NASDAQ$TWST

Twist Bioscience Corporation · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Reported record revenue and improved gross margin.

Twist Bioscience reported a strong start to fiscal year 2025, achieving record revenue of $88.7 million, a 24% increase compared to the same period last year, and a gross margin of 48.3%, which is a 7.8 margin points improvement year-over-year.

  • Total revenue for the first quarter of fiscal 2025 grew to $88.7 million, a 24% increase compared to the same period in fiscal 2024.
  • Gross margin for the first quarter of fiscal 2025 increased to 48.3% compared to 40.5% for the same period in fiscal 2024.
  • Net loss attributable to common stockholders for the first quarter of fiscal 2025 was $31.6 million, or $0.53 per share, compared to $43.0 million, or $0.75 per share, for the same period of fiscal 2024.
  • As of December 31, 2024, the company had $270.8 million in cash, cash equivalents and short-term investments.

Headline financials

Total Revenue

$88.7M

Previous: $71.5M+24.1%
EPS (adj)

-$0.53

Previous: -$0.75+29.3%
Gross Margin

48.3%

No prior period
Adjusted EBITDA

-$16.3M

No prior period
Capital Expenditures

-$2.27M

Previous: -$1.51M-50.6%
Net Income

-$31.6M

Previous: -$43M+26.5%
Operating Income

-$34.6M

Previous: -$47M+26.3%
Gross Profit

$42.8M

Previous: $29M+47.9%
Stock-Based Comp

$12M

Previous: $11M+8.8%

Revenue & EPS history

Twist Bioscience · Revenue · Quarterly

$88.7M

Q1 2025+24.1%vs Q1 2024
Beat estimate in 15 of 15 quarters(100%)
ActualEstimate

Revenue by segment

Twist Bioscience · $218M total across 2 segments · Q3 2023

  • NGS Applications
    $120M+23.7%
  • DNA Synthesis & Protein
    $98M+22.5%

Forward guidance

Twist Bioscience expects revenue in the range of $372 million to $379 million for full year fiscal 2025 and expects gross margin over 50% for 4QFY25.

Tailwinds

  • Total revenue to be in the range of $372 million to $379 million compared to the previous guidance of $367 million to $377 million, indicating growth of 19 to 21 percent year over year
  • SynBio revenue of $144 million to $147 million, compared to previous guidance of $142 million to $146 million, growth of 17 to 18 percent
  • NGS revenue of $205 million to $209 million, compared to previous guidance of $204 million to $209 million, growth of 21 to 24 percent
  • Biopharma revenue of $23 million, compared to previous guidance of $21 million to $22 million, growth of 13 percent
  • Gross margin is projected to be approximately 49% for fiscal 2025 with quarterly sequential improvements, compared to previous guidance of 48% and 4QFY25 gross margin is projected to be over 50%

Headwinds

  • Adjusted EBITDA of approximately $(55) million to $(60) million for fiscal 2025 compared to previous guidance of $(60) million to $(65) million
  • Total revenue of approximately $91 million to $93 million for the second quarter
  • SynBio revenue of approximately $35.5 million to $36 million for the second quarter
  • NGS revenue of approximately $50 million to $51 million for the second quarter
  • Biopharma revenue of approximately $5.5 million to $6.0 million for the second quarter

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.1%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+0.8%

Avg return

30 days after

47%

14 / 30 earnings

Positive

+29.7%

Q4 2023

Best reaction

-23.2%

Q1 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026-7.3%-5.9%+19.6%
Q1 2026+13.8%-5.9%-10.2%
Q4 2025-10.0%-14.9%+3.4%
Q2 2025-8.5%-16.9%-20.8%
Q1 2025+0.7%-0.1%-19.7%
Q4 2024+12.0%+14.5%+20.9%
Q3 2024-14.6%-16.0%-18.5%
Q2 2024+28.9%+34.9%+31.1%
Q1 2024+9.5%+5.1%+16.9%
Q4 2023+29.7%+24.9%+81.5%
Q3 2023+14.9%+9.3%+14.0%
Q2 2023+3.6%+2.1%+26.0%
Q1 2023-23.2%-15.2%-37.1%
Q4 2022+0.8%+0.5%-0.6%
Q3 2022+20.8%+12.4%-17.2%
Q2 2022-9.9%-16.3%-12.6%
Q1 2022-1.0%+6.0%-21.0%
Q4 2021-12.6%-14.1%-22.4%
Q3 2021-9.1%-15.8%-7.6%
Q2 2021+6.2%-9.4%-12.4%
Q1 2021-16.8%-5.5%-38.1%
Q4 2020-9.9%-0.8%+44.3%
Q3 2020-7.2%-16.3%-4.8%
Q2 2020+5.1%+4.6%+0.7%
Q1 2020+21.3%+14.0%+31.4%
Q4 2019+4.6%+5.8%-15.5%
Q3 2019-11.2%-11.8%-13.9%
Q2 2019-9.9%-9.7%-3.9%
Q1 2019-9.2%-11.8%-6.9%
Q4 2018-9.2%-9.4%+18.6%
Q3 2018
Q2 2018
Q1 2017
Q4 2017

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