NASDAQ$XENE

Xenon Pharmaceuticals Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Xenon Pharmaceuticals reported financial results for the third quarter of 2022 and provided a corporate update.

Xenon Pharmaceuticals reported a net loss of $37.2 million for the third quarter of 2022, compared to a net loss of $15.4 million for the same period in 2021. The company's cash and cash equivalents and marketable securities were $752.2 million as of September 30, 2022, providing a cash runway into 2026.

  • XEN1101 Phase 3 program launched with initiation of X-TOLE2 clinical trial.
  • Strong financial position of approximately $752 million to fully support XEN1101 Phase 3 program development and expected cash runway into 2026.
  • XEN1101 represents the most advanced potassium channel modulator in clinical development.
  • Topline data from the XEN1101 MDD study is expected in the third quarter of 2023.

Headline financials

Total Revenue

$132K

Previous: $8.12M-98.4%
EPS (adj)

-$0.57

Previous: -$0.36-58.3%
Capital Expenditures

-$1.14M

Previous: -$1.54M+25.7%
Free Cash Flow

-$38.3M

Previous: -$17M-125.5%
Net Income

-$37.2M

Previous: -$15.4M-140.5%
Operating Income

-$38.1M

Previous: -$15.6M-144.4%
Gross Profit

-$29.3M

Previous: $2.43M-1306.7%
Cash & Equivalents

$638M

Previous: $87.8M+626.8%
Total Assets

$776M

Previous: $264M+193.5%
Stock-Based Comp

$5.74M

Previous: $2.64M+117.3%

Revenue & EPS history

Xenon Pharmaceuticals · Revenue · Quarterly

$132K

Q3 2022-98.4%vs Q3 2021
Beat estimate in 3 of 11 quarters(27%)
ActualEstimate

Forward guidance

Xenon anticipates having sufficient cash to fund operations into 2026, excluding any revenue generated from existing partnerships or potential new partnering arrangements. Topline results from the X-NOVA study are anticipated in the third quarter of 2023.

Tailwinds

  • Sufficient cash to fund operations into 2026.
  • Advancing a novel product pipeline of neurology therapies.
  • Focus on epilepsy with XEN1101.
  • Initiated XEN1101 Phase 3 development program.
  • Partnered programs with Neurocrine Biosciences.

Headwinds

  • Clinical trials may not demonstrate safety and efficacy.
  • Assumptions regarding planned expenditures and sufficiency of cash may be incorrect.
  • Product candidates may fail in development or not receive regulatory approvals.
  • Regulatory agencies may impose additional requirements or delay the initiation of clinical trials.
  • Impact of the ongoing COVID-19 pandemic on research and clinical development plans.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

-1.2%

Avg return

Earnings day

-1.4%

Avg return

5 days after

+0.8%

Avg return

30 days after

39%

19 / 49 earnings

Positive

+15.8%

Q2 2018

Best reaction

-17.5%

Q3 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.5%-6.1%-11.8%
Q4 2025-3.7%-4.2%+21.3%
Q3 2025-4.9%-7.0%+8.5%
Q2 2025+5.5%+12.1%+9.1%
Q1 2025+2.3%+0.7%+5.7%
Q4 2024-3.4%-3.0%-10.6%
Q3 2024-4.8%-9.6%-10.5%
Q1 2024-5.6%-5.5%-12.2%
Q4 2023-2.1%-3.8%-10.0%
Q3 2023-5.6%-6.6%+20.6%
Q2 2023+8.6%+6.2%+7.9%
Q1 2023-3.2%-5.5%+0.0%
Q4 2022-5.3%-5.9%-9.3%
Q3 2022-4.9%-1.0%+5.1%
Q2 2022+0.1%-4.4%-3.3%
Q1 2022+5.9%+17.1%+16.7%
Q4 2021+3.3%-4.6%-3.6%
Q3 2021-10.1%-10.1%-26.7%
Q2 2021+6.3%+5.6%+3.9%
Q1 2021-4.0%-4.5%+4.6%
Q4 2020+8.2%+6.6%-4.2%
Q3 2020-2.3%+1.1%-0.4%
Q2 2020-2.1%-3.6%-1.9%
Q1 2020+4.3%-3.6%-9.4%
Q4 2019-9.3%-18.7%-10.3%
Q3 2019+0.9%-0.2%+53.9%
Q2 2019+0.6%+4.0%+10.2%
Q1 2019-4.6%-6.6%+8.7%
Q4 2018+7.3%+6.3%+18.8%
Q3 2018-5.7%-9.7%-29.4%
Q2 2018+15.8%+23.7%+38.4%
Q1 2018+0.0%-1.7%+5.0%
Q4 2017+6.2%+17.3%+22.2%
Q3 2017-17.5%-22.2%-25.4%
Q2 2017-4.8%-7.9%+1.6%
Q1 2017-2.4%-1.2%-7.1%
Q4 2016+0.0%+0.0%-54.2%
Q3 2016-2.5%-1.3%-0.6%
Q2 2016+1.5%+3.6%+9.6%
Q1 2016+0.7%
Q4 2015-1.1%
Q3 2015-1.7%
Q2 2015-6.0%
Q1 2015+0.7%
Q4 2012+6.1%
Q3 2014+6.1%
Q4 2014-5.5%
Q3 2013-9.7%
Q4 2013-9.7%
Q1 2014
Q2 2013
Q1 2013
Q3 2012

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