NASDAQ$ALT
Altimmune Inc · Q1 2023 earnings
Q1 2023 earnings · · Investor relations
Briefing
Announced financial results for Q1 2023 and provided a business update.
Altimmune reported a net loss of $20.1 million, or $0.40 net loss per share, and its cash, cash equivalents and short-term investments totaled $165.8 million as of March 31, 2023. The company is on course for mid-year initiation of IMPACT, its Phase 2b biopsy trial of pemvidutide in subjects with NASH.
- Initiation of the IMPACT Phase 2b trial of pemvidutide in NASH expected mid-2023.
- Top-line 48-week results from the MOMENTUM Phase 2 obesity trial expected Q4 2023.
- Top-line results from the Phase 2 trial of HepTcell in chronic hepatitis B (CHB) expected Q1 2024.
- Positive interim data readout from 24-week MOMENTUM Phase 2 obesity trial in March 2023 showed mean weight loss of 10.7% and 9.4% at the 2.4 mg and 1.8 mg doses, respectively, at Week 24, compared to mean weight loss of 1.0% in the placebo group.
Headline financials
Revenue & EPS history
Altimmune · Revenue · Quarterly
$21K
Forward guidance
The company anticipates several key milestones for its clinical assets, including data readouts for the Phase 2 trials of HepTcell in CHB and pemvidutide in obesity, as well as the initiation and data readout of the Phase 2b IMPACT trial of pemvidutide in NASH.
Tailwinds
- Mid-year initiation of IMPACT Phase 2b NASH trial expected.
- Top-line 48-week results from MOMENTUM Phase 2 obesity trial expected Q4 2023.
- Top-line results from Phase 2 trial of HepTcell in CHB expected Q1 2024.
- IMPACT trial has potential to show a statistically significant impact on the key endpoints of NASH resolution and fibrosis improvement.
- Dose reduction will be allowed for subjects who experience GI intolerance in the IMPACT trial.
Headwinds
- Delays in regulatory review.
- Manufacturing and supply chain interruptions.
- Access to clinical sites and enrollment issues.
- Adverse effects on healthcare systems and disruption of the global economy.
- Reliability of the results of studies relating to human safety and possible adverse effects resulting from the administration of the Company’s product candidates.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q1 2023
+2.4%
Avg return
Earnings day
+1.5%
Avg return
5 days after
+5.6%
Avg return
30 days after
60%
21 / 35 earnings
Positive
+35.0%
Q2 2022
Best reaction
-25.1%
Q3 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -2.0% | -8.8% | -15.3% | |
| Q4 2025 | -17.6% | -9.6% | -21.8% | |
| Q3 2025 | +5.1% | +14.1% | +39.7% | |
| Q1 2025 | -4.2% | -7.2% | +19.0% | |
| Q4 2024 | +8.1% | +0.3% | -10.4% | |
| Q3 2024 | +29.5% | +3.5% | +16.9% | |
| Q2 2024 | +12.2% | +14.7% | +12.7% | |
| Q1 2024 | +0.8% | +9.2% | -9.8% | |
| Q4 2023 | +17.7% | +18.3% | -16.1% | |
| Q3 2023 | +1.1% | -6.4% | +146.4% | |
| Q2 2023 | +2.0% | -4.7% | -16.9% | |
| Q1 2023 | +2.2% | -6.6% | -19.7% | |
| Q4 2022 | +1.9% | -2.0% | -64.3% | |
| Q3 2022 | +10.3% | +12.7% | +4.2% | |
| Q2 2022 | +35.0% | +37.3% | +55.4% | |
| Q1 2022 | +31.0% | +34.3% | +117.0% | |
| Q4 2021 | +2.2% | +12.1% | -18.7% | |
| Q3 2021 | -0.5% | +1.3% | -12.3% | |
| Q2 2021 | +6.6% | +14.9% | +56.8% | |
| Q1 2021 | +5.2% | +4.7% | +23.0% | |
| Q4 2020 | -18.6% | -19.5% | -29.3% | |
| Q3 2020 | -25.1% | -18.6% | -1.1% | |
| Q2 2020 | -13.5% | -5.5% | -54.3% | |
| Q1 2020 | +21.4% | +21.6% | +103.8% | |
| Q4 2019 | -7.1% | -6.5% | -2.8% | |
| Q3 2019 | -8.0% | -10.9% | -1.7% | |
| Q2 2019 | -6.5% | -6.5% | -0.9% | |
| Q1 2019 | +2.7% | -4.7% | -3.5% | |
| Q4 2018 | +3.4% | +6.6% | -0.7% | |
| Q3 2018 | -6.8% | -9.1% | -31.5% | |
| Q2 2018 | +4.9% | +0.3% | -21.0% | |
| Q1 2018 | +10.8% | -1.9% | +1.7% | |
| Q4 2017 | -8.3% | -5.9% | -36.0% | |
| Q3 2017 | -1.0% | -7.1% | -25.1% | |
| Q2 2017 | -10.3% | -12.0% | +11.6% | |
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