NASDAQ$TYRA

Tyra Biosciences Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results for the quarter ended March 31, 2022, and highlighted recent corporate progress.

Tyra Biosciences reported a net loss of $14.8 million for the first quarter of 2022, with cash and cash equivalents totaling $292.5 million as of March 31, 2022. The company is on track to file INDs for TYRA-300 and TYRA-200 in 2022 and is progressing its pipeline.

  • Net loss for Q1 2022 was $14.8 million, compared to $4.2 million for the same period in 2021.
  • Research and development expense for Q1 2022 was $9.6 million, compared to $3.5 million for the same period in 2021.
  • General and administrative expense for Q1 2022 was $5.2 million, compared to $0.7 million for the same period in 2021.
  • Cash and cash equivalents totaled $292.5 million as of March 31, 2022.

Headline financials

EPS (adj)

-$0.36

Previous: -$0.19-92.3%
Weighted Average Shares Outstanding

41.6M

No prior period
Capital Expenditures

$239K

No prior period
Free Cash Flow

-$9.16M

No prior period
Net Income

-$14.8M

Previous: -$4.21M-252.2%
Operating Income

-$14.8M

Previous: -$4.21M-252.3%
Cash & Equivalents

$292M

No prior period
Total Assets

$299M

No prior period
Stock-Based Comp

$3.97M

No prior period

Revenue & EPS history

Tyra Biosciences · Revenue · Quarterly

$0

Q4 2025

Forward guidance

Tyra Biosciences anticipates submitting INDs for TYRA-300 in mid-2022 and TYRA-200 in the second half of 2022, while continuing to advance its pipeline.

Tailwinds

  • Potential to develop next-generation targeted therapies that improve clinical outcomes.
  • Expected IND submission timing for TYRA-300 and TYRA-200 remains on track.
  • Planned advancement of the development pipeline, including expanding the nomination of clinical candidates from FGFR3-related skeletal dysplasia, RET and FGFR4 programs.
  • Transitioning to a clinical-stage company.
  • Focus on developing purpose-built therapies to overcome tumor resistance and improve outcomes for patients with cancer.

Headwinds

  • Early stage of development efforts with no product candidates tested in clinical trials.
  • Approach to discover and develop drugs based on the SNÅP platform is novel and unproven.
  • Potential delays in the commencement, enrollment, and completion of preclinical studies and clinical trials.
  • Dependence on third parties in connection with manufacturing, research and preclinical testing.
  • Unexpected adverse side effects or inadequate efficacy of product candidates.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+2.0%

Avg return

Earnings day

+3.0%

Avg return

5 days after

-0.8%

Avg return

30 days after

50%

9 / 18 earnings

Positive

+29.8%

Q3 2021

Best reaction

-11.5%

Q4 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+1.5%+7.7%+21.8%
Q3 2025+0.3%+8.4%+50.6%
Q2 2025+0.4%-4.3%+17.0%
Q1 2025-3.1%-4.0%+2.3%
Q4 2024-0.8%-10.5%+3.9%
Q3 2024-5.9%-6.9%-8.1%
Q1 2024-3.8%+3.1%+9.7%
Q4 2023+7.0%+3.0%-9.7%
Q3 2023-6.3%-8.1%+2.5%
Q2 2023+0.9%+1.6%-3.4%
Q1 2023-3.3%+7.0%+13.1%
Q4 2022-3.3%+0.0%-9.8%
Q3 2022-7.1%+12.9%-3.1%
Q2 2022+11.1%+14.7%-24.0%
Q1 2022+0.1%-5.9%-17.8%
Q4 2021-11.5%-5.3%-6.4%
Q2 2021+29.8%+20.3%-26.6%
Q3 2021+29.8%+20.3%-26.6%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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