NASDAQ$TYRA

Tyra Biosciences Inc · Q1 2023 earnings

Q1 2023 earnings · · Investor relations

Briefing

Reported financial results for the quarter ended March 31, 2023 and highlighted recent corporate progress.

Tyra Biosciences reported a net loss of $11.9 million for the first quarter of 2023, with a strong cash position of $241.7 million as of March 31, 2023. The company continued to advance its SURF301 Phase 1/2 clinical study for oncology and expanded the development of TYRA-300 into achondroplasia. The IND for TYRA-200 was cleared, with a Phase 1 study on track for the second half of 2023.

  • SURF301 Phase 1/2 oncology study continued to advance.
  • Expanded TYRA-300 clinical development into achondroplasia.
  • IND for TYRA-200 cleared with Phase 1 study on track for 2H 2023.
  • Maintained a strong cash position of $241.7 million as of Q1 2023.

Headline financials

EPS (adj)

-$0.28

Previous: -$0.36+22.2%
Capital Expenditures

$41K

Previous: $239K-82.8%
Free Cash Flow

-$9.89M

Previous: -$9.16M-7.9%
Net Income

-$11.9M

Previous: -$14.8M+19.9%
Operating Income

-$14.3M

Previous: -$14.8M+3.4%
Cash & Equivalents

$242M

Previous: $292M-17.4%
Total Assets

$255M

Previous: $299M-14.7%
Stock-Based Comp

$2.43M

Previous: $3.97M-38.7%

Revenue & EPS history

Tyra Biosciences · Revenue · Quarterly

$0

Q4 2025

Forward guidance

Tyra Biosciences anticipates continued progress in its clinical programs and advancement of its pipeline.

Tailwinds

  • Advancing SURF301 Phase 1/2 study for oncology.
  • Expanding development of TYRA-300 into achondroplasia.
  • Phase 1 study of TYRA-200 on track for 2H 2023.
  • Continued advancement of in-house precision medicine discovery engine, SNÅP.
  • Cash position expected to support clinical and operational milestones over at least the next two years.

Headwinds

  • Drug discovery and development efforts are early and unproven.
  • Potential delays in commencement, enrollment, and completion of preclinical studies and clinical trials.
  • Unexpected adverse side effects or inadequate efficacy of product candidates.
  • Dependence on third parties for manufacturing, research, and preclinical testing.
  • Unstable market and economic conditions may adversely affect business and financial condition.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2023

Historical avgQ1 2023

+2.0%

Avg return

Earnings day

+3.0%

Avg return

5 days after

-0.8%

Avg return

30 days after

50%

9 / 18 earnings

Positive

+29.8%

Q3 2021

Best reaction

-11.5%

Q4 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+1.5%+7.7%+21.8%
Q3 2025+0.3%+8.4%+50.6%
Q2 2025+0.4%-4.3%+17.0%
Q1 2025-3.1%-4.0%+2.3%
Q4 2024-0.8%-10.5%+3.9%
Q3 2024-5.9%-6.9%-8.1%
Q1 2024-3.8%+3.1%+9.7%
Q4 2023+7.0%+3.0%-9.7%
Q3 2023-6.3%-8.1%+2.5%
Q2 2023+0.9%+1.6%-3.4%
Q1 2023-3.3%+7.0%+13.1%
Q4 2022-3.3%+0.0%-9.8%
Q3 2022-7.1%+12.9%-3.1%
Q2 2022+11.1%+14.7%-24.0%
Q1 2022+0.1%-5.9%-17.8%
Q4 2021-11.5%-5.3%-6.4%
Q2 2021+29.8%+20.3%-26.6%
Q3 2021+29.8%+20.3%-26.6%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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