NASDAQ$AGIO

Agios Pharmaceuticals Inc · Q3 2020 earnings

Q3 2020 earnings · · Investor relations

Briefing

Agios reported third quarter results with TIBSOVO® net revenue of $31.7 million and narrowed 2020 TIBSOVO® net U.S. revenue guidance to $113–115 million.

Agios Pharmaceuticals reported total revenue of $34.7 million for the third quarter of 2020, which includes $31.7 million of net product revenue from sales of TIBSOVO®, $2.3 million in collaboration revenue and $0.7 million in royalty revenue. Net loss was $99.0 million for the third quarter of 2020.

  • TIBSOVO® net sales of $31.7 million, an increase of 15% from the second quarter of 2020.
  • Reported topline mature overall survival results from ClarIDHy Phase 3 study of TIBSOVO® in previously treated IDH1-mutant cholangiocarcinoma patients.
  • Withdrew European Marketing Authorization Application (MAA) for TIBSOVO® in IDH1-mutant relapsed or refractory acute myeloid leukemia (AML).
  • Initiated Phase 1 healthy volunteers study of AG-946, a next-generation, orally available, small molecule activator of the metabolic enzyme pyruvate kinase-R (PKR).

Headline financials

Total Revenue

$34.7M

Previous: $26M+33.4%
EPS (adj)

-$1.43

Previous: -$1.81+21.0%
Capital Expenditures

-$13.9M

Previous: -$5.35M-159.8%
Free Cash Flow

-$113M

Previous: -$112M-1.2%
Net Income

-$99M

Previous: -$106M+6.8%
Operating Income

-$90.3M

Previous: -$109M+17.2%
Gross Profit

$34.1M

Previous: $25.6M+32.9%
Cash & Equivalents

$105M

No prior period
Total Assets

$908M

No prior period
Stock-Based Comp

$18.4M

No prior period

Revenue & EPS history

Agios · Revenue · Quarterly

$34.7M

Q3 2020+33.4%vs Q3 2019
Beat estimate in 7 of 15 quarters(47%)
ActualEstimate

Forward guidance

Agios expects to deliver full-year 2020 U.S. revenue for TIBSOVO® of $113-115 million.

Tailwinds

  • Report topline data from ACTIVATE trial by the end of 2020.
  • Report topline data from ACTIVATE-T trial in Q1 2021.
  • Finalize pivotal development plan for mitapivat in thalassemia by the end of 2020.
  • Finalize pivotal development plan for mitapivat in sickle cell disease in the first half of 2021.
  • Submit a supplemental new drug application for TIBSOVO® in previously treated cholangiocarcinoma in Q1 2021.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2020

Historical avgQ3 2020

-0.0%

Avg return

Earnings day

+0.5%

Avg return

5 days after

+1.9%

Avg return

30 days after

50%

25 / 50 earnings

Positive

+19.2%

Q2 2022

Best reaction

-15.0%

Q1 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.1%+11.1%+18.5%
Q4 2025+1.3%+0.4%+0.5%
Q3 2025+2.8%-4.7%-30.4%
Q1 2025+4.2%-4.6%+8.1%
Q4 2024+1.5%+2.4%-5.7%
Q3 2024-3.1%+0.9%+28.3%
Q2 2024-5.3%-8.2%-1.1%
Q1 2024+2.6%-2.6%+8.0%
Q4 2023+2.4%+4.6%+15.6%
Q3 2023+5.6%+9.1%+7.5%
Q2 2023-2.0%+0.1%+8.4%
Q1 2023+11.7%+11.1%+13.9%
Q4 2022-5.3%-4.6%-18.0%
Q3 2022-6.9%-2.0%+13.3%
Q2 2022+19.2%+9.7%+27.7%
Q1 2022-6.3%-9.7%-18.5%
Q4 2021+11.8%+16.9%+4.5%
Q3 2021-7.3%-9.1%-31.3%
Q2 2021-3.8%-5.8%-9.9%
Q1 2021+0.7%-3.4%+0.6%
Q4 2020-10.3%-7.5%-6.1%
Q3 2020-5.5%+0.2%+7.7%
Q2 2020-8.3%-10.7%-18.9%
Q1 2020-15.0%-9.4%+18.8%
Q4 2019+4.3%+7.9%-24.9%
Q3 2019+6.4%+9.2%+23.0%
Q2 2019-12.6%-15.5%-21.1%
Q1 2019+3.2%-5.1%-13.2%
Q4 2018+9.7%+6.8%+20.3%
Q3 2018+11.6%+13.1%+4.3%
Q2 2018-9.0%-7.3%-6.9%
Q1 2018-0.9%+1.1%+17.5%
Q4 2017+3.0%+1.5%+8.4%
Q3 2017+0.0%+3.6%-4.8%
Q2 2017-0.8%-3.6%+4.5%
Q1 2017+6.8%+7.5%+5.1%
Q4 2016+17.3%+9.3%+16.3%
Q3 2016+7.3%+17.2%+23.6%
Q2 2016-6.3%-11.0%-21.0%
Q1 2016-7.2%
Q4 2015-8.3%
Q3 2015-2.6%
Q2 2015-12.4%
Q1 2015+13.3%
Q4 2014-7.3%
Q3 2014-1.6%
Q2 2014+1.4%
Q1 2014-10.3%
Q3 2013+3.2%
Q2 2013+6.4%
Q4 2013
Q3 2012
Q2 2012
Q1 2012

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