NASDAQ$XENE
Xenon Pharmaceuticals Inc · Q1 2026 earnings
Q1 2026 earnings · · Investor relations
Briefing
Xenon Pharmaceuticals reported Q1 2026 collaboration revenue of $0 and a net loss of $102.3M ($1.17 per share).
Xenon Pharmaceuticals reported no collaboration revenue in Q1 2026 versus $7.5 million a year ago when a Neurocrine milestone was recognized. Net loss was $102.3 million, or $1.17 per share, versus $65.0 million as R&D rose to $88.5 million on advancing epilepsy and neurology programs.
- Collaboration revenue $0 vs $7.5M milestone prior year.
- Net loss $102.3M; R&D $88.5M (+45% YoY).
- XEN1101 and partnered Nav1 programs in clinic.
- Cash runway and partnership economics critical.
- No product revenue yet.
Headline financials
Revenue & EPS history
Xenon Pharmaceuticals · Revenue · Quarterly
$0
Forward guidance
Clinical-stage outlook driven by trial milestones and Neurocrine collaboration; no product revenue guidance.
Tailwinds
- Robust pipeline in ion-channel neurology.
- Partnership with Neurocrine on key assets.
- Strong cash balance relative to burn.
Headwinds
- Higher loss on stepped-up R&D.
- Milestone timing lumpiness.
- Trial and regulatory risk.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2026
-1.2%
Avg return
Earnings day
-1.4%
Avg return
5 days after
+0.8%
Avg return
30 days after
39%
19 / 49 earnings
Positive
+15.8%
Q2 2018
Best reaction
-17.5%
Q3 2017
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -4.5% | -6.1% | -11.8% | |
| Q4 2025 | -3.7% | -4.2% | +21.3% | |
| Q3 2025 | -4.9% | -7.0% | +8.5% | |
| Q2 2025 | +5.5% | +12.1% | +9.1% | |
| Q1 2025 | +2.3% | +0.7% | +5.7% | |
| Q4 2024 | -3.4% | -3.0% | -10.6% | |
| Q3 2024 | -4.8% | -9.6% | -10.5% | |
| Q1 2024 | -5.6% | -5.5% | -12.2% | |
| Q4 2023 | -2.1% | -3.8% | -10.0% | |
| Q3 2023 | -5.6% | -6.6% | +20.6% | |
| Q2 2023 | +8.6% | +6.2% | +7.9% | |
| Q1 2023 | -3.2% | -5.5% | +0.0% | |
| Q4 2022 | -5.3% | -5.9% | -9.3% | |
| Q3 2022 | -4.9% | -1.0% | +5.1% | |
| Q2 2022 | +0.1% | -4.4% | -3.3% | |
| Q1 2022 | +5.9% | +17.1% | +16.7% | |
| Q4 2021 | +3.3% | -4.6% | -3.6% | |
| Q3 2021 | -10.1% | -10.1% | -26.7% | |
| Q2 2021 | +6.3% | +5.6% | +3.9% | |
| Q1 2021 | -4.0% | -4.5% | +4.6% | |
| Q4 2020 | +8.2% | +6.6% | -4.2% | |
| Q3 2020 | -2.3% | +1.1% | -0.4% | |
| Q2 2020 | -2.1% | -3.6% | -1.9% | |
| Q1 2020 | +4.3% | -3.6% | -9.4% | |
| Q4 2019 | -9.3% | -18.7% | -10.3% | |
| Q3 2019 | +0.9% | -0.2% | +53.9% | |
| Q2 2019 | +0.6% | +4.0% | +10.2% | |
| Q1 2019 | -4.6% | -6.6% | +8.7% | |
| Q4 2018 | +7.3% | +6.3% | +18.8% | |
| Q3 2018 | -5.7% | -9.7% | -29.4% | |
| Q2 2018 | +15.8% | +23.7% | +38.4% | |
| Q1 2018 | +0.0% | -1.7% | +5.0% | |
| Q4 2017 | +6.2% | +17.3% | +22.2% | |
| Q3 2017 | -17.5% | -22.2% | -25.4% | |
| Q2 2017 | -4.8% | -7.9% | +1.6% | |
| Q1 2017 | -2.4% | -1.2% | -7.1% | |
| Q4 2016 | +0.0% | +0.0% | -54.2% | |
| Q3 2016 | -2.5% | -1.3% | -0.6% | |
| Q2 2016 | +1.5% | +3.6% | +9.6% | |
| Q1 2016 | +0.7% | — | — | |
| Q4 2015 | -1.1% | — | — | |
| Q3 2015 | -1.7% | — | — | |
| Q2 2015 | -6.0% | — | — | |
| Q1 2015 | +0.7% | — | — | |
| Q4 2012 | +6.1% | — | — | |
| Q3 2014 | +6.1% | — | — | |
| Q4 2014 | -5.5% | — | — | |
| Q3 2013 | -9.7% | — | — | |
| Q4 2013 | -9.7% | — | — | |
| Q1 2014 | — | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — | |
| Q3 2012 | — | — | — |
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