23.8% | |
| Q2 2023 | -1.2% | -2.1% | -26.6% | |
| Q1 2023 | +4.2% | +3.7% | -40.7% | |
| Q4 2022 | +3.8% | -8.0% | -15.0% | |
| Q3 2022 | -0.4% | +16.6% | +15.8% | |
| Q2 2022 | +3.1% | +17.2% | +10.2% | |
| Q1 2022 | +23.1% | +25.0% | +51.2% | |
| Q4 2021 | -5.1% | -11.0% | -43.8% | |
| Q3 2021 | +1.3% | +0.2% | -3.4% | |
| Q2 2021 | -4.6% | -13.7% | +11.6% | |
| Q1 2021 | +1.1% | +9.3% | +12.6% | |
| Q4 2020 | -8.1% | -17.4% | -29.5% | |
| Q3 2020 | +3.5% | +9.1% | +13.0% | |
| Q2 2020 | +6.6% | -1.2% | +8.9% | |
| Q1 2020 | — | — | — | |
| Q4 2019 | — | — | — | |
| Q3 2019 | — | — | — | |
| Q2 2019 | — | — | — | |
| Q1 2019 | — | — | — | |
| Q4 2018 | — | — | — | |
| Q3 2018 | — | — | — | |
| Q2 2018 | — | — | — | |
| Q1 2018 | — | — | — |
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