NASDAQ$ALT

Altimmune Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Altimmune reported a narrowed net loss and steady R&D progress in Q1 2025, with major clinical milestones approaching.

Altimmune maintained a focused R&D strategy in Q1 2025, reducing expenses and strengthening its balance sheet. The company is poised for significant updates in Q2 with the anticipated Phase 2b MASH data readout and new clinical trials in AUD and ALD set to launch.

  • Net loss improved to $19.6M from $24.4M in Q1 2024.
  • Cash and short-term investments totaled $150.8M as of March 31, 2025.
  • Pemvidutide Phase 2b MASH data expected in Q2 2025.
  • Phase 2 trials in Alcohol Use Disorder and Alcohol Liver Disease to begin in Q2 and Q3.

Headline financials

Total Revenue

$5K

Previous: $5K+0.0%
EPS (adj)

-$0.26

Previous: -$0.34+23.5%
Cash and Short-term Investments

$151M

No prior period
Capital Expenditures

$0.00

Previous: -$51K+100.0%
Net Income

-$19.6M

Previous: -$24.4M+19.8%
Operating Income

-$21.8M

Previous: -$26.8M+18.6%
Gross Profit

-$24K

Previous: $5K-580.0%
R&D Expense

$15.8M

Previous: $21.5M-26.5%

Revenue & EPS history

Altimmune · Revenue · Quarterly

$5K

Q1 2025+0%vs Q1 2024
Beat estimate in 9 of 12 quarters(75%)
ActualEstimate

Forward guidance

Altimmune expects pivotal trial readouts and launches in new indications to shape its pipeline and investment potential through 2025.

Tailwinds

  • Top-line MASH data from Phase 2b expected in Q2 2025.
  • High MASHResInd response rate (>90%) observed in Phase 1b analysis.
  • INDs cleared and Phase 2 trials in AUD and ALD planned for Q2/Q3.
  • $100M credit facility secured to extend financial runway.
  • Decreased R&D spend vs. Q1 2024 due to trial timing.

Headwinds

  • Minimal revenue generation during the quarter.
  • No reported commercial pipeline yet; entirely clinical-stage.
  • Net loss persists despite reduced operating expenses.
  • No non-GAAP EPS guidance provided.
  • Dependence on trial outcomes for future valuation growth.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+2.4%

Avg return

Earnings day

+1.5%

Avg return

5 days after

+5.6%

Avg return

30 days after

60%

21 / 35 earnings

Positive

+35.0%

Q2 2022

Best reaction

-25.1%

Q3 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.0%-8.8%-15.3%
Q4 2025-17.6%-9.6%-21.8%
Q3 2025+5.1%+14.1%+39.7%
Q1 2025-4.2%-7.2%+19.0%
Q4 2024+8.1%+0.3%-10.4%
Q3 2024+29.5%+3.5%+16.9%
Q2 2024+12.2%+14.7%+12.7%
Q1 2024+0.8%+9.2%-9.8%
Q4 2023+17.7%+18.3%-16.1%
Q3 2023+1.1%-6.4%+146.4%
Q2 2023+2.0%-4.7%-16.9%
Q1 2023+2.2%-6.6%-19.7%
Q4 2022+1.9%-2.0%-64.3%
Q3 2022+10.3%+12.7%+4.2%
Q2 2022+35.0%+37.3%+55.4%
Q1 2022+31.0%+34.3%+117.0%
Q4 2021+2.2%+12.1%-18.7%
Q3 2021-0.5%+1.3%-12.3%
Q2 2021+6.6%+14.9%+56.8%
Q1 2021+5.2%+4.7%+23.0%
Q4 2020-18.6%-19.5%-29.3%
Q3 2020-25.1%-18.6%-1.1%
Q2 2020-13.5%-5.5%-54.3%
Q1 2020+21.4%+21.6%+103.8%
Q4 2019-7.1%-6.5%-2.8%
Q3 2019-8.0%-10.9%-1.7%
Q2 2019-6.5%-6.5%-0.9%
Q1 2019+2.7%-4.7%-3.5%
Q4 2018+3.4%+6.6%-0.7%
Q3 2018-6.8%-9.1%-31.5%
Q2 2018+4.9%+0.3%-21.0%
Q1 2018+10.8%-1.9%+1.7%
Q4 2017-8.3%-5.9%-36.0%
Q3 2017-1.0%-7.1%-25.1%
Q2 2017-10.3%-12.0%+11.6%
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2012
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q3 2012
Q2 2012
Q1 2011
Q1 2012
Q4 2011
Q3 2011
Q2 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

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