NYSE$LLY

Eli Lilly & Co · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Eli Lilly reported Q1 2025 revenue of $12.73B with net income of $2.76B and diluted EPS of $3.06.

Revenue surged 45% to $12.73 billion, led by Mounjaro and Zepbound growth and strong legacy diabetes and oncology franchises. Net income rose 23% to $2.76 billion; diluted EPS was $3.06 versus $2.48 a year ago. Acquired IPR&D charges of $1.57 billion partially offset higher gross margin.

  • Q1 revenue $12.73B (+45% YoY).
  • Net income $2.76B; diluted EPS $3.06.
  • Incretin portfolio driving volume and price/mix.
  • IPR&D charge $1.57B from business development.
  • Manufacturing capacity expansion for GLP-1 supply.

Headline financials

Total Revenue

$12.7B

Previous: $8.77B+45.2%
EPS (adj)

$3.06

Previous: $2.48+23.4%
Volume change

53.0%

No prior period
Price change

-6.0%

No prior period
Gross margin

82.5%

No prior period
Capital Expenditures

-$1.51B

Previous: -$986M-53.0%
Net Income

$2.76B

Previous: $2.24B+23.0%
Operating Income

$3.7B

Previous: $2.51B+47.3%
Gross Profit

$10.5B

Previous: $7.09B+48.1%
R&D Expense

$2.73B

Previous: $2.52B+8.4%

Revenue & EPS history

Eli Lilly · Revenue · Quarterly

$12.7B

Q1 2025+45.2%vs Q1 2024
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

Eli Lilly · $2.45B total across 2 segments · Q3 2023

  • Mounjaro
    $1.41B+652.4%
  • Verzenio
    $1.04B+68.4%

Forward guidance

Lilly raised 2025 revenue and EPS guidance on the Q1 call, citing incretin demand and manufacturing ramp; the 10-Q notes ongoing capacity investments and pipeline readouts.

Tailwinds

  • Mounjaro/Zepbound demand exceeding supply ramp.
  • Pipeline catalysts in Alzheimer's, oncology, and obesity.
  • Gross margin expansion on mix.

Headwinds

  • IPR&D and integration costs from acquisitions.
  • Competitive GLP-1 supply and pricing dynamics.
  • Patent and IRA pricing policy overhang.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.1%

Avg return

Earnings day

+0.8%

Avg return

5 days after

+3.1%

Avg return

30 days after

43%

29 / 67 earnings

Positive

+15.9%

Q2 2023

Best reaction

-14.1%

Q2 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.1%+16.2%+29.9%
Q4 2025+10.3%+4.1%-1.3%
Q3 2025+3.2%+11.5%+32.2%
Q2 2025-14.1%-14.3%-2.6%
Q1 2025-11.7%-13.8%-17.9%
Q4 2024+3.3%+2.7%+3.3%
Q3 2024-8.2%-10.8%-12.0%
Q2 2024+15.5%+17.6%+16.9%
Q1 2024+5.4%-0.3%+10.6%
Q4 2023+2.7%+4.8%+10.5%
Q3 2023+2.4%+8.2%+5.3%
Q2 2023+15.9%+16.3%+26.2%
Q1 2023+5.2%+7.4%+13.2%
Q4 2022-1.0%-0.8%-7.0%
Q3 2022-2.0%-1.3%+2.3%
Q2 2022-4.0%-3.4%-4.0%
Q1 2022+2.5%+1.0%+13.5%
Q4 2021-3.4%-4.4%+4.8%
Q3 2021+2.1%+4.0%+6.9%
Q2 2021+6.4%+6.8%+5.3%
Q1 2021-3.6%-2.4%+6.4%
Q4 2020-3.3%-6.3%-2.5%
Q3 2020-7.3%-7.9%+2.2%
Q2 2020-7.1%-4.3%-8.9%
Q1 2020+4.0%+0.4%-3.5%
Q4 2019-0.2%+2.5%-9.9%
Q3 2019-1.8%+2.9%+5.8%
Q2 2019+0.2%+3.4%+3.2%
Q1 2019-1.2%-2.2%-3.1%
Q4 2018-2.4%-2.0%+5.2%
Q3 2018-0.4%+1.9%+5.2%
Q2 2018+8.5%+8.7%+17.9%
Q1 2018+1.2%+3.2%+3.1%
Q4 2017-4.3%-10.0%-10.3%
Q3 2017-2.7%-3.8%-4.0%
Q2 2017-3.4%-1.9%-6.9%
Q1 2017-2.9%-1.6%-6.1%
Q4 2016+3.9%+3.4%+11.0%
Q3 2016-1.0%-3.9%-12.3%
Q2 2016+1.7%+1.1%-4.8%
Q1 2016-1.8%
Q4 2015-3.3%
Q3 2015+1.7%
Q2 2015-1.9%
Q1 2015-1.0%
Q4 2014-0.6%
Q3 2014+2.1%
Q2 2014-0.7%
Q1 2014-1.8%
Q4 2013+0.2%
Q3 2013+0.8%
Q2 2013+3.1%
Q1 2013-3.3%
Q4 2012+2.9%
Q3 2012-1.6%
Q2 2012+3.9%
Q1 2012+2.3%
Q4 2011+1.0%
Q3 2011-1.9%
Q2 2011-0.1%
Q1 2011-0.1%
Q4 2010-1.6%
Q3 2010-0.3%
Q2 2010+2.5%
Q1 2010+0.4%
Q4 2009-0.8%
Q4 2008-0.3%

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