NASDAQ$TWST

Twist Bioscience Corporation · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

Twist Bioscience reported Q2 2025, revenue of $92.8M, net loss of $39.3M, diluted EPS of $-0.66.

For Q2 2025, Twist Bioscience reported revenue of $92.8M, a net loss of $39.3M, diluted EPS was $-0.66. Management discusses operating trends, capital, and sector risks in the quarterly filing.

  • Q2 2025 revenue $92.8M.
  • Net loss $39.3M.
  • Diluted EPS $-0.66.

Headline financials

Total Revenue

$92.8M

Previous: $75.3M+23.2%
EPS (adj)

-$0.66

Previous: -$0.79+16.5%
Gross Margin

49.6%

No prior period
Adjusted EBITDA

-$14.8M

No prior period
Capital Expenditures

-$6.41M

Previous: -$2.11M-204.0%
Net Income

-$39.3M

Previous: -$45.5M+13.5%
Operating Income

-$39.3M

Previous: -$48.9M+19.6%
Gross Profit

$46M

Previous: $30.9M+49.0%

Revenue & EPS history

Twist Bioscience · Revenue · Quarterly

$92.8M

Q2 2025+23.2%vs Q2 2024
Beat estimate in 15 of 15 quarters(100%)
ActualEstimate

Revenue by segment

Twist Bioscience · $218M total across 2 segments · Q3 2023

  • NGS Applications
    $120M+23.7%
  • DNA Synthesis & Protein
    $98M+22.5%

Forward guidance

Growth and biotech filers emphasize pipeline, commercial ramp, and cash runway rather than near-term GAAP profitability targets.

Tailwinds

  • Product revenue growth or launch momentum.
  • Partnership and platform expansion.
  • Balance sheet liquidity for R&D.

Headwinds

  • Operating losses until scale is reached.
  • R&D and SG&A spend ahead of revenue.
  • Regulatory and reimbursement risk.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2025

Historical avgQ2 2025

+0.1%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+0.8%

Avg return

30 days after

47%

14 / 30 earnings

Positive

+29.7%

Q4 2023

Best reaction

-23.2%

Q1 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026-7.3%-5.9%+19.6%
Q1 2026+13.8%-5.9%-10.2%
Q4 2025-10.0%-14.9%+3.4%
Q2 2025-8.5%-16.9%-20.8%
Q1 2025+0.7%-0.1%-19.7%
Q4 2024+12.0%+14.5%+20.9%
Q3 2024-14.6%-16.0%-18.5%
Q2 2024+28.9%+34.9%+31.1%
Q1 2024+9.5%+5.1%+16.9%
Q4 2023+29.7%+24.9%+81.5%
Q3 2023+14.9%+9.3%+14.0%
Q2 2023+3.6%+2.1%+26.0%
Q1 2023-23.2%-15.2%-37.1%
Q4 2022+0.8%+0.5%-0.6%
Q3 2022+20.8%+12.4%-17.2%
Q2 2022-9.9%-16.3%-12.6%
Q1 2022-1.0%+6.0%-21.0%
Q4 2021-12.6%-14.1%-22.4%
Q3 2021-9.1%-15.8%-7.6%
Q2 2021+6.2%-9.4%-12.4%
Q1 2021-16.8%-5.5%-38.1%
Q4 2020-9.9%-0.8%+44.3%
Q3 2020-7.2%-16.3%-4.8%
Q2 2020+5.1%+4.6%+0.7%
Q1 2020+21.3%+14.0%+31.4%
Q4 2019+4.6%+5.8%-15.5%
Q3 2019-11.2%-11.8%-13.9%
Q2 2019-9.9%-9.7%-3.9%
Q1 2019-9.2%-11.8%-6.9%
Q4 2018-9.2%-9.4%+18.6%
Q3 2018
Q2 2018
Q1 2017
Q4 2017

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