NASDAQ$ALT

Altimmune Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

Altimmune reported its Q4 2024 financial results and provided a business update.

Altimmune reported a net loss of $23.2 million for the fourth quarter of 2024, with cash, cash equivalents, and short-term investments totaling $131.9 million as of December 31, 2024. The company is advancing pemvidutide in multiple indications and expects to report top-line data from the Phase 2b IMPACT trial in Q2 2025.

  • IMPACT Phase 2b trial of pemvidutide in MASH is on track to report top-line data in Q2 2025.
  • IND applications for pemvidutide in two additional indications have been cleared by the FDA, with Phase 2 trials expected to commence mid-2025.
  • Altimmune will hold a virtual R&D Day on March 13, 2025, to discuss pemvidutide development in obesity, MASH, and additional indications.
  • The company's Board of Directors was strengthened with the addition of two pharmaceutical industry veterans.

Headline financials

Total Revenue

$5K

Previous: $37K-86.5%
EPS (adj)

-$0.33

Previous: -$0.33+0.0%
Capital Expenditures

$0.00

No prior period
Free Cash Flow

-$18.3M

No prior period
Net Income

-$23.2M

Previous: -$31.6M+26.7%
Operating Income

-$24.9M

Previous: -$33.6M+26.0%
Gross Profit

-$28K

Previous: -$1.85M+98.5%
R&D Expense

$19.8M

Previous: $16.9M+17.0%

Revenue & EPS history

Altimmune · Revenue · Quarterly

$5K

Q4 2024-86.5%vs Q4 2023
Beat estimate in 9 of 12 quarters(75%)
ActualEstimate

Forward guidance

Altimmune is focused on advancing pemvidutide in multiple indications. Top-line data from the Phase 2b IMPACT trial in MASH is expected in Q2 2025, and Phase 2 trials in two additional indications are planned to commence mid-2025.

Tailwinds

  • Top-line data from Phase 2b IMPACT trial of pemvidutide in MASH to be reported in Q2 2025.
  • IND applications in two additional indications have received FDA clearance, with Phase 2 trials to commence mid-2025.
  • Company to hold virtual R&D Day on March 13, 2025.
  • Pemvidutide has the potential to achieve statistically significant improvements in biopsy endpoints.
  • FDA Fast Track designation granted to pemvidutide for the treatment of MASH.

Headwinds

  • Forward-looking statements are subject to numerous assumptions, risks, and uncertainties.
  • Delays in regulatory review could impact timelines.
  • Manufacturing and supply chain interruptions may occur.
  • Access to clinical sites and enrollment could face challenges.
  • Adverse effects on healthcare systems and disruption of the global economy could affect results.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+2.4%

Avg return

Earnings day

+1.5%

Avg return

5 days after

+5.6%

Avg return

30 days after

60%

21 / 35 earnings

Positive

+35.0%

Q2 2022

Best reaction

-25.1%

Q3 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.0%-8.8%-15.3%
Q4 2025-17.6%-9.6%-21.8%
Q3 2025+5.1%+14.1%+39.7%
Q1 2025-4.2%-7.2%+19.0%
Q4 2024+8.1%+0.3%-10.4%
Q3 2024+29.5%+3.5%+16.9%
Q2 2024+12.2%+14.7%+12.7%
Q1 2024+0.8%+9.2%-9.8%
Q4 2023+17.7%+18.3%-16.1%
Q3 2023+1.1%-6.4%+146.4%
Q2 2023+2.0%-4.7%-16.9%
Q1 2023+2.2%-6.6%-19.7%
Q4 2022+1.9%-2.0%-64.3%
Q3 2022+10.3%+12.7%+4.2%
Q2 2022+35.0%+37.3%+55.4%
Q1 2022+31.0%+34.3%+117.0%
Q4 2021+2.2%+12.1%-18.7%
Q3 2021-0.5%+1.3%-12.3%
Q2 2021+6.6%+14.9%+56.8%
Q1 2021+5.2%+4.7%+23.0%
Q4 2020-18.6%-19.5%-29.3%
Q3 2020-25.1%-18.6%-1.1%
Q2 2020-13.5%-5.5%-54.3%
Q1 2020+21.4%+21.6%+103.8%
Q4 2019-7.1%-6.5%-2.8%
Q3 2019-8.0%-10.9%-1.7%
Q2 2019-6.5%-6.5%-0.9%
Q1 2019+2.7%-4.7%-3.5%
Q4 2018+3.4%+6.6%-0.7%
Q3 2018-6.8%-9.1%-31.5%
Q2 2018+4.9%+0.3%-21.0%
Q1 2018+10.8%-1.9%+1.7%
Q4 2017-8.3%-5.9%-36.0%
Q3 2017-1.0%-7.1%-25.1%
Q2 2017-10.3%-12.0%+11.6%
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2012
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q3 2012
Q2 2012
Q1 2011
Q1 2012
Q4 2011
Q3 2011
Q2 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

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