NASDAQ$SNDX

Syndax Pharmaceuticals Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

Syndax reported third quarter financial results and provided a business update.

Syndax Pharmaceuticals reported its Q3 2022 financial results, highlighting positive data from the AUGMENT-101 trial of revumenib and the completion of enrollment in the pivotal AGAVE-201 trial of axatilimab. The company is on track for two U.S. registrational filings by the end of 2023.

  • Updated data from the Phase 1 portion of the AUGMENT-101 trial demonstrated a CR/CRh rate of 30% and a median durability of response of 9.1 months.
  • Enrollment is complete in the pivotal Phase 2 AGAVE-201 trial of axatilimab in patients with cGVHD.
  • The company remains on track for two U.S. registrational filings by the end of 2023.
  • Updated positive data from the Phase 1 portion of the ongoing AUGMENT-101 trial of revumenib will be featured during two oral presentations at the American Society of Hematology (ASH) Annual Meeting in December.

Headline financials

Total Revenue

$12.4M

Previous: $12.4M+0.0%
EPS (adj)

-$0.58

Previous: -$0.40-45.0%
R&D Expenses

$26.9M

Previous: $25.6M+5.1%
SG&A Expenses

$8.24M

Previous: $6.8M+21.2%
Total Operating Expenses

$35.1M

No prior period
Free Cash Flow

-$35.4M

Previous: -$20.6M-71.5%
Net Income

-$35.4M

Previous: -$20.6M-71.5%
Operating Income

-$35.1M

Previous: -$20M-75.4%
Gross Profit

$0.00

Previous: $0.00
Cash & Equivalents

$71.4M

Previous: $71.4M-0.1%
Total Assets

$360M

Previous: $240M+50.2%
Stock-Based Comp

$4.36M

Previous: $3.38M+29.0%

Revenue & EPS history

Syndax · Revenue · Quarterly

$12.4M

Q3 2022+0%vs Q3 2021
Beat estimate in 2 of 8 quarters(25%)
ActualEstimate

Forward guidance

For the full year of 2022, the Company is lowering its expectations of both research and development and total operating expenses. The updated guidance reflects the benefits derived from the shared expenses for our axatilimab cGVHD development program.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

+1.6%

Avg return

Earnings day

+0.9%

Avg return

5 days after

+3.5%

Avg return

30 days after

60%

24 / 40 earnings

Positive

+15.1%

Q4 2019

Best reaction

-21.6%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.9%-2.6%-5.2%
Q4 2025+5.1%+4.6%+13.6%
Q3 2025+11.6%+9.3%+43.5%
Q1 2025-21.6%-21.1%-17.8%
Q4 2024-7.1%-13.3%-19.5%
Q3 2024+12.7%+15.2%-11.3%
Q2 2024-7.3%-12.3%-9.5%
Q1 2024-5.2%-9.5%-15.9%
Q4 2023-2.1%-2.7%-2.4%
Q3 2023+6.3%+5.0%+19.0%
Q2 2023-3.5%-10.9%-4.5%
Q1 2023+7.8%+5.0%+3.8%
Q4 2022+1.6%-0.1%-15.6%
Q3 2022-2.0%-2.2%+9.5%
Q2 2022+0.5%+0.5%-2.4%
Q1 2022-5.8%-12.3%+10.1%
Q4 2021+3.3%-2.2%+11.5%
Q3 2021+2.1%-0.9%+5.9%
Q2 2021+7.0%+11.2%+23.9%
Q1 2021+14.6%+18.5%+21.5%
Q4 2020+0.4%-2.8%-5.3%
Q3 2020+8.8%+20.4%+30.9%
Q2 2020+6.5%-0.9%+0.7%
Q1 2020-1.8%+3.2%-8.0%
Q4 2019+15.1%+22.8%-0.6%
Q3 2019-0.3%+0.3%+24.5%
Q2 2019+10.6%+8.6%-3.0%
Q1 2019+9.1%+6.1%+3.9%
Q4 2018-13.5%-11.1%-4.2%
Q3 2018+2.1%+5.9%-3.5%
Q2 2018+12.0%+6.7%+8.8%
Q1 2018+9.9%+1.5%-25.5%
Q4 2017-1.5%-0.6%+47.9%
Q3 2017-11.7%-10.1%-28.4%
Q2 2017-5.7%-1.5%+8.0%
Q1 2017-7.0%+4.7%+26.7%
Q4 2016+5.0%+1.0%+18.0%
Q3 2016+0.9%-4.9%-17.1%
Q2 2016+5.6%+5.5%+3.1%
Q1 2016-2.1%
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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