NASDAQ$AGIO

Agios Pharmaceuticals Inc · Q2 2024 earnings

Q2 2024 earnings · · Investor relations

Briefing

Agios reported second quarter 2024 financial results and business highlights.

Agios Pharmaceuticals reported PYRUKYND® net revenue of $8.6 million in Q2 2024 and announced a $905 million purchase agreement for vorasidenib royalty with Royalty Pharma. The company's cash, cash equivalents and marketable securities totaled $645.3 million as of June 30, 2024. They also reported positive topline data from Phase 3 ENERGIZE-T Study and expect to file sNDA based on ENERGIZE and ENERGIZE-T Studies by the end of 2024.

  • PYRUKYND® net revenue reached $8.6 million, a 5% sequential increase from Q1 2024.
  • A total of 201 unique patients have completed prescription enrollment forms for PYRUKYND®, representing a 7% increase over the first quarter of 2024.
  • Agios announced a $905 million purchase agreement with Royalty Pharma for vorasidenib royalty.
  • Topline data was reported in the Phase 3 ACTIVATE-KidsT study of mitapivat in children with PK deficiency.

Headline financials

Total Revenue

$8.62M

Previous: $6.71M+28.4%
EPS

-$1.69

Previous: -$1.51-11.9%
Capital Expenditures

-$299K

Previous: -$396K+24.5%
Free Cash Flow

-$96.4M

Previous: -$84.2M-14.5%
Net Income

-$96.1M

Previous: -$83.8M-14.7%
Operating Income

-$106M

Previous: -$93.7M-12.9%
Gross Profit

$7.12M

Previous: $5.6M+27.1%
R&D Expense

$75.8M

No prior period
Stock-Based Comp

$11.6M

Previous: $11.7M-1.5%

Revenue & EPS history

Agios · Revenue · Quarterly

$8.62M

Q2 2024+28.4%vs Q2 2023
Beat estimate in 6 of 12 quarters(50%)
ActualEstimate

Forward guidance

Agios expects to execute on key milestones and priorities by the end of 2024.

Tailwinds

  • File sNDA for mitapivat in thalassemia based on the positive results from the Phase 3 ENERGIZE and ENERGIZE-T trials (year-end).
  • Complete enrollment in the Phase 3 portion of the RISE UP study of mitapivat (year-end).
  • Dose first patient in Phase 2b study of tebapivat (AG-946) (mid-year).
  • Potential approval of Servier’s vorasidenib for the treatment of IDH-mutant diffuse glioma.
  • The FDA has assigned a PDUFA action date of August 20, 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2024

Historical avgQ2 2024

-0.0%

Avg return

Earnings day

+0.5%

Avg return

5 days after

+1.9%

Avg return

30 days after

50%

25 / 50 earnings

Positive

+19.2%

Q2 2022

Best reaction

-15.0%

Q1 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.1%+11.1%+18.5%
Q4 2025+1.3%+0.4%+0.5%
Q3 2025+2.8%-4.7%-30.4%
Q1 2025+4.2%-4.6%+8.1%
Q4 2024+1.5%+2.4%-5.7%
Q3 2024-3.1%+0.9%+28.3%
Q2 2024-5.3%-8.2%-1.1%
Q1 2024+2.6%-2.6%+8.0%
Q4 2023+2.4%+4.6%+15.6%
Q3 2023+5.6%+9.1%+7.5%
Q2 2023-2.0%+0.1%+8.4%
Q1 2023+11.7%+11.1%+13.9%
Q4 2022-5.3%-4.6%-18.0%
Q3 2022-6.9%-2.0%+13.3%
Q2 2022+19.2%+9.7%+27.7%
Q1 2022-6.3%-9.7%-18.5%
Q4 2021+11.8%+16.9%+4.5%
Q3 2021-7.3%-9.1%-31.3%
Q2 2021-3.8%-5.8%-9.9%
Q1 2021+0.7%-3.4%+0.6%
Q4 2020-10.3%-7.5%-6.1%
Q3 2020-5.5%+0.2%+7.7%
Q2 2020-8.3%-10.7%-18.9%
Q1 2020-15.0%-9.4%+18.8%
Q4 2019+4.3%+7.9%-24.9%
Q3 2019+6.4%+9.2%+23.0%
Q2 2019-12.6%-15.5%-21.1%
Q1 2019+3.2%-5.1%-13.2%
Q4 2018+9.7%+6.8%+20.3%
Q3 2018+11.6%+13.1%+4.3%
Q2 2018-9.0%-7.3%-6.9%
Q1 2018-0.9%+1.1%+17.5%
Q4 2017+3.0%+1.5%+8.4%
Q3 2017+0.0%+3.6%-4.8%
Q2 2017-0.8%-3.6%+4.5%
Q1 2017+6.8%+7.5%+5.1%
Q4 2016+17.3%+9.3%+16.3%
Q3 2016+7.3%+17.2%+23.6%
Q2 2016-6.3%-11.0%-21.0%
Q1 2016-7.2%
Q4 2015-8.3%
Q3 2015-2.6%
Q2 2015-12.4%
Q1 2015+13.3%
Q4 2014-7.3%
Q3 2014-1.6%
Q2 2014+1.4%
Q1 2014-10.3%
Q3 2013+3.2%
Q2 2013+6.4%
Q4 2013
Q3 2012
Q2 2012
Q1 2012

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