NASDAQ$SNDX
Syndax Pharmaceuticals Inc · Q1 2024 earnings
Q1 2024 earnings · · Investor relations
Briefing
Syndax reported first quarter 2024 financial results and provided a business update.
Syndax Pharmaceuticals reported its financial results for the quarter ended March 31, 2024. The company highlighted the potential near-term approvals of revumenib and axatilimab, as well as pivotal data expected from the AUGMENT-101 trial in the fourth quarter. The company had cash, cash equivalents, and short and long-term investments of $522.0 million as of March 31, 2024.
- NDA filing for revumenib in R/R KMT2Ar acute leukemia granted Priority Review under RTOR with a PDUFA action date set for September 26, 2024.
- BLA filing for axatilimab in chronic GVHD granted Priority Review with a PDUFA action date set for August 28, 2024.
- Enrollment completed in AUGMENT-101 mNPM1 cohort; topline data expected in 4Q24 to potentially support sNDA filing in 1H25.
- Company to host conference call today at 8:00 a.m. ET.
Headline financials
Revenue & EPS history
Syndax · Revenue · Quarterly
$0
Forward guidance
For the second quarter of 2024, the Company expects research and development expenses to be $50 to $55 million and total operating expenses to be $80 to $85 million. For the full year of 2024, the Company continues to expect research and development expenses to be $240 to $260 million and total operating expenses to be $355 to $375 million, which includes an estimated $43 million in non-cash stock compensation expense. The Company believes that it has sufficient cash runway to fund its research, clinical development and commercial operations through 2026.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2024
+1.6%
Avg return
Earnings day
+0.9%
Avg return
5 days after
+3.5%
Avg return
30 days after
60%
24 / 40 earnings
Positive
+15.1%
Q4 2019
Best reaction
-21.6%
Q1 2025
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +3.9% | -2.6% | -5.2% | |
| Q4 2025 | +5.1% | +4.6% | +13.6% | |
| Q3 2025 | +11.6% | +9.3% | +43.5% | |
| Q1 2025 | -21.6% | -21.1% | -17.8% | |
| Q4 2024 | -7.1% | -13.3% | -19.5% | |
| Q3 2024 | +12.7% | +15.2% | -11.3% | |
| Q2 2024 | -7.3% | -12.3% | -9.5% | |
| Q1 2024 | -5.2% | -9.5% | -15.9% | |
| Q4 2023 | -2.1% | -2.7% | -2.4% | |
| Q3 2023 | +6.3% | +5.0% | +19.0% | |
| Q2 2023 | -3.5% | -10.9% | -4.5% | |
| Q1 2023 | +7.8% | +5.0% | +3.8% | |
| Q4 2022 | +1.6% | -0.1% | -15.6% | |
| Q3 2022 | -2.0% | -2.2% | +9.5% | |
| Q2 2022 | +0.5% | +0.5% | -2.4% | |
| Q1 2022 | -5.8% | -12.3% | +10.1% | |
| Q4 2021 | +3.3% | -2.2% | +11.5% | |
| Q3 2021 | +2.1% | -0.9% | +5.9% | |
| Q2 2021 | +7.0% | +11.2% | +23.9% | |
| Q1 2021 | +14.6% | +18.5% | +21.5% | |
| Q4 2020 | +0.4% | -2.8% | -5.3% | |
| Q3 2020 | +8.8% | +20.4% | +30.9% | |
| Q2 2020 | +6.5% | -0.9% | +0.7% | |
| Q1 2020 | -1.8% | +3.2% | -8.0% | |
| Q4 2019 | +15.1% | +22.8% | -0.6% | |
| Q3 2019 | -0.3% | +0.3% | +24.5% | |
| Q2 2019 | +10.6% | +8.6% | -3.0% | |
| Q1 2019 | +9.1% | +6.1% | +3.9% | |
| Q4 2018 | -13.5% | -11.1% | -4.2% | |
| Q3 2018 | +2.1% | +5.9% | -3.5% | |
| Q2 2018 | +12.0% | +6.7% | +8.8% | |
| Q1 2018 | +9.9% | +1.5% | -25.5% | |
| Q4 2017 | -1.5% | -0.6% | +47.9% | |
| Q3 2017 | -11.7% | -10.1% | -28.4% | |
| Q2 2017 | -5.7% | -1.5% | +8.0% | |
| Q1 2017 | -7.0% | +4.7% | +26.7% | |
| Q4 2016 | +5.0% | +1.0% | +18.0% | |
| Q3 2016 | +0.9% | -4.9% | -17.1% | |
| Q2 2016 | +5.6% | +5.5% | +3.1% | |
| Q1 2016 | -2.1% | — | — | |
| Q4 2015 | — | — | — | |
| Q3 2015 | — | — | — | |
| Q2 2015 | — | — | — | |
| Q1 2015 | — | — | — | |
| Q4 2014 | — | — | — | |
| Q3 2014 | — | — | — | |
| Q2 2014 | — | — | — | |
| Q1 2014 | — | — | — | |
| Q4 2013 | — | — | — | |
| Q3 2013 | — | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — |
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