NASDAQ$ALT

Altimmune Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

Altimmune reported its Q4 2024 financial results and provided a business update.

Altimmune reported a net loss of $23.2 million for the fourth quarter of 2024, with cash, cash equivalents, and short-term investments totaling $131.9 million as of December 31, 2024. The company is advancing pemvidutide in multiple indications and expects to report top-line data from the Phase 2b IMPACT trial in Q2 2025.

  • IMPACT Phase 2b trial of pemvidutide in MASH is on track to report top-line data in Q2 2025.
  • IND applications for pemvidutide in two additional indications have been cleared by the FDA, with Phase 2 trials expected to commence mid-2025.
  • Altimmune will hold a virtual R&D Day on March 13, 2025, to discuss pemvidutide development in obesity, MASH, and additional indications.
  • The company's Board of Directors was strengthened with the addition of two pharmaceutical industry veterans.

Headline financials

Total Revenue

$5K

Previous: $37K-86.5%
EPS (adj)

-$0.33

Previous: -$0.33+0.0%
Capital Expenditures

$0.00

No prior period
Free Cash Flow

-$18.3M

No prior period
Net Income

-$23.2M

Previous: -$31.6M+26.7%
Operating Income

-$24.9M

Previous: -$33.6M+26.0%
Gross Profit

-$28K

Previous: -$1.85M+98.5%
R&D Expense

$19.8M

Previous: $16.9M+17.0%

Revenue & EPS history

Altimmune · Revenue · Quarterly

$5K

Q4 2024-86.5%vs Q4 2023
Beat estimate in 10 of 13 quarters(77%)
ActualEstimate

Forward guidance

Altimmune is focused on advancing pemvidutide in multiple indications. Top-line data from the Phase 2b IMPACT trial in MASH is expected in Q2 2025, and Phase 2 trials in two additional indications are planned to commence mid-2025.

Tailwinds

  • Top-line data from Phase 2b IMPACT trial of pemvidutide in MASH to be reported in Q2 2025.
  • IND applications in two additional indications have received FDA clearance, with Phase 2 trials to commence mid-2025.
  • Company to hold virtual R&D Day on March 13, 2025.
  • Pemvidutide has the potential to achieve statistically significant improvements in biopsy endpoints.
  • FDA Fast Track designation granted to pemvidutide for the treatment of MASH.

Headwinds

  • Forward-looking statements are subject to numerous assumptions, risks, and uncertainties.
  • Delays in regulatory review could impact timelines.
  • Manufacturing and supply chain interruptions may occur.
  • Access to clinical sites and enrollment could face challenges.
  • Adverse effects on healthcare systems and disruption of the global economy could affect results.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+2.4%

Avg return

Earnings day

+1.5%

Avg return

5 days after

+5.6%

Avg return

30 days after

60%

21 / 35 earnings

Positive

+35.0%

Q2 2022

Best reaction

-25.1%

Q3 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025———
Q1 2026-2.0%-8.8%-15.3%
Q4 2025-17.6%-9.6%-21.8%
Q3 2025+5.1%+14.1%+39.7%
Q1 2025-4.2%-7.2%+19.0%
Q4 2024+8.1%+0.3%-10.4%
Q3 2024+29.5%+3.5%+16.9%
Q2 2024+12.2%+14.7%+12.7%
Q1 2024+0.8%+9.2%-9.8%
Q4 2023+17.7%+18.3%-16.1%
Q3 2023+1.1%-6.4%+146.4%
Q2 2023+2.0%-4.7%-16.9%
Q1 2023+2.2%-6.6%-19.7%
Q4 2022+1.9%-2.0%-64.3%
Q3 2022+10.3%+12.7%+4.2%
Q2 2022+35.0%+37.3%+55.4%
Q1 2022+31.0%+34.3%+117.0%
Q4 2021+2.2%+12.1%-18.7%
Q3 2021-0.5%+1.3%-12.3%
Q2 2021+6.6%+14.9%+56.8%
Q1 2021+5.2%+4.7%+23.0%
Q4 2020-18.6%-19.5%-29.3%
Q3 2020-25.1%-18.6%-1.1%
Q2 2020-13.5%-5.5%-54.3%
Q1 2020+21.4%+21.6%+103.8%
Q4 2019-7.1%-6.5%-2.8%
Q3 2019-8.0%-10.9%-1.7%
Q2 2019-6.5%-6.5%-0.9%
Q1 2019+2.7%-4.7%-3.5%
Q4 2018+3.4%+6.6%-0.7%
Q3 2018-6.8%-9.1%-31.5%
Q2 2018+4.9%+0.3%-21.0%
Q1 2018+10.8%-1.9%+1.7%
Q4 2017-8.3%-5.9%-36.0%
Q3 2017-1.0%-7.1%-25.1%
Q2 2017-10.3%-12.0%+11.6%
Q1 2017———
Q4 2016———
Q3 2016———
Q2 2016———
Q1 2016———
Q4 2015———
Q3 2015———
Q2 2015———
Q1 2015———
Q4 2014———
Q3 2014———
Q2 2014———
Q1 2014———
Q4 2012———
Q4 2013———
Q3 2013———
Q2 2013———
Q1 2013———
Q3 2012———
Q2 2012———
Q1 2011———
Q1 2012———
Q4 2011———
Q3 2011———
Q2 2011———
Q4 2010———
Q3 2010———
Q2 2010———
Q1 2010———

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