NASDAQ$XENE

Xenon Pharmaceuticals Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

Xenon Pharmaceuticals reported Q3 2025, net loss of $90.9M.

For Q3 2025, Xenon Pharmaceuticals reported a net loss of $90.9M. Management discusses operations, liquidity, and outlook in the quarterly filing.

  • Net loss $90.9M.
  • Xenon Pharmaceuticals highlights liquidity, operations, and sector risks in MD&A.
  • Xenon Pharmaceuticals highlights liquidity, operations, and sector risks in MD&A.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$1.15

Previous: -$0.81-42.0%
R&D Expenses

$77.1M

Previous: $57M+35.3%
G&A Expenses

$19.3M

Previous: $16.7M+15.4%
Other Income

$6.12M

Previous: $10.6M-42.1%
Income Tax Expense

-$677K

Previous: $320K-311.6%
Unrealized Gain on Securities

$364K

Previous: $3.55M-89.7%
Weighted Avg Shares

79.2M

Previous: 77.9M+1.7%
Capital Expenditures

-$481K

Previous: -$593K+18.9%
Net Income

-$90.9M

Previous: -$62.8M-44.7%
Operating Income

-$96.3M

Previous: -$73.7M-30.8%

Revenue & EPS history

Xenon Pharmaceuticals · Revenue · Quarterly

$0

Q3 2025
Beat estimate in 3 of 11 quarters(27%)
ActualEstimate

Forward guidance

The filing discusses Xenon Pharmaceuticals's outlook, including capital allocation, operating priorities, and market risks relevant to the reported quarter.

Tailwinds

  • Xenon Pharmaceuticals cites operational priorities and demand trends supporting the outlook.
  • Balance sheet and liquidity actions aim to fund growth and returns.

Headwinds

  • GAAP profitability remained under pressure in Q3 2025.
  • Macro, pricing, and input-cost volatility could pressure margins.
  • Segment mix and one-time items may affect quarter-to-quarter comparability.
  • Clinical, regulatory, and R&D spend dominate the near-term outlook.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

-1.2%

Avg return

Earnings day

-1.4%

Avg return

5 days after

+0.8%

Avg return

30 days after

39%

19 / 49 earnings

Positive

+15.8%

Q2 2018

Best reaction

-17.5%

Q3 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.5%-6.1%-11.8%
Q4 2025-3.7%-4.2%+21.3%
Q3 2025-4.9%-7.0%+8.5%
Q2 2025+5.5%+12.1%+9.1%
Q1 2025+2.3%+0.7%+5.7%
Q4 2024-3.4%-3.0%-10.6%
Q3 2024-4.8%-9.6%-10.5%
Q1 2024-5.6%-5.5%-12.2%
Q4 2023-2.1%-3.8%-10.0%
Q3 2023-5.6%-6.6%+20.6%
Q2 2023+8.6%+6.2%+7.9%
Q1 2023-3.2%-5.5%+0.0%
Q4 2022-5.3%-5.9%-9.3%
Q3 2022-4.9%-1.0%+5.1%
Q2 2022+0.1%-4.4%-3.3%
Q1 2022+5.9%+17.1%+16.7%
Q4 2021+3.3%-4.6%-3.6%
Q3 2021-10.1%-10.1%-26.7%
Q2 2021+6.3%+5.6%+3.9%
Q1 2021-4.0%-4.5%+4.6%
Q4 2020+8.2%+6.6%-4.2%
Q3 2020-2.3%+1.1%-0.4%
Q2 2020-2.1%-3.6%-1.9%
Q1 2020+4.3%-3.6%-9.4%
Q4 2019-9.3%-18.7%-10.3%
Q3 2019+0.9%-0.2%+53.9%
Q2 2019+0.6%+4.0%+10.2%
Q1 2019-4.6%-6.6%+8.7%
Q4 2018+7.3%+6.3%+18.8%
Q3 2018-5.7%-9.7%-29.4%
Q2 2018+15.8%+23.7%+38.4%
Q1 2018+0.0%-1.7%+5.0%
Q4 2017+6.2%+17.3%+22.2%
Q3 2017-17.5%-22.2%-25.4%
Q2 2017-4.8%-7.9%+1.6%
Q1 2017-2.4%-1.2%-7.1%
Q4 2016+0.0%+0.0%-54.2%
Q3 2016-2.5%-1.3%-0.6%
Q2 2016+1.5%+3.6%+9.6%
Q1 2016+0.7%
Q4 2015-1.1%
Q3 2015-1.7%
Q2 2015-6.0%
Q1 2015+0.7%
Q4 2012+6.1%
Q3 2014+6.1%
Q4 2014-5.5%
Q3 2013-9.7%
Q4 2013-9.7%
Q1 2014
Q2 2013
Q1 2013
Q3 2012

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